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David T Humphreys
David T Humphreys
Research Scientist, Bioinformatician
Verifisert e-postadresse på victorchang.edu.au
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Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
A Castello, B Fischer, K Eichelbaum, R Horos, BM Beckmann, C Strein, ...
Cell 149 (6), 1393-1406, 2012
21702012
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA
JE Squires, HR Patel, M Nousch, T Sibbritt, DT Humphreys, BJ Parker, ...
Nucleic acids research 40 (11), 5023-5033, 2012
9772012
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly (A) tail function
DT Humphreys, BJ Westman, DIK Martin, T Preiss
Proceedings of the National Academy of Sciences 102 (47), 16961-16966, 2005
9422005
Clusterin has chaperone-like activity similar to that of small heat shock proteins
DT Humphreys, JA Carver, SB Easterbrook-Smith, MR Wilson
Journal of Biological Chemistry 274 (11), 6875-6881, 1999
5431999
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells
CCY Li, SA Eaton, PE Young, M Lee, R Shuttleworth, DT Humphreys, ...
RNA biology 10 (8), 1333-1344, 2013
2742013
Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-β
N Schonrock, YD Ke, D Humphreys, M Staufenbiel, LM Ittner, T Preiss, ...
PloS one 5 (6), e11070, 2010
2592010
NAD deficiency, congenital malformations, and niacin supplementation
H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ...
New England Journal of Medicine 377 (6), 544-552, 2017
2342017
Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β
N Schonrock, DT Humphreys, T Preiss, J Götz
Journal of Molecular Neuroscience 46, 324-335, 2012
1772012
Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity
JE Cropley, SA Eaton, A Aiken, PE Young, E Giannoulatou, JWK Ho, ...
Molecular metabolism 5 (8), 699-708, 2016
1702016
microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells
TH Beilharz, DT Humphreys, JL Clancy, R Thermann, DIK Martin, ...
PloS one 4 (8), e6783, 2009
1472009
The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells
SP Keam, PE Young, AL McCorkindale, THY Dang, JL Clancy, ...
Nucleic acids research 42 (14), 8984-8995, 2014
1462014
Effects of clusterin overexpression on TNFα-and TGFβ-mediated death of L929 cells
D Humphreys, TT Hochgrebe, SB Easterbrook-Smith, MP Tenniswood, ...
Biochemistry 36 (49), 15233-15243, 1997
1041997
Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function
DT Humphreys, CJ Hynes, HR Patel, GH Wei, L Cannon, D Fatkin, ...
PloS one 7 (2), e30933, 2012
1032012
Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
V Janbandhu, V Tallapragada, R Patrick, Y Li, D Abeygunawardena, ...
Cell Stem Cell 29 (2), 281-297. e12, 2022
1022022
Verification and validation of bioinformatics software without a gold standard: a case study of BWA and Bowtie
E Giannoulatou, SH Park, DT Humphreys, JWK Ho
BMC bioinformatics 15, 1-8, 2014
892014
Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis
B Liang, M Soka, AH Christensen, MS Olesen, AP Larsen, FK Knop, ...
Journal of Molecular and Cellular Cardiology 67, 69-76, 2014
792014
A screening approach to identify clinically actionable variants causing congenital heart disease in exome data
JO Szot, H Cuny, GM Blue, DT Humphreys, E Ip, K Harrison, GF Sholler, ...
Circulation: Genomic and Precision Medicine 11 (3), e001978, 2018
782018
Modes of L929 cell death induced by TNF-α and other cytotoxic agents
DT Humphreys, MR Wilson
Cytokine 11 (10), 773-782, 1999
771999
Identification of clinically actionable variants from genome sequencing of families with congenital heart disease
D Alankarage, E Ip, JO Szot, J Munro, GM Blue, K Harrison, H Cuny, ...
Genetics in Medicine 21 (5), 1111-1120, 2019
722019
Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data
R Patrick, DT Humphreys, V Janbandhu, A Oshlack, JWK Ho, RP Harvey, ...
Genome biology 21, 1-27, 2020
682020
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Artikler 1–20