| A surface on the androgen receptor that allosterically regulates coactivator binding E Estébanez-Perpiñá, LA Arnold, P Nguyen, ED Rodrigues, E Mar, ... Proceedings of the National Academy of Sciences 104 (41), 16074-16079, 2007 | 336 | 2007 |
| The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor E Estébanez-Perpiná, JMR Moore, E Mar, E Delgado-Rodrigues, ... Journal of Biological Chemistry 280 (9), 8060-8068, 2005 | 194 | 2005 |
| Structure of the homodimeric androgen receptor ligand-binding domain M Nadal, S Prekovic, N Gallastegui, C Helsen, M Abella, K Zielinska, ... Nature communications 8 (1), 14388, 2017 | 160 | 2017 |
| Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators LA Arnold, E Estébanez-Perpiñá, M Togashi, N Jouravel, A Shelat, ... Journal of Biological Chemistry 280 (52), 43048-43055, 2005 | 129 | 2005 |
| Nuclear receptor crosstalk — defining the mechanisms for therapeutic innovation K De Bosscher, SJ Desmet, D Clarisse, E Estébanez-Perpiña, ... Nature Reviews Endocrinology, 2020 | 124 | 2020 |
| EPI-001, a compound active against castration-resistant prostate cancer, targets transactivation unit 5 of the androgen receptor. SX De Mol E, Fenwick RB, Phang CT, Buzon V, Szulc E, De La Fuente A ... ACS Chem Biol, 2016 | 124* | 2016 |
| A conserved surface on the ligand binding domain of nuclear receptors for allosteric control V Buzón, LR Carbó, SB Estruch, RJ Fletterick, E Estébanez-Perpiñá Molecular and cellular endocrinology 348 (2), 394-402, 2012 | 89 | 2012 |
| Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue E Estébanez-Perpiñá, P Fuentes-Prior, D Belorgey, M Braun, ... Walter de Gruyter 381 (12), 1203-1214, 2000 | 84 | 2000 |
| Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor E Estebanez-Perpina, LA Arnold, N Jouravel, M Togashi, J Blethrow, ... Molecular Endocrinology 21 (12), 2919-2928, 2007 | 73 | 2007 |
| Advances in our structural understanding of orphan nuclear receptors N Gallastegui, JAG Mackinnon, RJ Fletterick, E Estébanez-Perpiñá Trends in biochemical sciences 40 (1), 25-35, 2015 | 67 | 2015 |
| Allosteric conversation in the androgen receptor ligand-binding domain surfaces S Grosdidier, LR Carbó, V Buzón, G Brooke, P Nguyen, JD Baxter, ... Molecular Endocrinology 26 (7), 1078-1090, 2012 | 67 | 2012 |
| The 2.2-Å crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features C Hink-Schauer, E Estébanez-Perpiná, E Wilharm, P Fuentes-Prior, ... Journal of Biological Chemistry 277 (52), 50923-50933, 2002 | 66 | 2002 |
| Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif K Jehle, L Cato, A Neeb, C Muhle-Goll, N Jung, EW Smith, V Buzon, ... Journal of Biological Chemistry 289 (13), 8839-8851, 2014 | 65 | 2014 |
| Crystal structure of the apoptosis-inducing human granzyme A dimer C Hink-Schauer, E Estébanez-Perpiñá, FC Kurschus, W Bode, DE Jenne Nature Structural & Molecular Biology 10 (7), 535-540, 2003 | 65 | 2003 |
| Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure− activity relationships LA Arnold, A Kosinski, E Estébanez-Perpiñá, RK Guy Journal of medicinal chemistry 50 (22), 5269-5280, 2007 | 52 | 2007 |
| Effects of adult dysthyroidism on the morphology of hippocampal neurons J Sala-Roca, E Estebanez-Perpina, F Balada, A Garau, ... Behavioural brain research 188 (2), 348-354, 2008 | 51 | 2008 |
| Regulation of androgen receptor activity by transient interactions of its transactivation domain with general transcription regulators E De Mol, E Szulc, C Di Sanza, P Martínez-Cristóbal, CW Bertoncini, ... Structure 26 (1), 145-152. e3, 2018 | 49 | 2018 |
| Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera E Estébanez-Perpiñá, A Bayés, J Vendrell, MA Jongsma, DP Bown, ... Journal of molecular biology 313 (3), 629-638, 2001 | 42 | 2001 |
| A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding LA Arnold, E Estébanez-Perpiñá, M Togashi, A Shelat, CA Ocasio, ... Science's STKE 2006 (341), pl3-pl3, 2006 | 36 | 2006 |
| Eighty Years of Targeting Androgen Receptor Activity in Prostate Cancer: The Fight Goes on E Estébanez-Perpiñá, C Bevan, I McEwan Cancers 13 (3), 509, 2021 | 34 | 2021 |
Robert FletterickUCSFVerifisert e-postadresse på UCSF.edu
