Alexander Schramm
Alexander Schramm
University Hospital Essen
Verified email at - Homepage
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Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy
JH Schulte, S Lim, A Schramm, N Friedrichs, J Koster, R Versteeg, I Ora, ...
Cancer research 69 (5), 2065-2071, 2009
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ...
Nature 526 (7575), 700-704, 2015
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
JJ Molenaar, R Domingo-Fernández, ME Ebus, S Lindner, J Koster, ...
Nature genetics 44 (11), 1199-1206, 2012
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
MYCN regulates oncogenic MicroRNAs in neuroblastoma
JH Schulte, S Horn, T Otto, B Samans, LC Heukamp, UC Eilers, M Krause, ...
International journal of cancer 122 (3), 699-704, 2008
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification
S De Brouwer, K De Preter, C Kumps, P Zabrocki, M Porcu, ...
Clinical cancer research 16 (17), 4353-4362, 2010
Mutational dynamics between primary and relapse neuroblastomas
A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ...
Nature genetics 47 (8), 872-877, 2015
Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
JH Schulte, T Marschall, M Martin, P Rosenstiel, P Mestdagh, S Schlierf, ...
Nucleic acids research 38 (17), 5919-5928, 2010
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
K De Preter, J Vandesompele, P Heimann, N Yigit, S Beckman, ...
Genome biology 7 (9), 1-17, 2006
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ...
Science translational medicine 4 (141), 141ra91-141ra91, 2012
Biological effects of TrkA and TrkB receptor signaling in neuroblastoma
A Schramm, JH Schulte, K Astrahantseff, O Apostolov, V van Limpt, ...
Cancer letters 228 (1-2), 143-153, 2005
Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors
M Naumann, N Savitskaia, C Eilert, A Schramm, H Kalthoff, W Schmiegel
Gastroenterology 110 (4), 1215-1224, 1996
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
A Sprüssel, JH Schulte, S Weber, M Necke, K Händschke, T Thor, ...
Leukemia 26 (9), 2039-2051, 2012
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
P Mestdagh, E Fredlund, F Pattyn, A Rihani, T Van Maerken, J Vermeulen, ...
Oncogene 29 (24), 3583-3592, 2010
Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia
D Steinbach, A Schramm, A Eggert, M Onda, K Dawczynski, A Rump, ...
Clinical cancer research 12 (8), 2434-2441, 2006
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors
P Mestdagh, E Fredlund, F Pattyn, JH Schulte, D Muth, J Vermeulen, ...
Oncogene 29 (9), 1394-1404, 2010
The Phox2B homeobox gene is mutated in sporadic neuroblastomas
V van Limpt, A Schramm, A Lakeman, P van Sluis, A Chan, M van Noesel, ...
Oncogene 23 (57), 9280-9288, 2004
Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
A Schramm, JH Schulte, L Klein-Hitpass, W Havers, H Sieverts, ...
Oncogene 24 (53), 7902-7912, 2005
BET bromodomain protein inhibition is a therapeutic option for medulloblastoma
A Henssen, T Thor, A Odersky, L Heukamp, N El-Hindy, A Beckers, ...
Oncotarget 4 (11), 2080, 2013
Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
C Grasemann, S Gratias, H Stephan, A Schüler, A Schramm, ...
Oncogene 24 (42), 6441-6449, 2005
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