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james mclarnon
james mclarnon
professor of pharmacology
Verified email at mail.ubc.ca
Title
Cited by
Cited by
Year
A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
JK Ryu, JG McLarnon
Journal of cellular and molecular medicine 13 (9a), 2911-2925, 2009
4442009
Upregulated Expression of Purinergic P2X7 Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus
JG McLarnon, JK Ryu, DG Walker, HB Choi
Journal of Neuropathology & Experimental Neurology 65 (11), 1090-1097, 2006
2922006
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase
HB Choi, GRJ Gordon, N Zhou, C Tai, RL Rungta, J Martinez, TA Milner, ...
Neuron 75 (6), 1094-1104, 2012
2712012
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease
JK Ryu, J Kim, SJ Cho, K Hatori, A Nagai, HB Choi, MC Lee, ...
Neurobiology of disease 16 (1), 68-77, 2004
2232004
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain
HB Choi, JK Ryu, SU Kim, JG McLarnon
Journal of Neuroscience 27 (18), 4957-4968, 2007
2102007
Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines
A Nagai, E Nakagawa, K Hatori, HB Choi, JG McLarnon, MA Lee, SU Kim
Neurobiology of disease 8 (6), 1057-1068, 2001
1802001
Minocycline inhibits neuronal death and glial activation induced by β‐amyloid peptide in rat hippocampus
JK Ryu, S Franciosi, P Sattayaprasert, SU Kim, JG McLarnon
Glia 48 (1), 85-90, 2004
1662004
Human neural stem cells: electrophysiological properties of voltage-gated ion channels
T Cho, JH Bae, HB Choi, SS Kim, JG McLarnon, H Suh-Kim, SU Kim, ...
Neuroreport 13 (11), 1447-1452, 2002
1622002
Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease
JK Ryu, JG McLarnon
Neuroreport 19 (17), 1715-1719, 2008
1472008
Oxygen radical‐induced neurotoxicity in spinal cord neuron cultures
M Michikawa, KT Lim, JG McLarnon, SU Kim
Journal of neuroscience research 37 (1), 62-70, 1994
1321994
Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease
S Franciosi, JK Ryu, Y Shim, A Hill, C Connolly, MR Hayden, ...
Neurobiology of disease 45 (1), 438-449, 2012
1312012
Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology
JK Ryu, T Cho, HB Choi, YT Wang, JG McLarnon
Journal of Neuroscience 29 (1), 3-13, 2009
1312009
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum
JK Ryu, HB Choi, JG McLarnon
Neurobiology of disease 20 (2), 550-561, 2005
1312005
Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase
JK Ryu, HB Choi, K Hatori, RL Heisel, SL Pelech, JG McLarnon, SU Kim
Journal of neuroscience research 72 (3), 352-362, 2003
1302003
Expression and function of the P2X7 receptor in rat C6 glioma cells
W Wei, JK Ryu, HB Choi, JG McLarnon
Cancer letters 260 (1-2), 79-87, 2008
1112008
IL-8 enhancement of amyloid-beta (Aβ1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia
S Franciosi, HB Choi, SU Kim, JG McLarnon
Journal of neuroimmunology 159 (1-2), 66-74, 2005
1052005
Amyloid β peptide-induced corpus callosum damage and glial activation in vivo
N Jantaratnotai, JK Ryu, SU Kim, JG McLarnon
Neuroreport 14 (11), 1429-1433, 2003
1022003
Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed AD brain
JK Ryu, T Cho, YT Wang, JG McLarnon
Journal of neuroinflammation 6, 1-9, 2009
982009
Inhibition of lipopolysaccharide‐induced cyclooxygenase‐2, tumor necrosis factor‐α and [Ca2+]i responses in human microglia by the peripheral benzodiazepine …
HB Choi, C Khoo, JK Ryu, E Van Breemen, SU Kim, JG McLarnon
Journal of neurochemistry 83 (3), 546-555, 2002
972002
Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer’s disease brain
JK Ryu, JG McLarnon
Neurobiology of disease 29 (2), 254-266, 2008
962008
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Articles 1–20