Michel Goedert
Michel Goedert
MRC Laboratory of Molecular Biology, Cambridge, UK
Verifisert e-postadresse på mrc-lmb.cam.ac.uk - Startside
Sitert av
Sitert av
α-Synuclein in Lewy bodies
MG Spillantini, ML Schmidt, VMY Lee, JQ Trojanowski, R Jakes, ...
Nature 388 (6645), 839-840, 1997
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies
MG Spillantini, RA Crowther, R Jakes, M Hasegawa, M Goedert
Proceedings of the National Academy of Sciences 95 (11), 6469-6473, 1998
Neurodegenerative tauopathies
VMY Lee, M Goedert, JQ Trojanowski
Annual review of neuroscience 24 (1), 1121-1159, 2001
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
M Goedert, MG Spillantini, R Jakes, D Rutherford, RA Crowther
Neuron 3 (4), 519-526, 1989
A century of Alzheimer's disease
M Goedert, MG Spillantini
science 314 (5800), 777-781, 2006
Transmission and spreading of tauopathy in transgenic mouse brain
F Clavaguera, T Bolmont, RA Crowther, D Abramowski, S Frank, A Probst, ...
Nature cell biology 11 (7), 909-913, 2009
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
MG Spillantini, JR Murrell, M Goedert, MR Farlow, A Klug, B Ghetti
Proceedings of the National Academy of Sciences 95 (13), 7737-7741, 1998
Alpha-synuclein and neurodegenerative diseases
M Goedert
Nature reviews neuroscience 2 (7), 492-501, 2001
Cryo-EM structures of tau filaments from Alzheimer’s disease
AWP Fitzpatrick, B Falcon, S He, AG Murzin, G Murshudov, HJ Garringer, ...
Nature 547 (7662), 185-190, 2017
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
M Goedert, CM Wischik, RA Crowther, JE Walker, A Klug
Proceedings of the National Academy of Sciences 85 (11), 4051-4055, 1988
Identification of two distinct synucleins from human brain
R Jakes, MG Spillantini, M Goedert
FEBS letters 345 (1), 27-32, 1994
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
M Goedert, MG Spillantini, NJ Cairns, RA Crowther
Neuron 8 (1), 159-168, 1992
Cloning and sequencing of the cDNA encoding an isoform of microtubule‐associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in …
M Goedert, MG Spillantini, MC Potier, J Ulrich, RA Crowther
The EMBO journal 8 (2), 393-399, 1989
100 years of Lewy pathology
M Goedert, MG Spillantini, K Del Tredici, H Braak
Nature Reviews Neurology 9 (1), 13-24, 2013
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
M Goedert, R Jakes, MG Spillantini, M Hasegawa, MJ Smith, RA Crowther
Nature 383 (6600), 550-553, 1996
Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
MG Spillantini, RA Crowther, R Jakes, NJ Cairns, PL Lantos, M Goedert
Neuroscience letters 251 (3), 205-208, 1998
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
GT Bramblett, M Goedert, R Jakes, SE Merrick, JQ Trojanowski, VMY Lee
Neuron 10 (6), 1089-1099, 1993
Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.
M Goedert, R Jakes
The EMBO journal 9 (13), 4225-4230, 1990
Tau pathology and neurodegeneration
MG Spillantini, M Goedert
The Lancet Neurology 12 (6), 609-622, 2013
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
LC Serpell, J Berriman, R Jakes, M Goedert, RA Crowther
Proceedings of the National Academy of Sciences 97 (9), 4897-4902, 2000
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