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Qi Guo
Qi Guo
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Monoamine oxidase B inhibitor, selegiline, reduces 18 F-THK5351 uptake in the human brain
KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ...
Alzheimer's research & therapy 9 (1), 25, 2017
3302017
Neuroinflammation in treated HIV-positive individuals A TSPO PET study
JH Vera, Q Guo, JH Cole, A Boasso, L Greathead, P Kelleher, EA Rabiner, ...
Neurology 86 (15), 1425-1432, 2016
1642016
Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study
DR Owen, Q Guo, NJ Kalk, A Colasanti, D Kalogiannopoulou, R Dimber, ...
Journal of Cerebral Blood Flow & Metabolism 34 (6), 989-994, 2014
1412014
Hippocampal neuroinflammation, functional connectivity, and depressive symptoms in multiple sclerosis
A Colasanti, Q Guo, P Giannetti, MB Wall, RD Newbould, C Bishop, ...
Biological psychiatry 80 (1), 62-72, 2016
1362016
Archival Report
A Colasanti, Q Guo, P Giannetti, MB Wall, RD Newbould, C Bishop, ...
136*2016
In vivo assessment of brain white matter inflammation in multiple sclerosis with 18F-PBR111 PET
A Colasanti, Q Guo, N Muhlert, P Giannetti, M Onega, RD Newbould, ...
Journal of Nuclear Medicine 55 (7), 1112-1118, 2014
1052014
Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding
Q Guo, A Colasanti, DR Owen, M Onega, A Kamalakaran, I Bennacef, ...
Journal of nuclear medicine 54 (11), 1915-1923, 2013
1012013
A biomathematical modeling approach to central nervous system radioligand discovery and development
Q Guo, M Brady, RN Gunn
Journal of Nuclear Medicine 50 (10), 1715-1723, 2009
912009
Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo
Q Guo, DR Owen, EA Rabiner, FE Turkheimer, RN Gunn
Neuroimage 60 (2), 902-910, 2012
892012
Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs
RN Gunn, SG Summerfield, CA Salinas, KD Read, Q Guo, GE Searle, ...
Journal of Cerebral Blood Flow & Metabolism 32 (5), 874-883, 2012
682012
Decreased hippocampal translocator protein (18 kDa) expression in alcohol dependence: a [11C]PBR28 PET study
NJ Kalk, Q Guo, D Owen, R Cherian, D Erritzoe, A Gilmour, AS Ribeiro, ...
Translational psychiatry 7 (1), e996, 2017
642017
11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195
M Kobayashi, T Jiang, S Telu, SS Zoghbi, RN Gunn, EA Rabiner, ...
Journal of Cerebral Blood Flow & Metabolism, 0271678X17699223, 2017
632017
A Graphical Method to Compare the in vivo Binding Potential of PET Radioligands in the Absence of a Reference Region: Application to [11C]PBR28 and [18F …
Q Guo, DR Owen, EA Rabiner, FE Turkheimer, RN Gunn
Journal of Cerebral Blood Flow & Metabolism 34 (7), 1162-1168, 2014
382014
The impact of the rs6971 polymorphism in TSPO for quantification and study design
DR Owen, Q Guo, EA Rabiner, RN Gunn
Clinical and Translational Imaging 3 (6), 417-422, 2015
352015
Tilavonemab in early Alzheimer’s disease: results from a phase 2, randomized, double-blind study
H Florian, D Wang, SE Arnold, M Boada, Q Guo, Z Jin, H Zheng, ...
Brain, awad024, 2023
272023
Evidence of brain inflammation in patients with human T-lymphotropic virus type 1-associated myelopathy (HAM): a pilot, multimodal imaging study using 11C-PBR28 PET, MR T1 …
R Dimber, Q Guo, C Bishop, A Adonis, A Buckley, A Kocsis, D Owen, ...
J Nucl Med 57 (12), 1905-1912, 2016
242016
Deep learning based multimodal progression modeling for Alzheimer’s disease
L Yang, X Wang, Q Guo, S Gladstein, D Wooten, T Li, WZ Robieson, ...
Statistics in Biopharmaceutical Research 13 (3), 337-343, 2021
122021
A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18-F MK-6240 Positron Emission Tomography
JP Seibyl, JM DuBois, A Racine, J Collins, Q Guo, D Wooten, E Stage, ...
Journal of Nuclear Medicine, 2022
92022
Advances in biomathematical modeling for PET neuroreceptor imaging
RN Gunn, Q Guo, CA Salinas, AC Tziortzi, GE Searle
Drug Discovery Today: Technologies 8 (2-4), e45-e51, 2011
72011
Imaging of Mitochondrial Complex 1 with 18F-BCPP-EF in the Healthy Human Brain
A Mansur, R Comley, Y Lewis, L Middleton, M Huiban, Q Guo, J Passchier, ...
Journal of Nuclear Medicine 59 (supplement 1), 1709-1709, 2018
52018
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