| Site-Specific Incorporation of a 19F-Amino Acid into Proteins as an NMR Probe for Characterizing Protein Structure and Reactivity JC Jackson, JT Hammill, RA Mehl Journal of the American Chemical Society 129 (5), 1160-1166, 2007 | 237 | 2007 |
| Preparation of site-specifically labeled fluorinated proteins for 19F-NMR structural characterization JT Hammill, S Miyake-Stoner, JL Hazen, JC Jackson, RA Mehl Nature protocols 2 (10), 2601-2607, 2007 | 200 | 2007 |
| Probing protein folding using site-specifically encoded unnatural amino acids as FRET donors with tryptophan SJ Miyake-Stoner, AM Miller, JT Hammill, JC Peeler, KR Hess, RA Mehl, ... Biochemistry 48 (25), 5953-5962, 2009 | 156 | 2009 |
| Generating permissive site-specific unnatural aminoacyl-tRNA synthetases SJ Miyake-Stoner, CA Refakis, JT Hammill, H Lusic, JL Hazen, A Deiters, ... Biochemistry 49 (8), 1667-1677, 2010 | 122 | 2010 |
| Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 92 | 2017 |
| Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria JL Keffer, S Huecas, JT Hammill, P Wipf, JM Andreu, CA Bewley Bioorganic & medicinal chemistry 21 (18), 5673-5678, 2013 | 59 | 2013 |
| Discovery of an orally bioavailable inhibitor of defective in cullin neddylation 1 (DCN1)-mediated cullin neddylation JT Hammill, D Bhasin, DC Scott, J Min, Y Chen, Y Lu, L Yang, HS Kim, ... Journal of medicinal chemistry 61 (7), 2694-2706, 2018 | 52 | 2018 |
| Piperidinyl ureas chemically control defective in cullin neddylation 1 (DCN1)-mediated cullin neddylation JT Hammill, DC Scott, J Min, MC Connelly, G Holbrook, F Zhu, A Matheny, ... Journal of medicinal chemistry 61 (7), 2680-2693, 2018 | 41 | 2018 |
| Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening D Ortiz, WA Guiguemde, JT Hammill, AK Carrillo, Y Chen, M Connelly, ... PLoS neglected tropical diseases 11 (12), e0006157, 2017 | 36 | 2017 |
| Discovery of novel pyrazolo-pyridone DCN1 inhibitors controlling cullin neddylation HS Kim, JT Hammill, DC Scott, Y Chen, J Min, J Rector, B Singh, ... Journal of medicinal chemistry 62 (18), 8429-8442, 2019 | 32 | 2019 |
| Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A JE Zuniga, JT Hammill, O Drory, JE Nuss, JC Burnett, R Gussio, P Wipf, ... PloS one 5 (6), e11378, 2010 | 32 | 2010 |
| Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments JL Keffer, JT Hammill, JR Lloyd, A Plaza, P Wipf, CA Bewley Marine drugs 10 (5), 1103-1125, 2012 | 24 | 2012 |
| Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines S Eagon, JT Hammill, M Sigal, KJ Ahn, JE Tryhorn, G Koch, B Belanger, ... Journal of Medicinal Chemistry 63 (20), 11902-11919, 2020 | 22 | 2020 |
| Synthesis and chemical diversity analysis of bicyclo [3.3. 1] non-3-en-2-ones JT Hammill, J Contreras-García, AM Virshup, DN Beratan, W Yang, P Wipf Tetrahedron 66 (31), 5852-5862, 2010 | 22 | 2010 |
| Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439) GRK Kim HS, Hammill JT J Med Chem. 60 (7), 2651-2653, 2017 | 19 | 2017 |
| Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein S Eagon, JT Hammill, J Bach, N Everson, TA Sisley, MJ Walls, S Durham, ... Bioorganic & medicinal chemistry letters 30 (21), 127502, 2020 | 15 | 2020 |
| Improvement of oral bioavailability of pyrazolo-pyridone inhibitors of the interaction of DCN1/2 and UBE2M HS Kim, JT Hammill, DC Scott, Y Chen, AL Rice, W Pistel, B Singh, ... Journal of medicinal chemistry 64 (9), 5850-5862, 2021 | 10 | 2021 |
| Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones Y Chen, F Zhu, J Hammill, G Holbrook, L Yang, B Freeman, KL White, ... Malaria Journal 20, 1-15, 2021 | 8 | 2021 |
| Amino-substituted 3-Aryl-and 3-heteroarylquinolines as potential antileishmanial agents JT Hammill, VM Sviripa, LM Kril, D Ortiz, CM Fargo, HS Kim, Y Chen, ... Journal of Medicinal Chemistry 64 (16), 12152-12162, 2021 | 6 | 2021 |
| Evaluation of 1, 1-cyclopropylidene as a thioether isostere in the 4-thio-thienopyrimidine (TTP) series of antimalarials RD Barrows, JT Hammill, MC Tran, MO Falade, AL Rice, CW Davis, ... Bioorganic & Medicinal Chemistry 28 (22), 115758, 2020 | 6 | 2020 |
