| Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: considerations for the validation of a quantitative … N Spooner, R Lad, M Barfield Analytical chemistry 81 (4), 1557-1563, 2009 | 496 | 2009 |
| Volumetric absorptive microsampling: a dried sample collection technique for quantitative bioanalysis P Denniff, N Spooner Analytical chemistry 86 (16), 8489-8495, 2014 | 382 | 2014 |
| The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs P Denniff, N Spooner Bioanalysis 2 (8), 1385-1395, 2010 | 332 | 2010 |
| Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies M Barfield, N Spooner, R Lad, S Parry, S Fowles Journal of Chromatography B 870 (1), 32-37, 2008 | 311 | 2008 |
| The effect of tributyltin upon steroid titres in the female dogwhelk, Nucella lapillus, and the development of imposex N Spooner, PE Gibbs, GW Bryan, LJ Goad Marine environmental research 32 (1-4), 37-49, 1991 | 291 | 1991 |
| Quantitative analysis of therapeutic drugs in dried blood spot samples by paper spray mass spectrometry: an avenue to therapeutic drug monitoring NE Manicke, P Abu-Rabie, N Spooner, Z Ouyang, RG Cooks Journal of the American Society for Mass Spectrometry 22 (9), 1501-1507, 2011 | 268 | 2011 |
| A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit N Spooner, P Denniff, L Michielsen, R De Vries, QC Ji, ME Arnold, ... Bioanalysis 7 (6), 653-659, 2015 | 222 | 2015 |
| Reduction of signal suppression effects in ESI-MS using a nanosplitting device ET Gangl, M Annan, N Spooner, P Vouros Analytical chemistry 73 (23), 5635-5644, 2001 | 221 | 2001 |
| The effect of hematocrit and punch location on assay bias during quantitative bioanalysis of dried blood spot samples M O’mara, B Hudson-Curtis, K Olson, Y Yueh, J Dunn, N Spooner Bioanalysis 3 (20), 2335-2347, 2011 | 186 | 2011 |
| Direct quantitative bioanalysis of drugs in dried blood spot samples using a thin-layer chromatography mass spectrometer interface P Abu-Rabie, N Spooner Analytical chemistry 81 (24), 10275-10284, 2009 | 142 | 2009 |
| Investigation of different approaches to incorporating internal standard in DBS quantitative bioanalytical workflows and their effect on nullifying hematocrit-based assay bias P Abu-Rabie, P Denniff, N Spooner, BZ Chowdhry, FS Pullen Analytical Chemistry 87 (9), 4996-5003, 2015 | 110 | 2015 |
| Method of applying internal standard to dried matrix spot samples for use in quantitative bioanalysis P Abu-Rabie, P Denniff, N Spooner, J Brynjolffssen, P Galluzzo, ... Analytical Chemistry 83 (22), 8779-8786, 2011 | 83 | 2011 |
| Quantitative bioanalysis of paracetamol in rats using volumetric absorptive microsampling (VAMS) P Denniff, S Parry, W Dopson, N Spooner Journal of pharmaceutical and biomedical analysis 108, 61-69, 2015 | 79 | 2015 |
| In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium Z Cobb, R de Vries, N Spooner, S Williams, L Staelens, M Doig, ... Bioanalysis 5 (17), 2161-2169, 2013 | 74 | 2013 |
| Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies K Chapman, S Chivers, D Gliddon, D Mitchell, S Robinson, T Sangster, ... Drug discovery today 19 (5), 528-532, 2014 | 72 | 2014 |
| Isolation and characterisation of intact steryl ferulates from seeds RP Evershed, N Spooner, MC Prescott, LJ Goad Journal of Chromatography A 440, 23-35, 1988 | 69 | 1988 |
| Direct ionization of solid-phase microextraction fibers for quantitative drug bioanalysis: from peripheral circulation to mass spectrometry detection S Ahmad, M Tucker, N Spooner, D Murnane, U Gerhard Analytical chemistry 87 (1), 754-759, 2015 | 68 | 2015 |
| Application of atmospheric pressure ionization time-of-flight mass spectrometry coupled with liquid chromatography for the characterization of in vitro drug metabolites H Zhang, J Henion, Y Yang, N Spooner Analytical chemistry 72 (14), 3342-3348, 2000 | 62 | 2000 |
| Microsampling: considerations for its use in pharmaceutical drug discovery and development N Spooner, KD Anderson, J Siple, ER Wickremsinhe, Y Xu, M Lee Bioanalysis 11 (10), 1015-1038, 2019 | 61 | 2019 |
| Dried blood spots, pharmacokinetic studies and better medicines for children HC Pandya, N Spooner, H Mulla Bioanalysis 3 (7), 779-786, 2011 | 61 | 2011 |
Hitesh PandyaExec. Medical Director AstraZeneca and Hon. Senior Lecturer Leicester UniversityVerifisert e-postadresse på leicester.ac.uk
