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Saul Martinez-Montero
Saul Martinez-Montero
Verifisert e-postadresse på its.jnj.com
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Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
YM Abbas, BT Laudenbach, S Martínez-Montero, R Cencic, M Habjan, ...
Proceedings of the National Academy of Sciences 114 (11), E2106-E2115, 2017
1062017
Antibody-antisense oligonucleotide conjugate downregulates a key gene in glioblastoma stem cells
AE Arnold, E Malek-Adamian, PU Le, A Meng, S Martínez-Montero, ...
Molecular Therapy-Nucleic Acids 11, 518-527, 2018
682018
Locked 2′-deoxy-2′, 4′-difluororibo modified nucleic acids: thermal stability, structural studies, and siRNA activity
S Martinez-Montero, GF Deleavey, N Martin-Pintado, JF Fakhoury, ...
ACS chemical biology 10 (9), 2016-2023, 2015
592015
4′-C-Methoxy-2′-deoxy-2′-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing
E Malek-Adamian, DC Guenther, S Matsuda, S Martínez-Montero, I Zlatev, ...
Journal of the American Chemical Society 139 (41), 14542-14555, 2017
562017
Rigid 2′, 4′-difluororibonucleosides: synthesis, conformational analysis, and incorporation into nascent RNA by HCV polymerase
S Martinez-Montero, GF Deleavey, A Kulkarni, N Martín-Pintado, ...
The Journal of Organic Chemistry 79 (12), 5627-5635, 2014
532014
Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′, 3′-dideoxy-2′, 2′-difluoro-4′-azanucleosides
S Martínez-Montero, S Fernández, YS Sanghvi, EA Theodorakis, ...
Bioorganic & medicinal chemistry 20 (23), 6885-6893, 2012
422012
Synthesis and properties of 2′-deoxy-2′, 4′-difluoroarabinose-modified nucleic acids
S Martínez-Montero, GF Deleavey, A Dierker-Viik, P Lindovska, T Ilina, ...
The Journal of organic chemistry 80 (6), 3083-3091, 2015
372015
Adjusting the structure of 2′-modified nucleosides and oligonucleotides via C4′-α-F or C4′-α-OMe substitution: synthesis and conformational analysis
E Malek-Adamian, MB Patrascu, SK Jana, S Martínez-Montero, ...
The Journal of Organic Chemistry 83 (17), 9839-9849, 2018
342018
Design and divergent synthesis of aza nucleosides from a chiral imino sugar
S Martı́nez-Montero, S Fernández, YS Sanghvi, J Chattopadhyaya, ...
The Journal of Organic Chemistry 77 (10), 4671-4678, 2012
262012
An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis
S Martínez-Montero, S Fernández, YS Sanghvi, V Gotor, M Ferrero
Organic & Biomolecular Chemistry 9 (17), 5960-5966, 2011
242011
Effect of sugar 2′, 4′-modifications on gene silencing activity of siRNA duplexes
E Malek-Adamian, J Fakhoury, AE Arnold, S Martínez-Montero, ...
nucleic acid therapeutics 29 (4), 187-194, 2019
202019
Nucleotide sugar pucker preference mitigates excision by HIV-1 RT
K Yamada, AS Wahba, JA Bernatchez, T Ilina, S Martínez-Montero, ...
ACS chemical biology 10 (9), 2024-2033, 2015
142015
Enzymatic Parallel Kinetic Resolution of Mixtures of d/l 2′-Deoxy and Ribonucleosides: An Approach for the Isolation of β-l-Nucleosides
S Martínez-Montero, S Fernández, YS Sanghvi, V Gotor, M Ferrero
The Journal of Organic Chemistry 75 (19), 6605-6613, 2010
142010
Seven-membered ring nucleoside analogues: Stereoselective synthesis and studies on their conformational properties
M Habibian, S Martinez-Montero, G Portella, Z Chua, DS Bohle, M Orozco, ...
Organic letters 17 (21), 5416-5419, 2015
122015
Improved Synthesis and Isolation of 2′‐O‐Methyladenosine: Effective and Scalable Enzymatic Separation of 2′/3′‐O‐Methyladenosine Regioisomers
S Martínez‐Montero, S Fernández, T Rodríguez‐Pérez, YS Sanghvi, ...
European Journal of Organic Chemistry 2009 (19), 3265-3271, 2009
122009
Carrier-free gene silencing by amphiphilic nucleic acid conjugates in differentiated intestinal cells
E Moroz, SH Lee, K Yamada, F Halloy, S Martínez-Montero, H Jahns, ...
Molecular Therapy-Nucleic Acids 5, 2016
112016
CAL‐B‐catalyzed acylation of nucleosides and role of the sugar conformation: an improved understanding of the enzyme‐substrate recognition
S Martínez‐Montero, S Fernández, YS Sanghvi, V Gotor, M Ferrero
European Journal of Organic Chemistry 2012 (28), 5483-5490, 2012
72012
Chemoenzymatic Synthesis of 3′‐O‐Acetal‐Protected 2′‐Deoxynucleosides as Building Blocks for Nucleic Acid Chemistry
T Rodríguez‐Pérez, S Fernández, S Martínez‐Montero, ...
European Journal of Organic Chemistry 2010 (9), 1736-1744, 2010
62010
A conserved homo-dimerization interface in human IFIT1 provides insights into IFIT interactome assembly
YM Abbas, S Martínez-Montero, R Cencic, J Pelletier, PD Pawelek, ...
bioRxiv, 152850, 2017
22017
Synthesis, Structure, and Conformational Analysis of Nucleoside Analogues Comprising Six‐Membered 1, 3‐Oxathiane Sugar Rings
H Abou Assi, S Martínez‐Montero, DM Dixit, Z Chua, DS Bohle, ...
European Journal of Organic Chemistry 2015 (9), 1945-1953, 2015
12015
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Artikler 1–20