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Chul-Hwan Lee
Chul-Hwan Lee
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Capturing the onset of PRC2-mediated repressive domain formation
O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ...
Molecular cell 70 (6), 1149-1162. e5, 2018
2372018
PRC2 is high maintenance
JR Yu, CH Lee, O Oksuz, JM Stafford, D Reinberg
Genes & development 33 (15-16), 903-935, 2019
2222019
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma
JM Stafford, CH Lee, P Voigt, N Descostes, R Saldaña-Meyer, JR Yu, ...
Science advances 4 (10), eaau5935, 2018
1472018
Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin
CH Lee, JR Yu, S Kumar, Y Jin, G LeRoy, N Bhanu, S Kaneko, BA Garcia, ...
Molecular cell 70 (3), 422-434. e6, 2018
1222018
H1 histones control the epigenetic landscape by local chromatin compaction
MA Willcockson, SE Healton, CN Weiss, BA Bartholdy, Y Botbol, ...
Nature 589 (7841), 293-298, 2021
1202021
Distinct stimulatory mechanisms regulate the catalytic activity of polycomb repressive complex 2
CH Lee, M Holder, D Grau, R Saldaña-Meyer, JR Yu, RA Ganai, J Zhang, ...
Molecular cell 70 (3), 435-448. e5, 2018
1162018
Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes
YH Kang, CH Lee, YS Seo
Critical reviews in biochemistry and molecular biology 45 (2), 71-96, 2010
912010
Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma
CH Lee, JR Yu, J Granat, R Saldaña-Meyer, J Andrade, G LeRoy, Y Jin, ...
Genes & development 33 (19-20), 1428-1440, 2019
882019
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells
G LeRoy, O Oksuz, N Descostes, Y Aoi, RA Ganai, HO Kara, JR Yu, ...
Science Advances 5 (10), eaay3068, 2019
642019
Chromatin remodelers fine-tune H3K36me-directed deacetylation of neighbor nucleosomes by Rpd3S
CH Lee, J Wu, B Li
Molecular cell 52 (2), 255-263, 2013
632013
Multivalent di‐nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels
JW Huh, J Wu, CH Lee, M Yun, D Gilada, CA Brautigam, B Li
The EMBO journal 31 (17), 3564-3574, 2012
562012
Structures of monomeric and dimeric PRC2: EZH1 reveal flexible modules involved in chromatin compaction
D Grau, Y Zhang, CH Lee, M Valencia-Sánchez, J Zhang, M Wang, ...
Nature communications 12 (1), 714, 2021
522021
Nucleosome contact triggers conformational changes of Rpd3S driving high-affinity H3K36me nucleosome engagement
C Ruan, CH Lee, H Cui, S Li, B Li
Cell reports 10 (2), 204-215, 2015
482015
Genetic and functional interactions between Mus81–Mms4 and Rad27
MJ Kang, CH Lee, YH Kang, IT Cho, TA Nguyen, YS Seo
Nucleic acids research 38 (21), 7611-7625, 2010
292010
The MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing
YH Kang, MJ Kang, JH Kim, CH Lee, I Cho, J Hurwitz, YS Seo
Journal of biological chemistry 284 (16), 10376-10386, 2009
282009
Homodimeric PHD domain-containing Rco1 subunit constitutes a critical interaction hub within the Rpd3S histone deacetylase complex
C Ruan, H Cui, CH Lee, S Li, B Li
Journal of Biological Chemistry 291 (10), 5428-5438, 2016
232016
Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing
M Lee, CH Lee, AA Demin, PR Munashingha, T Amangyeld, B Kwon, ...
Journal of Biological Chemistry 289 (21), 15064-15079, 2014
212014
Human replication factor C stimulates flap endonuclease 1
I Cho, D Kim, YH Kang, CH Lee, T Amangyelid, TA Nguyen, J Hurwitz, ...
Journal of biological chemistry 284 (16), 10387-10399, 2009
202009
The role of EZH1 and EZH2 in development and cancer
SH Lee, Y Li, H Kim, S Eum, K Park, CH Lee
BMB reports 55 (12), 595, 2022
182022
Analysis of subunit assembly and function of the Saccharomyces cerevisiae RNase H2 complex
TA Nguyen, YS Tak, CH Lee, YH Kang, IT Cho, YS Seo
The FEBS Journal 278 (24), 4927-4942, 2011
182011
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Artikler 1–20