Antitumor activity of Dioscorea bulbifera L. rhizome in vivo JM Wang, LL Ji, CJ Branford-White, ZY Wang, KK Shen, H Liu, ZT Wang Fitoterapia 83 (2), 388-394, 2012 | 102 | 2012 |
Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathways K Shen, L Ji, C Gong, Y Ma, L Yang, Y Fan, M Hou, Z Wang Biochemical pharmacology 84 (6), 784-792, 2012 | 90 | 2012 |
Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade K Shen, L Ji, B Lu, C Xu, C Gong, G Morahan, Z Wang Chemico-biological interactions 218, 99-106, 2014 | 56 | 2014 |
Eukaryotic elongation factor 2 kinase promotes angiogenesis in hepatocellular carcinoma via PI3K/Akt and STAT3 Y Zhou, Y Li, S Xu, J Lu, Z Zhu, S Chen, Y Tan, P He, J Xu, CG Proud, ... International journal of cancer 146 (5), 1383-1395, 2020 | 47 | 2020 |
Cambogin induces caspase-independent apoptosis through the ROS/JNK pathway and epigenetic regulation in breast cancer cells. K Shen, J Xie, H Wang, Z Hong, Y Mengyuan, L Fangfang, T Hongsheng, ... Molecular Cancer Therapeutics 14 (7), 1738-1749, 2015 | 45 | 2015 |
Critical roles of cellular glutathione homeostasis and JNK activation in andrographolide‐mediated apoptotic cell death in human hepatoma cells L Ji, K Shen, P Jiang, G Morahan, Z Wang Molecular Carcinogenesis 50 (8), 580-591, 2011 | 40 | 2011 |
Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis J Xie, K Shen, RV Lenchine, LA Gethings, PJ Trim, MF Snel, Y Zhou, ... International journal of cancer 142 (9), 1865-1877, 2018 | 37 | 2018 |
Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1 K Shen, Z Xi, J Xie, H Wang, C Xie, CS Lee, P Fahey, Q Dong, H Xu Oncotarget 7 (35), 56650, 2016 | 35 | 2016 |
Influence of glutathione levels and activity of glutathione-related enzymes in the brains of tumor-bearing mice K Shen, L Ji, Y Chen, Q Yu, Z Wang Bioscience trends 5 (1), 30-37, 2011 | 34 | 2011 |
Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries K Shen, SWS Leung, L Ji, Y Huang, M Hou, A Xu, Z Wang, PM Vanhoutte Biochemical Pharmacology 88 (1), 66-74, 2014 | 33 | 2014 |
Andrographolide inhibits hepatoma cells growth and affects the expression of cell cycle related proteins. KK Shen, TY Liu, C Xu, LL Ji, ZT Wang Yao xue xue bao= Acta Pharmaceutica Sinica 44 (9), 973-979, 2009 | 25 | 2009 |
Critical role of c-Jun N-terminal kinase in regulating bFGF-induced angiogenesis in vitro S Kaikai, S Yuchen, J Lili, W Zhengtao The journal of biochemistry 150 (2), 189-197, 2011 | 23 | 2011 |
c-Jun N-terminal kinase mediated VEGFR2 sustained phosphorylation is critical for VEGFA-induced angiogenesis in vitro and in vivo K Shen, L Ji, B Lu, Z Wang Cell biochemistry and biophysics 64, 17-27, 2012 | 21 | 2012 |
Intracellular glutathione regulates Andrographolide-induced cytotoxicity on hepatoma Hep3B cells L Ji, K Shen, J Liu, Y Chen, T Liu, Z Wang Redox Report 14 (4), 176-184, 2009 | 21 | 2009 |
Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology … K Shen, F Lu, J Xie, M Wu, B Cai, Y Liu, H Zhang, H Tan, Y Pan, H Xu Oncotarget 7 (31), 50596, 2016 | 20 | 2016 |
Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis J Xie, K Shen, AT Jones, J Yang, AR Tee, MH Shen, M Yu, S Irani, ... Cellular and Molecular Life Sciences 78, 249-270, 2021 | 18 | 2021 |
Involvement of c‐Jun N‐terminal kinase and extracellular signal‐regulated kinase 1/2 in EGF‐induced angiogenesis K Shen, Y Sheng, L Ji, Z Wang Cell biology international 34 (12), 1213-1218, 2010 | 18 | 2010 |
Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα S Xu, X Qiao, P Peng, Z Zhu, Y Li, M Yu, L Chen, Y Cai, J Xu, X Shi, ... Frontiers in Pharmacology 13, 847483, 2022 | 10 | 2022 |
Da Chaihutang Inhibits Hepatocellular Carcinoma by Regulating p38 MAPK/IL-6/STAT3 Signaling Pathway X QIAO, S XU, Y WANG, B FENG, P PENG, K SHEN Chinese Journal of Experimental Traditional Medical Formulae, 19-28, 2022 | 2 | 2022 |
Usage of guttiferone k for treating high metastatic cancer XU Hongxi, S Kaikai, LAO Yuanzhi, TAN Hongsheng, K Chen, D Yang, ... US Patent App. 14/701,529, 2015 | 2 | 2015 |