Frank Skorpen
Frank Skorpen
Institutt for Klinisk og Molekylær Medisin, NTNU
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A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
RJ Hung, JD McKay, V Gaborieau, P Boffetta, M Hashibe, D Zaridze, ...
Nature 452 (7187), 633-637, 2008
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
PA Aas, M Otterlei, PØ Falnes, CB Vågbø, F Skorpen, M Akbari, ...
Nature 421 (6925), 859-863, 2003
Lung cancer susceptibility locus at 5p15. 33
JD McKay, RJ Hung, V Gaborieau, P Boffetta, A Chabrier, G Byrnes, ...
Nature genetics 40 (12), 1404-1406, 2008
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
MT Landi, N Chatterjee, K Yu, LR Goldin, AM Goldstein, M Rotunno, ...
The american journal of human genetics 85 (5), 679-691, 2009
Base excision repair of DNA in mammalian cells
HE Krokan, H Nilsen, F Skorpen, M Otterlei, G Slupphaug
FEBS letters 476 (1-2), 73-77, 2000
The 118 A> G polymorphism in the human µ‐opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
P Klepstad, TT Rakvåg, S Kaasa, M Holthe, O Dale, PC Borchgrevink, ...
Acta Anaesthesiologica Scandinavica 48 (10), 1232-1239, 2004
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients
TT Rakvåg, P Klepstad, C Baar, TM Kvam, O Dale, S Kaasa, HE Krokan, ...
Pain 116 (1-2), 73-78, 2005
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
H Nilsen, M Otterlei, T Haug, K Solum, TA Nagelhus, F Skorpen, ...
Nucleic acids research 25 (4), 750-755, 1997
hUNG2 is the major repair enzyme for removal of uracil from U: A matches, U: G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
B Kavli, O Sundheim, M Akbari, M Otterlei, H Nilsen, F Skorpen, PA Aas, ...
Journal of Biological Chemistry 277 (42), 39926-39936, 2002
Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
CC Reyes-Gibby, S Shete, T Rakvåg, SV Bhat, F Skorpen, E Bruera, ...
Pain 130 (1-2), 25-30, 2007
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
Y Wang, JD McKay, T Rafnar, Z Wang, MN Timofeeva, P Broderick, ...
Nature genetics 46 (7), 736-741, 2014
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
OL Holmen, H Zhang, Y Fan, DH Hovelson, EM Schmidt, W Zhou, Y Guo, ...
Nature genetics 46 (4), 345-351, 2014
Health care providers underestimate symptom intensities of cancer patients: a multicenter European study
EA Laugsand, MAG Sprangers, K Bjordal, F Skorpen, S Kaasa, ...
Health and quality of life outcomes 8 (1), 1-13, 2010
CUBN is a gene locus for albuminuria
CA Böger, MH Chen, A Tin, M Olden, A Köttgen, IH de Boer, ...
Journal of the American Society of Nephrology 22 (3), 555-570, 2011
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls
MN Timofeeva, RJ Hung, T Rafnar, DC Christiani, JK Field, H Bickeböller, ...
Human molecular genetics 21 (22), 4980-4995, 2012
Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients
P Klepstad, T Fladvad, F Skorpen, K Bjordal, A Caraceni, O Dale, ...
Pain 152 (5), 1139-1145, 2011
Investigation of the fine structure of European populations with applications to disease association studies
SC Heath, IG Gut, P Brennan, JD McKay, V Bencko, E Fabianova, ...
European Journal of Human Genetics 16 (12), 1413-1429, 2008
Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to …
M Holthe, TN Rakvåg, P Klepstad, JR Idle, S Kaasa, HE Krokan, ...
The pharmacogenomics journal 3 (1), 17-26, 2003
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A
TA Nagelhus, T Haug, KK Singh, KF Keshav, F Skorpen, M Otterlei, ...
Journal of Biological Chemistry 272 (10), 6561-6566, 1997
Genetic Variation in the Catechol-O-Methyltransferase (COMT) Gene and Morphine Requirements in Cancer Patients with Pain
TT Rakvåg, JR Ross, H Sato, F Skorpen, S Kaasa, P Klepstad
Molecular pain 4, 1744-8069-4-64, 2008
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