|Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore|
BE Young, SWX Ong, S Kalimuddin, JG Low, SY Tan, J Loh, OT Ng, ...
Jama 323 (15), 1488-1494, 2020
|Autoantibodies against type I IFNs in patients with life-threatening COVID-19|
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ...
Science 370 (6515), eabd4585, 2020
|Inborn errors of type I IFN immunity in patients with life-threatening COVID-19|
Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ...
Science 370 (6515), eabd4570, 2020
|Baricitinib plus remdesivir for hospitalized adults with Covid-19|
AC Kalil, TF Patterson, AK Mehta, KM Tomashek, CR Wolfe, V Ghazaryan, ...
New England Journal of Medicine 384 (9), 795-807, 2021
|A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction|
CW Tan, WN Chia, X Qin, P Liu, MIC Chen, C Tiu, Z Hu, VCW Chen, ...
Nature biotechnology 38 (9), 1073-1078, 2020
|Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients|
PY Chia, KK Coleman, YK Tan, SWX Ong, M Gum, SK Lau, XF Lim, ...
Nature communications 11 (1), 1-7, 2020
|Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures|
R Pung, CJ Chiew, BE Young, S Chin, MIC Chen, HE Clapham, AR Cook, ...
The Lancet 395 (10229), 1039-1046, 2020
|Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients|
AT Tan, M Linster, CW Tan, N Le Bert, WN Chia, K Kunasegaran, ...
Cell reports 34 (6), 2021
|Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a …|
PNA Harris, PA Tambyah, DC Lye, Y Mo, TH Lee, M Yilmaz, TH Alenazi, ...
Jama 320 (10), 984-994, 2018
|Assessing viral shedding and infectivity of tears in coronavirus disease 2019 (COVID-19) patients|
IYJ Seah, DE Anderson, AEZ Kang, L Wang, P Rao, BE Young, DC Lye, ...
Ophthalmology 127 (7), 977-979, 2020
|Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study|
BE Young, SW Fong, YH Chan, TM Mak, LW Ang, DE Anderson, CYP Lee, ...
The lancet 396 (10251), 603-611, 2020
|Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients|
CM Poh, G Carissimo, B Wang, SN Amrun, CYP Lee, RSL Chee, ...
Nature communications 11 (1), 2806, 2020
|Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study|
PY Chia, SWX Ong, CJ Chiew, LW Ang, JM Chavatte, TM Mak, L Cui, ...
Clinical microbiology and infection 28 (4), 612. e1-612. e7, 2022
|Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths|
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
|Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study|
WN Chia, F Zhu, SWX Ong, BE Young, SW Fong, N Le Bert, CW Tan, ...
The Lancet Microbe 2 (6), e240-e249, 2021
|Clinical and virological features of SARS-CoV-2 variants of concern: a retrospective cohort study comparing B. 1.1. 7 (Alpha), B. 1.315 (Beta), and B. 1.617. 2 (Delta)|
SWX Ong, CJ Chiew, LW Ang, TM Mak, L Cui, MPHS Toh, YD Lim, ...
|Risk factors for severe disease and efficacy of treatment in patients infected with COVID-19: a systematic review, meta-analysis, and meta-regression analysis|
JJY Zhang, KS Lee, LW Ang, YS Leo, BE Young
Clinical Infectious Diseases 71 (16), 2199-2206, 2020
|A neutralizing monoclonal antibody for hospitalized patients with Covid-19|
Activ-3/Tico Ly-CoV555 Study Group
New England Journal of Medicine 384 (10), 905-914, 2021
|X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19|
T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
Science immunology 6 (62), eabl4348, 2021
|Discovery and genomic characterization of a 382-nucleotide deletion in ORF7b and ORF8 during the early evolution of SARS-CoV-2|
YCF Su, DE Anderson, BE Young, M Linster, F Zhu, J Jayakumar, ...
MBio 11 (4), 10.1128/mbio. 01610-20, 2020