| Lipid metabolism reprogramming and its potential targets in cancer C Cheng, F Geng, X Cheng, D Guo Cancer communications 38, 1-14, 2018 | 537 | 2018 |
| An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR–dependent pathway D Guo, F Reinitz, M Youssef, C Hong, D Nathanson, D Akhavan, D Kuga, ... Cancer discovery 1 (5), 442-456, 2011 | 444 | 2011 |
| EGFR signaling through an Akt-SREBP-1–dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy D Guo, RM Prins, J Dang, D Kuga, A Iwanami, H Soto, KY Lin, TT Huang, ... Science signaling 2 (101), ra82-ra82, 2009 | 359 | 2009 |
| Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells Q Shi, L Qin, W Wei, F Geng, R Fan, Y Shik Shin, D Guo, L Hood, ... Proceedings of the National Academy of Sciences 109 (2), 419-424, 2012 | 354 | 2012 |
| Oncogenic EGFR signaling activates an mTORC2–NF-κB pathway that promotes chemotherapy resistance K Tanaka, I Babic, D Nathanson, D Akhavan, D Guo, B Gini, J Dang, ... Cancer discovery 1 (6), 524-538, 2011 | 332 | 2011 |
| Targeting SREBP-1-driven lipid metabolism to treat cancer D Guo, E Hlavin Bell, P Mischel, A Chakravarti Current pharmaceutical design 20 (15), 2619-2626, 2014 | 284 | 2014 |
| Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway M Atefi, E von Euw, N Attar, C Ng, C Chu, D Guo, R Nazarian, ... PloS one 6 (12), e28973, 2011 | 276 | 2011 |
| Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific Raf inhibitor PLX4032 JN Søndergaard, R Nazarian, Q Wang, D Guo, T Hsueh, S Mok, ... Journal of translational medicine 8, 1-11, 2010 | 272 | 2010 |
| The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis D Guo, IJ Hildebrandt, RM Prins, H Soto, MM Mazzotta, J Dang, J Czernin, ... Proceedings of the National Academy of Sciences 106 (31), 12932-12937, 2009 | 263 | 2009 |
| Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ... Clinical Cancer Research 22 (21), 5337-5348, 2016 | 255 | 2016 |
| Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ... Cancer cell 28 (5), 569-581, 2015 | 237 | 2015 |
| Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo D Ai, Y Fu, D Guo, H Tanaka, N Wang, C Tang, BD Hammock, JYJ Shyy, ... Proceedings of the National Academy of Sciences 104 (21), 9018-9023, 2007 | 188 | 2007 |
| Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress X Cheng, F Geng, M Pan, X Wu, Y Zhong, C Wang, Z Tian, C Cheng, ... Cell metabolism 32 (2), 229-242. e8, 2020 | 178 | 2020 |
| Lipid metabolism emerges as a promising target for malignant glioma therapy Deliang Guo, Erica Hlavin Bell, Arnab Chakravarti CNS Oncology 2 (3), 289-299, 2013 | 177 | 2013 |
| EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer I Babic, ES Anderson, K Tanaka, D Guo, K Masui, B Li, S Zhu, Y Gu, ... Cell metabolism 17 (6), 1000-1008, 2013 | 168 | 2013 |
| Regulation of endothelial cell cycle by laminar versus oscillatory flow: distinct modes of interactions of AMP-activated protein kinase and Akt pathways D Guo, S Chien, JYJ Shyy Circulation research 100 (4), 564-571, 2007 | 126 | 2007 |
| Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations F Niehr, E von Euw, N Attar, D Guo, D Matsunaga, H Sazegar, C Ng, ... Journal of translational medicine 9, 1-13, 2011 | 114 | 2011 |
| SCAP/SREBPs are central players in lipid metabolism and novel metabolic targets in cancer therapy X Cheng, J Li, D Guo Current topics in medicinal chemistry 18 (6), 484-493, 2018 | 110 | 2018 |
| Tumor metabolism of malignant gliomas P Ru, TM Williams, A Chakravarti, D Guo Cancers 5 (4), 1469-1484, 2013 | 89 | 2013 |
| Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell reports 16 (6), 1527-1535, 2016 | 83 | 2016 |
