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| Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells H Niwa, J Miyazaki, AG Smith Nature genetics 24 (4), 372-376, 2000 | 4617 | 2000 |
| Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ... Cell 95 (3), 379-391, 1998 | 4361 | 1998 |
| Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 H Niwa, T Burdon, I Chambers, A Smith Genes & development 12 (13), 2048-2060, 1998 | 2006 | 1998 |
| Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells S Masui, Y Nakatake, Y Toyooka, D Shimosato, R Yagi, K Takahashi, ... Nature cell biology 9 (6), 625-635, 2007 | 1646 | 2007 |
| Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation H Niwa, Y Toyooka, D Shimosato, D Strumpf, K Takahashi, R Yagi, ... Cell 123 (5), 917-929, 2005 | 1426 | 2005 |
| The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass N Nishioka, K Inoue, K Adachi, H Kiyonari, M Ota, A Ralston, N Yabuta, ... Developmental cell 16 (3), 398-410, 2009 | 1079 | 2009 |
| How is pluripotency determined and maintained? H Niwa Oxford University Press for The Company of Biologists Limited 134 (4), 635-646, 2007 | 1048 | 2007 |
| A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells H Niwa, K Ogawa, D Shimosato, K Adachi Nature 460 (7251), 118-122, 2009 | 1021 | 2009 |
| Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2 MH Vitaterna, CP Selby, T Todo, H Niwa, C Thompson, EM Fruechte, ... Proceedings of the National Academy of Sciences 96 (21), 12114-12119, 1999 | 876 | 1999 |
| Genome analysis of the platypus reveals unique signatures of evolution Nature 453 (7192), 175-183, 2008 | 772 | 2008 |
| Identification and characterization of subpopulations in undifferentiated ES cell culture Y Toyooka, D Shimosato, K Murakami, K Takahashi, H Niwa Oxford University Press for The Company of Biologists Limited 135 (5), 909-918, 2008 | 637 | 2008 |
| Differentiation of embryonic stem cells is induced by GATA factors J Fujikura, E Yamato, S Yonemura, K Hosoda, S Masui, K Nakao, ... Genes & development 16 (7), 784-789, 2002 | 624 | 2002 |
| Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice K Miyawaki, Y Yamada, H Yano, H Niwa, N Ban, Y Ihara, A Kubota, ... Proceedings of the National Academy of Sciences 96 (26), 14843-14847, 1999 | 585 | 1999 |
| Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells S Okumura-Nakanishi, M Saito, H Niwa, F Ishikawa Journal of Biological Chemistry 280 (7), 5307-5317, 2005 | 527 | 2005 |
| Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells M Ohgushi, M Matsumura, M Eiraku, K Murakami, T Aramaki, A Nishiyama, ... Cell stem cell 7 (2), 225-239, 2010 | 493 | 2010 |
| Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis S Takashima, M Kitakaze, M Asakura, H Asanuma, S Sanada, F Tashiro, ... Proceedings of the National Academy of Sciences 99 (6), 3657-3662, 2002 | 491 | 2002 |
| Molecular mechanism to maintain stem cell renewal of ES cells H Niwa Cell structure and function 26 (3), 137-148, 2001 | 487 | 2001 |
| Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal G Martello, T Sugimoto, E Diamanti, A Joshi, R Hannah, S Ohtsuka, ... Cell stem cell 11 (4), 491-504, 2012 | 441 | 2012 |
| Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP) H Hashimoto, N Shintani, K Tanaka, W Mori, M Hirose, T Matsuda, ... Proceedings of the National Academy of Sciences 98 (23), 13355-13360, 2001 | 412 | 2001 |
