SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology FP Veras, MC Pontelli, CM Silva, JE Toller-Kawahisa, M de Lima, ... Journal of Experimental Medicine 217 (12), e20201129, 2020 | 844 | 2020 |
Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients TS Rodrigues, KSG de Sá, AY Ishimoto, A Becerra, S Oliveira, L Almeida, ... Journal of Experimental Medicine 218 (3), 2021 | 734 | 2021 |
PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation LEA Damasceno, DS Prado, FP Veras, MM Fonseca, JE Toller-Kawahisa, ... Journal of Experimental Medicine 217 (10), e20190613, 2020 | 150 | 2020 |
Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation CMS Silva, CWS Wanderley, FP Veras, F Sonego, DC Nascimento, ... Blood, The Journal of the American Society of Hematology 138 (25), 2702-2713, 2021 | 124 | 2021 |
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation S McArthur, G Juban, T Gobbetti, T Desgeorges, M Theret, J Gondin, ... The Journal of clinical investigation 130 (3), 1156-1167, 2020 | 120 | 2020 |
Neutrophil extracellular traps effectively control acute chikungunya virus infection CH Hiroki, JE Toller-Kawahisa, MJ Fumagalli, DF Colon, LTM Figueiredo, ... Frontiers in immunology 10, 3108, 2020 | 102 | 2020 |
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, ... Nature 615 (7952), 490-498, 2023 | 55 | 2023 |
Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity DC Nascimento, PR Viacava, RG Ferreira, MA Damaceno, AR Piñeros, ... Immunity 54 (9), 2024-2041. e8, 2021 | 54 | 2021 |
Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology CMS Silva, CWS Wanderley, FP Veras, AV Gonçalves, MHF Lima, ... Critical Care 26 (1), 206, 2022 | 41 | 2022 |
SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients MC Pontelli, ÍA Castro, RB Martins, L La Serra, FP Veras, DC Nascimento, ... Journal of Molecular Cell Biology 14 (4), mjac021, 2022 | 38 | 2022 |
Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells ACG Salina, D Dos-Santos, TS Rodrigues, M Fortes-Rocha, ... Elife 11, e74443, 2022 | 34 | 2022 |
Inflammasome activation in COVID-19 patients TS Rodrigues, KSG de Sá, AY Ishimoto, A Becerra, S Oliveira, L Almeida, ... MedRxiv, 2020.08. 05.20168872, 2020 | 34 | 2020 |
MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression JPM Luiz, JE Toller-Kawahisa, PR Viacava, DC Nascimento, PT Pereira, ... Journal of Leucocyte Biology 108 (4), 1215-1223, 2020 | 30 | 2020 |
FcγRIIa and FcγRIIIb polymorphisms and associations with clinical manifestations in systemic lupus erythematosus patients ICC Vigato-Ferreira, JE Toller-Kawahisa, JAT Pancoto, CT Mendes-Junior, ... Autoimmunity 47 (7), 451-458, 2014 | 25 | 2014 |
The variant of CD11b, rs1143679 within ITGAM, is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients JE Toller-Kawahisa, ICC Vigato-Ferreira, JAT Pancoto, CT Mendes-Junior, ... Human immunology 75 (2), 119-123, 2014 | 23 | 2014 |
Systemic lupus erythematosus onset in lupus-prone B6. MRL/lpr mice is influenced by weight gain and is preceded by an increase in neutrophil oxidative burst activity JE Toller-Kawahisa, NC Canicoba, VP Venancio, R Kawahisa, ... Free Radical Biology and Medicine 86, 362-373, 2015 | 17 | 2015 |
Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory programming and continual clearance of apoptotic cells (preprint) D dos-Santos, ACG Salina, TS Rodrigues, MF Rocha, EG Freitas-Filho, ... | 15 | 2021 |
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, ECO Brien, ... Nature Communications 14 (1), 3513, 2023 | 14 | 2023 |
How neutrophil metabolism affects bacterial killing JE Toller-Kawahisa, LAJ O'Neill Open Biology 12 (11), 220248, 2022 | 13 | 2022 |
Influence of FcγRIIIb polymorphism on its ability to cooperate with FcγRIIa and CR3 in mediating the oxidative burst of human neutrophils AC Urbaczek, JE Toller-Kawahisa, LM Fonseca, PI Costa, CMQG Faria, ... Human Immunology 75 (8), 785-790, 2014 | 13 | 2014 |