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Alexander Grünberger
Alexander Grünberger
Professor for "Microsystems in Bioprocess engineering", Karlsruhe Institute of Technology (KIT)
Verifisert e-postadresse på kit.edu - Startside
Tittel
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År
The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids
N Mustafi, A Grünberger, D Kohlheyer, M Bott, J Frunzke
Metabolic engineering 14 (4), 449-457, 2012
2482012
Single-cell microfluidics: opportunity for bioprocess development
A Grünberger, W Wiechert, D Kohlheyer
Current opinion in biotechnology 29, 15-23, 2014
1882014
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 for use as a platform strain for basic research and industrial biotechnology
M Baumgart, S Unthan, C Rückert, J Sivalingam, A Grünberger, ...
Applied and environmental microbiology 79 (19), 6006-6015, 2013
1722013
Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways
G Schendzielorz, M Dippong, A Grunberger, D Kohlheyer, A Yoshida, ...
ACS synthetic biology 3 (1), 21-29, 2014
1642014
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level
A Grünberger, N Paczia, C Probst, G Schendzielorz, L Eggeling, S Noack, ...
Lab on a Chip 12 (11), 2060-2068, 2012
1322012
Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium
S Unthan, A Grünberger, J van Ooyen, J Gätgens, J Heinrich, N Paczia, ...
Biotechnology and bioengineering 111 (2), 359-371, 2014
1292014
Application of a genetically encoded biosensor for live cell imaging of L-valine production in pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum strains
N Mustafi, A Grünberger, R Mahr, S Helfrich, K Nöh, B Blombach, ...
PloS one 9 (1), e85731, 2014
1232014
Homogenizing bacterial cell factories: analysis and engineering of phenotypic heterogeneity
D Binder, T Drepper, KE Jaeger, F Delvigne, W Wiechert, D Kohlheyer, ...
Metabolic engineering 42, 145-156, 2017
1122017
Spatiotemporal microbial single‐cell analysis using a high‐throughput microfluidics cultivation platform
A Grünberger, C Probst, S Helfrich, A Nanda, B Stute, W Wiechert, ...
Cytometry Part A 87 (12), 1101-1115, 2015
1032015
A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments
A Burmeister, F Hilgers, A Langner, C Westerwalbesloh, Y Kerkhoff, ...
Lab on a Chip 19 (1), 98-110, 2019
962019
Enhanced protein and biochemical production using CRISPRi-based growth switches
S Li, CB Jendresen, A Grünberger, C Ronda, SI Jensen, S Noack, ...
Metabolic engineering 38, 274-284, 2016
912016
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments
A Grünberger, J van Ooyen, N Paczia, P Rohe, G Schiendzielorz, ...
Biotechnology and bioengineering 110 (1), 220-228, 2013
832013
Microfluidic picoliter bioreactor for microbial single-cell analysis: fabrication, system setup, and operation
A Gruenberger, C Probst, A Heyer, W Wiechert, J Frunzke, D Kohlheyer
JoVE (Journal of Visualized Experiments), e50560, 2013
822013
Microfluidics for biotechnology: bridging gaps to foster microfluidic applications
V Ortseifen, M Viefhues, L Wobbe, A Grünberger
Frontiers in Bioengineering and Biotechnology 8, 589074, 2020
812020
Analysis of SOS-induced spontaneous prophage induction in Corynebacterium glutamicum at the single-cell level
AM Nanda, A Heyer, C Krämer, A Grünberger, D Kohlheyer, J Frunzke
Journal of bacteriology 196 (1), 180-188, 2014
802014
Engineering and application of a biosensor with focused ligand specificity
D Della Corte, HL van Beek, F Syberg, M Schallmey, F Tobola, ...
Nature communications 11 (1), 4851, 2020
732020
Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures
A Burmeister, A Grünberger
Current opinion in biotechnology 62, 106-115, 2020
682020
Coarse-grained modeling of protein second osmotic virial coefficients: sterics and short-ranged attractions
A Grünberger, PK Lai, MA Blanco, CJ Roberts
The Journal of Physical Chemistry B 117 (3), 763-770, 2013
662013
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes
C Probst, A Grünberger, W Wiechert, D Kohlheyer
Journal of microbiological methods 95 (3), 470-476, 2013
622013
Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG
D Binder, A Grünberger, A Loeschcke, C Probst, C Bier, J Pietruszka, ...
Integrative biology 6 (8), 755-765, 2014
592014
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Artikler 1–20