Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration JM Sonner, JF Antognini, RC Dutton, P Flood, AT Gray, RA Harris, ... Anesthesia & Analgesia 97 (3), 718-740, 2003 | 372 | 2003 |
Azo‐Propofols: Photochromic Potentiators of GABAA Receptors M Stein, SJ Middendorp, V Carta, E Pejo, DE Raines, SA Forman, E Sigel, ... Angewandte Chemie International Edition 51 (42), 10500-10504, 2012 | 170 | 2012 |
Methoxycarbonyl-etomidate: A Novel Rapidly Metabolized and Ultra–short-acting Etomidate Analogue that Does Not Produce Prolonged Adrenocortical Suppression JF Cotten, SS Husain, SA Forman, KW Miller, EW Kelly, HH Nguyen, ... The Journal of the American Society of Anesthesiologists 111 (2), 240-249, 2009 | 133 | 2009 |
Automated documentation error detection and notification improves anesthesia billing performance SF Spring, WS Sandberg, S Anupama, JL Walsh, WD Driscoll, DE Raines The Journal of the American Society of Anesthesiologists 106 (1), 157-163, 2007 | 125 | 2007 |
Is a new paradigm needed to explain how inhaled anesthetics produce immobility? EI Eger, DE Raines, SL Shafer, HC Hemmings Jr, JM Sonner Anesthesia & Analgesia 107 (3), 832-848, 2008 | 112 | 2008 |
Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics K Solt, EI Eger, DE Raines Anesthesia & Analgesia 102 (5), 1407-1411, 2006 | 108 | 2006 |
Carboetomidate: a pyrrole analog of etomidate designed not to suppress adrenocortical function JF Cotten, SA Forman, JK Laha, GD Cuny, SS Husain, KW Miller, ... The Journal of the American Society of Anesthesiologists 112 (3), 637-644, 2010 | 106 | 2010 |
Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels DE Raines, RJ Claycomb, M Scheller, SA Forman The Journal of the American Society of Anesthesiologists 95 (2), 470-477, 2001 | 72 | 2001 |
In vivo and in vitro pharmacological studies of methoxycarbonyl-carboetomidate E Pejo, JF Cotten, EW Kelly, R Le Ge, GD Cuny, JK Laha, J Liu, XJ Lin, ... Anesthesia & Analgesia 115 (2), 297-304, 2012 | 63 | 2012 |
Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols R Stevens, D Rüsch, K Solt, DE Raines, PA Davies Journal of Pharmacology and Experimental Therapeutics 314 (1), 338-345, 2005 | 59 | 2005 |
Aprotinin administration and pulmonary thromboembolism during orthotopic liver transplantation: report of two cases MG Fitzsimons, RA Peterfreund, DE Raines Anesthesia & Analgesia 92 (6), 1418-1421, 2001 | 58 | 2001 |
Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane Y Zhang, JM Sonner, EI Eger, CR Stabernack, MJ Laster, DE Raines, ... Anesthesia & Analgesia 99 (1), 85-90, 2004 | 56 | 2004 |
Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: interpretation within an allosteric kinetic model K Solt, D Ruesch, SA Forman, PA Davies, DE Raines Journal of Neuroscience 27 (48), 13151-13160, 2007 | 55 | 2007 |
Anesthetic drug development: Novel drugs and new approaches HV Chitilian, RG Eckenhoff, DE Raines Surgical Neurology International 4 (Suppl 1), S2, 2013 | 53 | 2013 |
Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand … SS Husain, S Nirthanan, D Ruesch, K Solt, Q Cheng, GD Li, E Arevalo, ... Journal of medicinal chemistry 49 (16), 4818-4825, 2006 | 52 | 2006 |
p-(4-Azipentyl)propofol: A Potent Photoreactive General Anesthetic Derivative of Propofol DS Stewart, PY Savechenkov, Z Dostalova, DC Chiara, R Ge, DE Raines, ... Journal of medicinal chemistry 54 (23), 8124-8135, 2011 | 51 | 2011 |
The N-methyl-d-aspartate receptor inhibitory potencies of aromatic inhaled drugs of abuse: evidence for modulation by cation-π interactions DE Raines, F Gioia, RJ Claycomb, RJ Stevens Journal of Pharmacology and Experimental Therapeutics 311 (1), 14-21, 2004 | 50 | 2004 |
Anesthetic cutoff in cycloalkanemethanols. A test of current theories. DE Raines, SE Korten, AG Hill, KW Miller Anesthesiology 78 (5), 918-927, 1993 | 49 | 1993 |
Allyl m-Trifluoromethyldiazirine Mephobarbital: An Unusually Potent Enantioselective and Photoreactive Barbiturate General Anesthetic PY Savechenkov, X Zhang, DC Chiara, DS Stewart, R Ge, X Zhou, ... Journal of medicinal chemistry 55 (14), 6554-6565, 2012 | 48 | 2012 |
General anesthetic-induced channel gating enhancement of 5-hydroxytryptamine type 3 receptors depends on receptor subunit composition K Solt, RJ Stevens, PA Davies, DE Raines Journal of Pharmacology and Experimental Therapeutics 315 (2), 771-776, 2005 | 48 | 2005 |