Capturing the onset of PRC2-mediated repressive domain formation O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ... Molecular cell 70 (6), 1149-1162. e5, 2018 | 237 | 2018 |
PRC2 is high maintenance JR Yu, CH Lee, O Oksuz, JM Stafford, D Reinberg Genes & development 33 (15-16), 903-935, 2019 | 222 | 2019 |
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma JM Stafford, CH Lee, P Voigt, N Descostes, R Saldaña-Meyer, JR Yu, ... Science advances 4 (10), eaau5935, 2018 | 147 | 2018 |
Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin CH Lee, JR Yu, S Kumar, Y Jin, G LeRoy, N Bhanu, S Kaneko, BA Garcia, ... Molecular cell 70 (3), 422-434. e6, 2018 | 122 | 2018 |
H1 histones control the epigenetic landscape by local chromatin compaction MA Willcockson, SE Healton, CN Weiss, BA Bartholdy, Y Botbol, ... Nature 589 (7841), 293-298, 2021 | 120 | 2021 |
Distinct stimulatory mechanisms regulate the catalytic activity of polycomb repressive complex 2 CH Lee, M Holder, D Grau, R Saldaña-Meyer, JR Yu, RA Ganai, J Zhang, ... Molecular cell 70 (3), 435-448. e5, 2018 | 116 | 2018 |
Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes YH Kang, CH Lee, YS Seo Critical reviews in biochemistry and molecular biology 45 (2), 71-96, 2010 | 91 | 2010 |
Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma CH Lee, JR Yu, J Granat, R Saldaña-Meyer, J Andrade, G LeRoy, Y Jin, ... Genes & development 33 (19-20), 1428-1440, 2019 | 88 | 2019 |
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells G LeRoy, O Oksuz, N Descostes, Y Aoi, RA Ganai, HO Kara, JR Yu, ... Science Advances 5 (10), eaay3068, 2019 | 64 | 2019 |
Chromatin remodelers fine-tune H3K36me-directed deacetylation of neighbor nucleosomes by Rpd3S CH Lee, J Wu, B Li Molecular cell 52 (2), 255-263, 2013 | 63 | 2013 |
Multivalent di‐nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels JW Huh, J Wu, CH Lee, M Yun, D Gilada, CA Brautigam, B Li The EMBO journal 31 (17), 3564-3574, 2012 | 56 | 2012 |
Structures of monomeric and dimeric PRC2: EZH1 reveal flexible modules involved in chromatin compaction D Grau, Y Zhang, CH Lee, M Valencia-Sánchez, J Zhang, M Wang, ... Nature communications 12 (1), 714, 2021 | 52 | 2021 |
Nucleosome contact triggers conformational changes of Rpd3S driving high-affinity H3K36me nucleosome engagement C Ruan, CH Lee, H Cui, S Li, B Li Cell reports 10 (2), 204-215, 2015 | 48 | 2015 |
Genetic and functional interactions between Mus81–Mms4 and Rad27 MJ Kang, CH Lee, YH Kang, IT Cho, TA Nguyen, YS Seo Nucleic acids research 38 (21), 7611-7625, 2010 | 29 | 2010 |
The MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing YH Kang, MJ Kang, JH Kim, CH Lee, I Cho, J Hurwitz, YS Seo Journal of biological chemistry 284 (16), 10376-10386, 2009 | 28 | 2009 |
Homodimeric PHD domain-containing Rco1 subunit constitutes a critical interaction hub within the Rpd3S histone deacetylase complex C Ruan, H Cui, CH Lee, S Li, B Li Journal of Biological Chemistry 291 (10), 5428-5438, 2016 | 23 | 2016 |
Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing M Lee, CH Lee, AA Demin, PR Munashingha, T Amangyeld, B Kwon, ... Journal of Biological Chemistry 289 (21), 15064-15079, 2014 | 21 | 2014 |
Human replication factor C stimulates flap endonuclease 1 I Cho, D Kim, YH Kang, CH Lee, T Amangyelid, TA Nguyen, J Hurwitz, ... Journal of biological chemistry 284 (16), 10387-10399, 2009 | 20 | 2009 |
The role of EZH1 and EZH2 in development and cancer SH Lee, Y Li, H Kim, S Eum, K Park, CH Lee BMB reports 55 (12), 595, 2022 | 18 | 2022 |
Analysis of subunit assembly and function of the Saccharomyces cerevisiae RNase H2 complex TA Nguyen, YS Tak, CH Lee, YH Kang, IT Cho, YS Seo The FEBS Journal 278 (24), 4927-4942, 2011 | 18 | 2011 |