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Miles Nunn
Miles Nunn
Chief Scientific Officer, Akari Therapeutics
Verified email at akaritx.com
Title
Cited by
Cited by
Year
Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata
MA Nunn, A Sharma, GC Paesen, S Adamson, O Lissina, AC Willis, ...
The Journal of Immunology 174 (4), 2084-2091, 2005
2512005
The British river of the future: how climate change and human activity might affect two contrasting river ecosystems in England
AC Johnson, MC Acreman, MJ Dunbar, SW Feist, AM Giacomello, ...
Science of the Total Environment 407 (17), 4787-4798, 2009
1762009
Modelling the effect of temperature on the seasonal population dynamics of temperate mosquitoes
DA Ewing, CA Cobbold, BV Purse, MA Nunn, SM White
Journal of theoretical biology 400, 65-79, 2016
1732016
Structure of and influence of a tick complement inhibitor on human complement component 5
F Fredslund, NS Laursen, P Roversi, L Jenner, CLP Oliveira, JS Pedersen, ...
Nature immunology 9 (7), 753-760, 2008
1662008
Potential risks associated with the proposed widespread use of Tamiflu
AC Singer, MA Nunn, EA Gould, AC Johnson
Environmental Health Perspectives 115 (1), 102-106, 2007
1382007
Structural basis for therapeutic inhibition of complement C5
MM Jore, S Johnson, D Sheppard, NM Barber, YI Li, MA Nunn, H Elmlund, ...
Nature structural & molecular biology 23 (5), 378-386, 2016
1182016
In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata
NJ Hepburn, AS Williams, MA Nunn, JC Chamberlain-Banoub, J Hamer, ...
Journal of biological chemistry 282 (11), 8292-8299, 2007
1182007
Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury
CC Garcia, W Weston-Davies, RC Russo, LP Tavares, MA Rachid, ...
PloS one 8 (5), e64443, 2013
1042013
Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
J Salát, GC Paesen, P Řezáčová, M Kotsyfakis, Z Kovářová, M Šanda, ...
Biochemical Journal 429 (1), 103-112, 2010
892010
West Nile virus vector Culex modestus established in southern England
N Golding, MA Nunn, JM Medlock, BV Purse, AGC Vaux, SM Schäfer
Parasites & vectors 5, 1-5, 2012
872012
Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses
SG Preston, J Majtán, C Kouremenou, O Rysnik, LF Burger, ...
PLoS pathogens 9 (6), e1003450, 2013
802013
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice
M Huber-Lang, A Barratt-Due, SE Pischke, Ø Sandanger, PH Nilsson, ...
The Journal of Immunology 192 (11), 5324-5331, 2014
722014
The structure of OMCI, a novel lipocalin inhibitor of the complement system
P Roversi, O Lissina, S Johnson, N Ahmat, GC Paesen, K Ploss, ...
Journal of molecular biology 369 (3), 784-793, 2007
692007
Meeting report: risk assessment of Tamiflu use under pandemic conditions
AC Singer, BM Howard, AC Johnson, CJ Knowles, S Jackman, C Accinelli, ...
Environmental health perspectives 116 (11), 1563-1567, 2008
612008
Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans
A Barratt-Due, EB Thorgersen, JK Lindstad, A Pharo, O Lissina, ...
The Journal of Immunology 187 (9), 4913-4919, 2011
602011
Vasotab, a vasoactive peptide from horse fly Hybomitra bimaculata (Diptera, Tabanidae) salivary glands
P Takác, MA Nunn, J Mészáros, O Pechánová, N Vrbjar, P Vlasáková, ...
Journal of experimental biology 209 (2), 343-352, 2006
572006
Combined inhibition of complement (C5) and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis
A Barratt-Due, EB Thorgersen, K Egge, S Pischke, A Sokolov, ...
The Journal of Immunology 191 (2), 819-827, 2013
562013
Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury
P Roversi, B Ryffel, D Togbe, I Maillet, M Teixeira, N Ahmat, GC Paesen, ...
Journal of Biological Chemistry 288 (26), 18789-18802, 2013
542013
Identifying biotic interactions which drive the spatial distribution of a mosquito community
N Golding, MA Nunn, BV Purse
Parasites & vectors 8, 1-10, 2015
532015
An ion-channel modulator from the saliva of the brown ear tick has a highly modified Kunitz/BPTI structure
GC Paesen, C Siebold, ML Dallas, C Peers, K Harlos, PA Nuttall, ...
Journal of molecular biology 389 (4), 734-747, 2009
532009
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