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Deniz B Temel
Deniz B Temel
Senior Research Investigator, Bristol-Myers Squibb
No verified email
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Cited by
Cited by
Year
The molecular mechanism of nuclear transport revealed by atomic-scale measurements
LE Hough, K Dutta, S Sparks, DB Temel, A Kamal, J Tetenbaum-Novatt, ...
Elife 4, e10027, 2015
1552015
Orthogonal methods for characterizing the unfolding of therapeutic monoclonal antibodies: differential scanning calorimetry, isothermal chemical denaturation, and intrinsic …
DB Temel, P Landsman, ML Brader
Methods in enzymology 567, 359-389, 2016
852016
Regulatory interactions between a bacterial tyrosine kinase and its cognate phosphatase
DB Temel, K Dutta, S Alphonse, J Nourikyan, C Grangeasse, R Ghose
Journal of Biological Chemistry 288 (21), 15212-15228, 2013
342013
Deciphering the “fuzzy” interaction of FG nucleoporins and transport factors using small-angle neutron scattering
S Sparks, DB Temel, MP Rout, D Cowburn
Structure 26 (3), 477-484. e4, 2018
202018
Utility of solution x-ray scattering for the development of antibody biopharmaceuticals
H Inouye, D Houde, DB Temel, L Makowski
Journal of Pharmaceutical Sciences 105 (11), 3278-3289, 2016
182016
Evaluation of incremental siliconization levels on soluble aggregates, submicron and subvisible particles in a prefilled syringe product
S Bai, P Landsman, A Spencer, D DeCollibus, F Vega, DB Temel, ...
Journal of Pharmaceutical Sciences 105 (1), 50-63, 2016
172016
Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D
A Natarajan, K Dutta, DB Temel, PA Nair, S Shuman, R Ghose
Nucleic acids research 40 (5), 2076-2088, 2012
82012
Developability in biophysical characterization
DB Temel, F Kinderman, E Eryilmaz
Biophysical characterization of proteins in developing biopharmaceuticals …, 2020
72020
Sequence-specific backbone 1H, 13C and 15N assignments of the catalytic domain of the Escherichia coli protein tyrosine kinase, Wzc
DB Temel, K Dutta, R Ghose
Biomolecular NMR assignments 8, 37-41, 2014
32014
Resolving liquid-liquid phase separation for a peptide fused monoclonal antibody by formulation optimization
W Qi, L Alekseychyk, N Nuanmanee, DB Temel, V Jann, M Treuheit, ...
Journal of Pharmaceutical Sciences 110 (2), 738-745, 2021
22021
Atomic Scale Dynamic Behavior of the Nuclear Transport Selectivity Barrier
L Hough, K Dutta, A Kamal, D Temel, S Sparks, J Tetenbaum-Novatt, ...
Molecular biology of the cell 25, 2014
12014
Engineering monoclonal antibodies to improve stability and production titer
JL Stevens, D Temel, B Estes, NJ Agrawal
US Patent App. 17/420,231, 2022
2022
Deciphering the'fuzzy'interaction of FG nucleoporins and transport factors using SANS
D Cowburn, S Sparks, DB Temel, MP Rout
Acta Crystallographica Section A: Foundations and Advances 75, a395-a395, 2019
2019
The Role of Intrinsic Disorder in the Molecular Mechanism of Nuclear Transport
LK Maguire, K Wall, G Armstrong, K Dutta, S Sparks, DB Temel, A Kamal, ...
Biophysical Journal 110 (3), 558a, 2016
2016
The Behavior of the Intrinsically Disordered FG Nups Determined by in Cell NMR
L Hough, K Dutta, A Kamal, D Temel, S Sparks, J Tetenbaum-Novatt, ...
Biophysical Journal 104 (2), 120a, 2013
2013
Interactions between a Bacterial Tyrosine Kinase and its Cognate Phosphatase--- A Solution NMR Study
DB Temel
Dissertation Abstracts International 73 (108), 2012, 2012
2012
Utility of X-ray scattering for the development of antibody biopharmaceuticals
H Inouye, D Houde, DB Temel, L Makowski
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