| Mutational dynamics between primary and relapse neuroblastomas A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ... Nature genetics 47 (8), 872-877, 2015 | 368 | 2015 |
| Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ... Nature genetics 52 (9), 891-897, 2020 | 297 | 2020 |
| Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma RP Koche, E Rodriguez-Fos, K Helmsauer, M Burkert, IC MacArthur, ... Nature genetics 52 (1), 29-34, 2020 | 236 | 2020 |
| Targeting MYCN-driven transcription by BET-bromodomain inhibition A Henssen, K Althoff, A Odersky, A Beckers, R Koche, F Speleman, ... Clinical Cancer Research 22 (10), 2470-2481, 2016 | 180 | 2016 |
| BET bromodomain protein inhibition is a therapeutic option for medulloblastoma A Henssen, T Thor, A Odersky, L Heukamp, N El-Hindy, A Beckers, ... Oncotarget 4 (11), 2080, 2013 | 173 | 2013 |
| ecDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021 | 144 | 2021 |
| Current and future treatment strategies for rhabdomyosarcoma C Chen, H Dorado Garcia, M Scheer, AG Henssen Frontiers in oncology 9, 1458, 2019 | 132 | 2019 |
| Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma K Helmsauer, ME Valieva, S Ali, R Chamorro González, R Schöpflin, ... Nature communications 11 (1), 5823, 2020 | 124 | 2020 |
| TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets B Decaesteker, G Denecker, C Van Neste, EM Dolman, W Van Loocke, ... Nature communications 9 (1), 4866, 2018 | 89 | 2018 |
| PGBD5 promotes site-specific oncogenic mutations in human tumors AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ... Nature genetics 49 (7), 1005-1014, 2017 | 87 | 2017 |
| Genomic DNA transposition induced by human PGBD5 AG Henssen, E Henaff, E Jiang, AR Eisenberg, JR Carson, CM Villasante, ... Elife 4, e10565, 2015 | 85 | 2015 |
| Cytoarchitecture and probability maps of the human medial orbitofrontal cortex A Henssen, K Zilles, N Palomero-Gallagher, A Schleicher, H Mohlberg, ... Cortex 75, 87-112, 2016 | 84 | 2016 |
| Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors AG Henssen, C Reed, E Jiang, HD Garcia, J von Stebut, IC MacArthur, ... Science translational medicine 9 (414), eaam9078, 2017 | 60 | 2017 |
| Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma I Roeschert, E Poon, AG Henssen, H Dorado Garcia, M Gatti, C Giansanti, ... Nature cancer 2 (3), 312-326, 2021 | 59 | 2021 |
| The evolutionary dynamics of extrachromosomal DNA in human cancers JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ... Nature genetics 54 (10), 1527-1533, 2022 | 56 | 2022 |
| CD171-and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing L Andersch, J Radke, A Klaus, S Schwiebert, A Winkler, E Schumann, ... BMC cancer 19, 1-17, 2019 | 55 | 2019 |
| Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing C Stangl, S de Blank, I Renkens, L Westera, T Verbeek, JE Valle-Inclan, ... Nature Communications 11 (1), 2861, 2020 | 52 | 2020 |
| Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH KL Hung, J Luebeck, SR Dehkordi, CI Colón, R Li, ITL Wong, C Coruh, ... Nature genetics 54 (11), 1746-1754, 2022 | 50 | 2022 |
| Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions K Schmelz, J Toedling, M Huska, MC Cwikla, LM Kruetzfeldt, J Proba, ... Nature communications 12 (1), 6804, 2021 | 48 | 2021 |
| Extrachromosomal DNA amplifications in cancer E Yi, R Chamorro González, AG Henssen, RGW Verhaak Nature Reviews Genetics 23 (12), 760-771, 2022 | 45 | 2022 |
