Gavin Williams

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Medforfattere

Jon S. ThorsonProfessor and Associate Dean of Research, University of Kentucky College of PharmacyVerifisert e-postadresse på uky.edu
Adam NelsonProfessor of Chemical Biology, University of LeedsVerifisert e-postadresse på leeds.ac.uk
John B. McArthurResearch Scientist, IMCSVerifisert e-postadresse på ucdavis.edu
Changsheng ZhangProfessor of Marine Chemical Microbiology, South China Sea Institute of OceanologyVerifisert e-postadresse på scsio.ac.cn
Richard GanttDupont Industrial BiosciencesVerifisert e-postadresse på wisc.edu
David MuddimanNorth Carolina State UniversityVerifisert e-postadresse på ncsu.edu
Tilmann WeberProfessor / Co-PI @ DTU Biosustain, Technical University of DenmarkVerifisert e-postadresse på biosustain.dtu.dk
Matthew M. DraelosDepartment of Chemistry, Duke UniversityVerifisert e-postadresse på duke.edu
Edward KalkreuterPostdoc, Scripps FloridaVerifisert e-postadresse på scripps.edu
Shan RandallNorth Carolina State UniversityVerifisert e-postadresse på ncsu.edu
Zhixia YePostdoctoral Associate, Duke UniversityVerifisert e-postadresse på duke.edu
Andrew N LowellVirginia TechVerifisert e-postadresse på vt.edu
David H. ShermanUniversity of MichiganVerifisert e-postadresse på umich.edu
Phyo Phyo Kyaw ZinCheminformatics PostdocVerifisert e-postadresse på simulations-plus.com
Anuran Kumar GayenGraduate Student, North Carolina State UniversityVerifisert e-postadresse på ncsu.edu
Juyuan YangPhD student, Georgia Institute of TechnologyVerifisert e-postadresse på gatech.edu
Douglas A. HansenSestina BioVerifisert e-postadresse på umich.edu
Joseph ChemlerZymergenVerifisert e-postadresse på zymergen.com
Shasha LiS. Scientist at Merck, Chemistry; PhD of Pharmacy, University of Michigan, Ann ArborVerifisert e-postadresse på umich.edu
T. Ashton CroppVirginia Commonwealth UniversityVerifisert e-postadresse på vcu.edu

Gavin Williams

Professor of Chemistry, NC State University

Verifisert e-postadresse på ncsu.edu - Startside

chemical biology synthetic biology natural product biosynthesis enzyme engineering chemo-enzymatic synthesis


Tittel Sortér etter sitater Sortér etter år Sortér etter tittel	Sitert av Sitert av	År
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution GJ Williams, C Zhang, JS Thorson Nature chemical biology 3 (10), 657-662, 2007	250	2007
Probing the aglycon promiscuity of an engineered glycosyltransferase RW Gantt, RD Goff, GJ Williams, JS Thorson Angewandte Chemie 120 (46), 9021-9024, 2008	138	2008
Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution GJ Williams, S Domann, A Nelson, A Berry Proceedings of the National Academy of Sciences 100 (6), 3143-3148, 2003	132	2003
Optimizing glycosyltransferase specificity via “hot spot” saturation mutagenesis presents a catalyst for novobiocin glycorandomization GJ Williams, RD Goff, C Zhang, JS Thorson Chemistry & biology 15 (4), 393-401, 2008	98	2008
Directed evolution of enzymes for biocatalysis and the life sciences GJ Williams, AS Nelson, A Berry Cellular and Molecular Life Sciences CMLS 61 (24), 3034-3046, 2004	97	2004
The impact of enzyme engineering upon natural product glycodiversification GJ Williams, RW Gantt, JS Thorson Current opinion in chemical biology 12 (5), 556-564, 2008	96	2008
Engineering polyketide synthases and nonribosomal peptide synthetases GJ Williams Current opinion in structural biology 23 (4), 603-612, 2013	81	2013
Creation of a pair of stereochemically complementary biocatalysts GJ Williams, T Woodhall, LM Farnsworth, A Nelson, A Berry Journal of the American Chemical Society 128 (50), 16238-16247, 2006	72	2006
Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases I Koryakina, J McArthur, S Randall, MM Draelos, EM Musiol, ... ACS chemical biology 8 (1), 200-208, 2013	71	2013
Recombinant E. coli Prototype Strains for in Vivo Glycorandomization GJ Williams, J Yang, C Zhang, JS Thorson ACS chemical biology 6 (1), 95-100, 2011	65	2011
Promiscuity of a modular polyketide synthase towards natural and non-natural extender units I Koryakina, JB McArthur, MM Draelos, GJ Williams Organic & biomolecular chemistry 11 (27), 4449-4458, 2013	56	2013
Natural product glycosyltransferases: properties and applications GJ Williams, JS Thorson Advances in Enzymology & Related Areas of Molecular Biology 76, 55, 2009	56	2009
Mutant malonyl‐CoA synthetases with altered specificity for polyketide synthase extender unit generation I Koryakina, GJ Williams ChemBioChem 12 (15), 2289-2293, 2011	55	2011
Creation of a tailored aldolase for the parallel synthesis of sialic acid mimetics T Woodhall, G Williams, A Berry, A Nelson Angewandte Chemie 117 (14), 2147-2150, 2005	50	2005
Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ... ACS chemical biology 12 (1), 114-123, 2017	45	2017
A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution GJ Williams, JS Thorson Nature protocols 3 (3), 357-362, 2008	44	2008
Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology CM Kasey, M Zerrad, Y Li, TA Cropp, GJ Williams ACS synthetic biology 7 (1), 227-239, 2018	41	2018
Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase Z Ye, EM Musiol, T Weber, GJ Williams Chemistry & biology 21 (5), 636-646, 2014	40	2014
Structure-guided saturation mutagenesis of N-acetylneuraminic acid lyase for the synthesis of sialic acid mimetics GJ Williams, T Woodhall, A Nelson, A Berry Protein Engineering Design and Selection 18 (5), 239-246, 2005	33	2005
Polyketide bioderivatization using the promiscuous acyltransferase KirCII EM Musiol-Kroll, F Zubeil, T Schafhauser, T Härtner, A Kulik, J McArthur, ... ACS synthetic biology 6 (3), 421-427, 2017	31	2017

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