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Angelika Doetzlhofer
Angelika Doetzlhofer
Associate Professor, Johns Hopkins University School of Medicine
Verified email at jhmi.edu - Homepage
Title
Cited by
Cited by
Year
Histone deacetylase 1 can repress transcription by binding to Sp1
A Doetzlhofer, H Rotheneder, G Lagger, M Koranda, V Kurtev, G Brosch, ...
Molecular and cellular biology 19 (8), 5504-5511, 1999
5021999
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
PM White, A Doetzlhofer, YS Lee, AK Groves, N Segil
Nature 441 (7096), 984-987, 2006
4812006
Math1-driven GFP expression in the developing nervous system of transgenic mice
EA Lumpkin, T Collisson, P Parab, A Omer-Abdalla, H Haeberle, P Chen, ...
Gene Expression Patterns 3 (4), 389-395, 2003
3232003
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
A Doetzlhofer, ML Basch, T Ohyama, M Gessler, AK Groves, N Segil
Developmental cell 16 (1), 58-69, 2009
2672009
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
G Lagger, A Doetzlhofer, B Schuettengruber, E Haidweger, E Simboeck, ...
Molecular and cellular biology 23 (8), 2669-2679, 2003
2532003
In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme
A Doetzlhofer, PM White, JE Johnson, N Segil, AK Groves
Developmental biology 272 (2), 432-447, 2004
1252004
p19Ink4d and p21Cip1 collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis
H Laine, A Doetzlhofer, J Mantela, J Ylikoski, M Laiho, MF Roussel, ...
Journal of Neuroscience 27 (6), 1434-1444, 2007
1062007
Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea
S Korrapati, I Roux, E Glowatzki, A Doetzlhofer
PloS one 8 (8), e73276, 2013
892013
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates
ML Basch, RM Brown, HI Jen, F Semerci, F Depreux, RK Edlund, H Zhang, ...
Elife 5, e19921, 2016
732016
Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling
A Benito-Gonzalez, A Doetzlhofer
Journal of Neuroscience 34 (38), 12865-12876, 2014
592014
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
PQ Duy, SC Weise, C Marini, XJ Li, D Liang, PJ Dahl, S Ma, A Spajic, ...
Nature neuroscience 25 (4), 458-473, 2022
502022
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea
EJ Golden, A Benito-Gonzalez, A Doetzlhofer
Proceedings of the National Academy of Sciences 112 (29), E3864-E3873, 2015
462015
LIN28B/ let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling
XJ Li, A Doetzlhofer
Proc Natl Acad Sci U S A . 117 (36), 22225-22236, 2020
422020
Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea
A Doetzlhofer, P White, YS Lee, A Groves, N Segil
Brain research 1091 (1), 282-288, 2006
412006
Insights into inner ear-specific gene regulation: Epigenetics and non-coding RNAs in inner ear development and regeneration
A Doetzlhofer, KB Avraham
Seminars in cell & developmental biology 65, 69-79, 2017
402017
Alternate Activation of Two Divergently Transcribed Mouse Genes from a Bidirectional Promoter Is Linked to Changes in Histone Modification
B Schuettengruber, A Doetzlhofer, K Kroboth, E Wintersberger, C Seiser
Journal of Biological Chemistry 278 (3), 1784-1793, 2003
332003
Canonical Notch signaling plays an instructive role in auditory supporting cell development
DP Campbell, E Chrysostomou, A Doetzlhofer
Scientific reports 6 (1), 19484, 2016
272016
Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
XJ Li, C Morgan, LA Goff, A Doetzlhofer
Science Advances 8 (6), eabj7651, 2022
262022
Growth-regulated antisense transcription of the mouse thymidine kinase gene
H Sutterluety, B Stefan, A Doetzlhofer, H Khier, E Wintersberger, C Seiser
Nucleic acids research 26 (21), 4989-4995, 1998
231998
A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
M Prajapati-DiNubila, A Benito-Gonzalez, EJ Golden, S Zhang, ...
Elife 8, e47613, 2019
202019
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