| A landscape of driver mutations in melanoma E Hodis, IR Watson, GV Kryukov, ST Arold, M Imielinski, JP Theurillat, ... Cell 150 (2), 251-263, 2012 | 2921 | 2012 |
| Genomic Classification of Cutaneous Melanoma TCGA Network Cell 161 (7), 1681-96, 2015 | 2656* | 2015 |
| Melanoma genome sequencing reveals frequent PREX2 mutations MF Berger, E Hodis, TP Heffernan, YL Deribe, MS Lawrence, ... Nature 485 (7399), 502-506, 2012 | 877 | 2012 |
| Emerging patterns of somatic mutations in cancer IR Watson, K Takahashi, PA Futreal, L Chin Nature Reviews Genetics 14 (10), 703-718, 2013 | 568 | 2013 |
| Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations M Dankner, AAN Rose, S Rajkumar, PM Siegel, IR Watson Oncogene 37 (24), 3183-3199, 2018 | 402 | 2018 |
| NEDD8 pathways in cancer, Sine Quibus Non IR Watson, MS Irwin, M Ohh Cancer cell 19 (2), 168-176, 2011 | 203 | 2011 |
| The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF IR Watson, L Li, PK Cabeceiras, M Mahdavi, T Gutschner, G Genovese, ... Cancer research 74 (17), 4845-4852, 2014 | 180 | 2014 |
| Immature low-density neutrophils exhibit metabolic flexibility that facilitates breast cancer liver metastasis BE Hsu, S Tabariès, RM Johnson, S Andrzejewski, J Senecal, C Lehuédé, ... Cell reports 27 (13), 3902-3915. e6, 2019 | 167 | 2019 |
| Why is melanoma so metastatic? RR Braeuer, IR Watson, CJ Wu, AK Mobley, T Kamiya, E Shoshan, ... Pigment cell & melanoma research 27 (1), 19-36, 2014 | 147 | 2014 |
| Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function IR Watson, A Blanch, DCC Lin, M Ohh, MS Irwin Journal of biological chemistry 281 (45), 34096-34103, 2006 | 140 | 2006 |
| Eukaryotic translation elongation factor 1-alpha 1 inhibits p53 and p73 dependent apoptosis and chemotherapy sensitivity A Blanch, F Robinson, IR Watson, LS Cheng, MS Irwin PLoS One 8 (6), e66436, 2013 | 129 | 2013 |
| Tumor-associated B-cells induce tumor heterogeneity and therapy resistance R Somasundaram, G Zhang, M Fukunaga-Kalabis, M Perego, C Krepler, ... Nature communications 8 (1), 607, 2017 | 128 | 2017 |
| Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity L Kazak, JF Rahbani, B Samborska, GZ Lu, MP Jedrychowski, M Lajoie, ... Nature metabolism 1 (3), 360-370, 2019 | 125 | 2019 |
| Suppression of hypoxia-inducible factor 2α restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells AM Roberts, IR Watson, AJ Evans, DA Foster, MS Irwin, M Ohh Cancer research 69 (23), 9056-9064, 2009 | 115 | 2009 |
| Ubiquitin and ubiquitin-like modifications of the p53 family IR Watson, MS Irwin Neoplasia 8 (8), 655-666, 2006 | 112 | 2006 |
| Single-cell spatial immune landscapes of primary and metastatic brain tumours E Karimi, MW Yu, SM Maritan, LJM Perus, M Rezanejad, M Sorin, ... Nature 614 (7948), 555-563, 2023 | 102 | 2023 |
| Chemotherapy induces NEDP1-mediated destabilization of MDM2 IR Watson, BK Li, O Roche, A Blanch, M Ohh, MS Irwin Oncogene 29 (2), 297-304, 2010 | 79 | 2010 |
| Neutrophil oxidative stress mediates obesity-associated vascular dysfunction and metastatic transmigration SAC McDowell, RBE Luo, A Arabzadeh, S Doré, NC Bennett, V Breton, ... Nature Cancer 2 (5), 545-562, 2021 | 74 | 2021 |
| Molecular characterisation of cutaneous melanoma: creating a framework for targeted and immune therapies S Rajkumar, IR Watson British journal of cancer 115 (2), 145-155, 2016 | 74 | 2016 |
| Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response IIL Hwang, IR Watson, SD Der, M Ohh Journal of virology 80 (21), 10712-10723, 2006 | 74 | 2006 |
