Vivek Sharma
Vivek Sharma
University of Massachusetts Chan Med School, USA
Verifisert e-postadresse på umassmed.edu
Sitert av
Sitert av
Antisense oligonucleotides: modifications and clinical trials
VK Sharma, RK Sharma, SK Singh
MedChemComm 5 (10), 1454-1471, 2014
Synthesis, utility and medicinal importance of 1, 2-& 1, 4-dihydropyridines
VK Sharma, SK Singh
RSC advances 7 (5), 2682-2732, 2017
Oligonucleotide therapeutics: chemistry, delivery and clinical progress
VK Sharma, JK Watts
Future medicinal chemistry 7 (16), 2221-2242, 2015
Nucleic acid therapeutics: basic concepts and recent developments
VK Sharma, P Rungta, AK Prasad
RSC Advances 4 (32), 16618-16631, 2014
Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs’ dystrophy
J Hu, Z Rong, X Gong, Z Zhou, VK Sharma, C Xing, JK Watts, DR Corey, ...
Human molecular genetics 27 (6), 1015-1026, 2018
Synthesis and biological properties of triazole-linked locked nucleic acid
VK Sharma, SK Singh, PM Krishnamurthy, JF Alterman, RA Haraszti, ...
Chemical Communications 53 (63), 8906-8909, 2017
Activation of frataxin protein expression by antisense oligonucleotides targeting the mutant expanded repeat
L Li, X Shen, Z Liu, M Norrbom, TP Prakash, D O'Reilly, VK Sharma, ...
nucleic acid therapeutics 28 (1), 23-33, 2018
Novel cluster and monomer-based GalNAc structures induce effective uptake of siRNAs in vitro and in vivo
VK Sharma, MF Osborn, MR Hassler, D Echeverria, S Ly, EA Ulashchik, ...
Bioconjugate chemistry 29 (7), 2478-2488, 2018
Chemoenzymatic Convergent Synthesis of 2′-O,4′-C-Methyleneribonucleosides
VK Sharma, M Kumar, CE Olsen, AK Prasad
The Journal of organic chemistry 79 (13), 6336-6341, 2014
Locked nucleic acid gapmers and conjugates potently silence ADAM33, an asthma-associated metalloprotease with nuclear-localized mRNA
HM Pendergraff, PM Krishnamurthy, AJ Debacker, MP Moazami, ...
Molecular Therapy-Nucleic Acids 8, 158-168, 2017
Biocatalytic Deacylation Studies on Tetra-O-acyl-β-d-xylofuranosyl Nucleosides: Synthesis of xylo-LNA Monomers
SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad
The Journal of Organic Chemistry 76 (18), 7556-7562, 2011
Chemoenzymatic Synthesis of C-4′-Spiro-oxetanoribonucleosides
VK Sharma, M Kumar, D Sharma, CE Olsen, AK Prasad
The Journal of Organic Chemistry 79 (18), 8516-8521, 2014
Reactions of 1,2- & 1,4-dihydropyridines
SK Singh, VK Sharma
Curr Org Chem 18 (9), 1159-1207, 2014
Biocatalytic Separation of N-7/N-9 Guanine Nucleosides
SK Singh, VK Sharma, CE Olsen, J Wengel, VS Parmar, AK Prasad
The Journal of Organic Chemistry 75 (22), 7932-7935, 2010
Design and synthesis of LNA-based mercaptoacetamido-linked nucleoside dimers
VK Sharma, SK Singh, K Bohra, V Khatri, CE Olsen, AK Prasad
Nucleosides, Nucleotides and Nucleic Acids 32 (5), 256-272, 2013
Chemo-enzymatic synthesis of bicyclic 3′-azido-and 3′-amino-nucleosides
M Kumar, VK Sharma, CE Olsen, AK Prasad
RSC Advances 4 (70), 37231-37235, 2014
Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing
AJ Debacker, VK Sharma, P Meda Krishnamurthy, D O’Reilly, R Greenhill, ...
Biochemistry 58 (6), 582-589, 2019
Biocatalytic route to C-3′-azido/-hydroxy-C-4′-spiro-oxetanoribonucleosides
M Kumar, VK Sharma, R Kumar, AK Prasad
Carbohydrate research 417, 19-26, 2015
Synthesis of triazole-linked LNA-based non-ionic nucleoside dimers using Cu(I)-catalyzed ‘Click’ reaction
SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad
Curr. Org. Synth. 11 (5), 757-766, 2014
An astute synthesis of locked nucleic acid monomers
VK Sharma, P Rungta, VK Maikhuri, AK Prasad
Sustainable Chemical Processes 3, 1-6, 2015
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Artikler 1–20