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Jacques Huot
Jacques Huot
Professeur Émérite- Faculté de médecine de l'Université Laval
Verifisert e-postadresse på fmed.ulaval.ca
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Endothelial cell migration during angiogenesis
L Lamalice, F Le Boeuf, J Huot
Circulation research 100 (6), 782-794, 2007
17372007
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
S Rousseau, F Houle, J Landry, J Huot
Oncogene 15 (18), 2169-2177, 1997
10821997
Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27
J Guay, H Lambert, G Gingras-Breton, JN Lavoie, J Huot, J Landry
Journal of cell science 110 (3), 357-368, 1997
8751997
Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
J Huot, F Houle, F Marceau, J Landry
Circulation research 80 (3), 383-392, 1997
6921997
HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
J Huot, F Houle, DR Spitz, J Landry
Cancer research 56 (2), 273-279, 1996
6231996
Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta
S Giroux, M Tremblay, D Bernard, JF Cardin-Girard, S Aubry, L Larouche, ...
Current Biology 9 (7), 369-376, 1999
4661999
Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38 …
S Rousseau, F Houle, H Kotanides, L Witte, J Waltenberger, J Landry, ...
Journal of Biological Chemistry 275 (14), 10661-10672, 2000
4042000
SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
J Huot, F Houle, S Rousseau, RG Deschesnes, GM Shah, J Landry
The Journal of cell biology 143 (5), 1361-1373, 1998
3801998
IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation
L Roussel, F Houle, C Chan, Y Yao, J Bérubé, R Olivenstein, JG Martin, ...
The Journal of Immunology 184 (8), 4531-4537, 2010
3372010
Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27
J Landry, J Huot
Biochemistry and cell biology 73 (9-10), 703-707, 1995
3161995
Increased Survival after Treatments with Anticancer Agents of Chinese Hamster Cells Expressing the Human Mr 27,000 Heat Shock Protein
J Huot, G Roy, H Lambert, P Chrétien, J Landry
Cancer research 51 (19), 5245-5252, 1991
3051991
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
L Lamalice, F Houle, G Jourdan, J Huot
Oncogene 23 (2), 434-445, 2004
3002004
Role of cancer microenvironment in metastasis: focus on colon cancer
S Gout, J Huot
Cancer Microenvironment 1, 69-83, 2008
2492008
Characterization of 45‐kDa/54‐kDa HSP27 kinase, a stress‐sensitive kinase which may activate the phosphorylation‐dependent protective function of mammalian 27‐kDa heat‐shock …
J Huot, H Lambert, JN Lavoie, A Guimond, F Houle, J Landry
European journal of biochemistry 227 (1‐2), 416-427, 1995
2371995
Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF
L Lamalice, F Houle, J Huot
Journal of Biological Chemistry 281 (45), 34009-34020, 2006
2112006
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
L Zhong, MJ Simard, J Huot
The FASEB Journal 32 (8), 4070-4084, 2018
1902018
Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis
S Gout, PL Tremblay, J Huot
Clinical & experimental metastasis 25, 335-344, 2008
1852008
Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases
PL Tremblay, FA Auger, J Huot
Oncogene 25 (50), 6563-6573, 2006
1852006
Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities
F Le Boeuf, F Houle, J Huot
Journal of Biological Chemistry 279 (37), 39175-39185, 2004
1782004
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells
I Corre, F Paris, J Huot
Oncotarget 8 (33), 55684, 2017
1762017
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Artikler 1–20