Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations Y Shi, NR Rhodes, A Abdolvahabi, T Kohn, NP Cook, AA Marti, BF Shaw Journal of the American Chemical Society 135 (42), 15897-15908, 2013 | 64 | 2013 |
Arresting amyloid with coulomb’s law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation A Abdolvahabi, Y Shi, NR Rhodes, NP Cook, AA Martí, BF Shaw Biophysical journal 108 (5), 1199-1212, 2015 | 54 | 2015 |
Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosis A Abdolvahabi, Y Shi, A Chuprin, S Rasouli, BF Shaw ACS chemical neuroscience 7 (6), 799-810, 2016 | 46 | 2016 |
Lysine acylation in superoxide dismutase-1 electrostatically inhibits formation of fibrils with prion-like seeding S Rasouli, A Abdolvahabi, CM Croom, DL Plewman, Y Shi, JI Ayers, ... Journal of Biological Chemistry 292 (47), 19366-19380, 2017 | 34 | 2017 |
How do gyrating beads accelerate amyloid fibrillization? A Abdolvahabi, Y Shi, S Rasouli, CM Croom, A Chuprin, BF Shaw Biophysical Journal 112 (2), 250-264, 2017 | 33 | 2017 |
Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma A Abdolvahabi, BW Taylor, RL Holden, EV Shaw, A Kentsis, ... PloS one 8 (10), e76677, 2013 | 32 | 2013 |
Gibbs energy of superoxide dismutase heterodimerization accounts for variable survival in amyotrophic lateral sclerosis Y Shi, MJ Acerson, A Abdolvahabi, RA Mowery, BF Shaw Journal of the American Chemical Society 138 (16), 5351-5362, 2016 | 25 | 2016 |
Protein charge ladders reveal that the net charge of ALS‐linked superoxide dismutase can be different in sign and magnitude from predicted values Y Shi, A Abdolvahabi, BF Shaw Protein Science 23 (10), 1417-1433, 2014 | 23 | 2014 |
Kaplan–Meier meets chemical kinetics: intrinsic rate of SOD1 amyloidogenesis decreased by subset of ALS mutations and cannot fully explain age of disease onset A Abdolvahabi, Y Shi, S Rasouli, CM Croom, A Aliyan, AA Martí, BF Shaw ACS Chemical Neuroscience 8 (6), 1378-1389, 2017 | 22 | 2017 |
Targeting KDM4 for treating PAX3-FOXO1–driven alveolar rhabdomyosarcoma S Singh, A Abu-Zaid, H Jin, J Fang, Q Wu, T Wang, H Feng, W Quarni, ... Science translational medicine 14 (653), eabq2096, 2022 | 18 | 2022 |
Direct measurement of charge regulation in metalloprotein electron transfer CT Zahler, H Zhou, A Abdolvahabi, RL Holden, S Rasouli, P Tao, ... Angewandte Chemie 130 (19), 5462-5466, 2018 | 16 | 2018 |
Metal-ion-specific screening of charge effects in protein amide H/D exchange and the Hofmeister series A Abdolvahabi, JL Gober, RA Mowery, Y Shi, BF Shaw Analytical chemistry 86 (20), 10303-10310, 2014 | 13 | 2014 |
Bacteriophage antidefense genes that neutralize TIR and STING immune responses P Ho, Y Chen, S Biswas, E Canfield, A Abdolvahabi, DE Feldman Cell Reports 42 (4), 2023 | 11 | 2023 |
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma S Singh, A Abu-Zaid, W Lin, J Low, A Abdolvahabi, H Jin, Q Wu, B Cooke, ... Iscience 24 (1), 2021 | 8 | 2021 |
Protein Misfolding Diseases CM Gomes Humana Press, 2019 | 6 | 2019 |
Glycerolipid headgroups control rate and mechanism of superoxide dismutase-1 aggregation and accelerate fibrillization of slowly aggregating amyotrophic lateral sclerosis mutants S Rasouli, A Abdolvahabi, CM Croom, DL Plewman, Y Shi, BF Shaw ACS Chemical Neuroscience 9 (7), 1743-1756, 2018 | 5 | 2018 |
Site-specific antibody-drug conjugates with variable drug-to-antibody-ratios for AML therapy Z Dai, XN Zhang, Q Cheng, F Fei, T Hou, J Li, A Abdolvahabi, J Watanabe, ... Journal of Controlled Release 336, 433-442, 2021 | 4 | 2021 |
Measuring how two proteins affect each other's net charge in a crowded environment CM Dashnaw, JC Koone, A Abdolvahabi, BF Shaw Protein Science 30 (8), 1594-1605, 2021 | 3 | 2021 |
The growing landscape of metabolomics and lipidomics: applications to medicinal chemistry and drug discovery G Palacios, JJ Bowling, A Abdolvahabi Future medicinal chemistry 11 (6), 495-498, 2019 | 3 | 2019 |
Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize … PJ Slavish, MG Cuypers, MA Rimmer, A Abdolvahabi, T Jeevan, G Kumar, ... European Journal of Medicinal Chemistry 247, 115035, 2023 | 2 | 2023 |