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Jean-Philippe Brosseau
Jean-Philippe Brosseau
Verifisert e-postadresse på utsouthwestern.edu - Startside
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Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours
H Yao, J Lan, C Li, H Shi, JP Brosseau, H Wang, H Lu, C Fang, Y Zhang, ...
Nature biomedical engineering 3 (4), 306-317, 2019
3122019
Identification of alternative splicing markers for breast cancer
JP Venables, R Klinck, A Bramard, L Inkel, G Dufresne-Martin, CS Koh, ...
Cancer research 68 (22), 9525-9531, 2008
2442008
RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues
JP Venables, JP Brosseau, G Gadea, R Klinck, P Prinos, JF Beaulieu, ...
Molecular and cellular biology 33 (2), 396-405, 2013
1642013
Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis
CP Liao, RC Booker, JP Brosseau, Z Chen, J Mo, E Tchegnon, Y Wang, ...
The Journal of clinical investigation 128 (7), 2848-2861, 2018
1272018
Alternative splicing of SYK regulates mitosis and cell survival
P Prinos, D Garneau, JF Lucier, D Gendron, S Couture, M Boivin, ...
Nature structural & molecular biology 18 (6), 673-679, 2011
1192011
High-throughput quantification of splicing isoforms
JP Brosseau, JF Lucier, E Lapointe, M Durand, D Gendron, J Gervais-Bird, ...
Rna 16 (2), 442-449, 2010
962010
Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway
Z Chen, J Mo, JP Brosseau, T Shipman, Y Wang, CP Liao, JM Cooper, ...
Cancer discovery 9 (1), 114-129, 2019
682019
Tumor microenvironment–associated modifications of alternative splicing
JP Brosseau, JF Lucier, H Nwilati, P Thibault, D Garneau, D Gendron, ...
Rna 20 (2), 189-201, 2014
642014
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation
JP Brosseau, CP Liao, Y Wang, V Ramani, T Vandergriff, M Lee, A Patel, ...
Nature communications 9 (1), 5014, 2018
522018
Trametinib induces neurofibroma shrinkage and enables surgery
P Vaassen, N Dürr, A Röhrig, R Willing, T Rosenbaum
Neuropediatrics 50 (05), 300-303, 2019
482019
Redirecting splicing with bifunctional oligonucleotides
JP Brosseau, JF Lucier, AA Lamarche, L Shkreta, D Gendron, E Lapointe, ...
Nucleic acids research 42 (6), e40-e40, 2014
412014
The biology of cutaneous neurofibromas: consensus recommendations for setting research priorities
JP Brosseau, DC Pichard, EH Legius, P Wolkenstein, RM Lavker, ...
Neurology 91 (2_Supplement_1), S14-S20, 2018
382018
8‐BuS‐ATP derivatives as specific NTPD ase1 inhibitors
J Lecka, I Gillerman, M Fausther, M Salem, MN Munkonda, JP Brosseau, ...
British Journal of Pharmacology 169 (1), 179-196, 2013
332013
A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions
H Yao, C Li, F He, T Song, JP Brosseau, H Wang, H Lu, C Fang, H Shi, ...
RSC Chemical Biology 2 (1), 192-205, 2021
322021
Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing
JP Brosseau, AA Sathe, Y Wang, T Nguyen, DA Glass, C Xing, LQ Le
Acta Neuropathologica Communications 9, 1-11, 2021
302021
Translating current basic research into future therapies for neurofibromatosis type 1
JP Brosseau, CP Liao, LQ Le
British journal of cancer 123 (2), 178-186, 2020
262020
Targeted degradation of immune checkpoint proteins: emerging strategies for cancer immunotherapy
J Xu, JP Brosseau, H Shi
Oncogene 39 (48), 7106-7113, 2020
232020
Spatiotemporal loss of NF1 in schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the hippo pathway. Cancer Discov. 2019; 9 …
Z Chen, J Mo, JP Brosseau, T Shipman, Y Wang, CP Liao, JM Cooper, ...
CD-18-0151.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
17
Toward understanding the mechanisms of malignant peripheral nerve sheath tumor development
T Mohamad, C Plante, JP Brosseau
International Journal of Molecular Sciences 22 (16), 8620, 2021
142021
Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
Z Chen, S Li, J Mo, E Hawley, Y Wang, Y He, JP Brosseau, T Shipman, ...
JCI insight 5 (20), 2020
142020
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Artikler 1–20