Albert A. de Graaf
Albert A. de Graaf
TNO Microbiology and Systems Biology, Netherlands
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13C metabolic flux analysis
W Wiechert
Metabolic engineering 3 (3), 195-206, 2001
Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol
GA Sprenger, U Schörken, T Wiegert, S Grolle, AA De Graaf, SV Taylor, ...
Proceedings of the National Academy of Sciences 94 (24), 12857-12862, 1997
Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing
A Marx, AA de Graaf, W Wiechert, L Eggeling, H Sahm
Biotechnology and bioengineering 49 (2), 111-129, 1996
A universal framework for 13C metabolic flux analysis
W Wiechert, M Möllney, S Petersen, AA de Graaf
Metabolic engineering 3 (3), 265-283, 2001
Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems
W Wiechert, M Möllney, N Isermann, M Wurzel, AA de Graaf
Biotechnology and bioengineering 66 (2), 69-85, 1999
Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments
W Wiechert, AA de Graaf
Biotechnology and bioengineering 55 (1), 101-117, 1997
Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses withCorynebacterium glutamicum during growth on acetate and/or …
VF Wendisch, AA de Graaf, H Sahm, BJ Eikmanns
Journal of Bacteriology 182 (11), 3088-3096, 2000
Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis
W Wiechert, C Siefke, AA de Graaf, A Marx
Biotechnology and bioengineering 55 (1), 118-135, 1997
Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments
M Möllney, W Wiechert, D Kownatzki, AA de Graaf
Biotechnology and bioengineering 66 (2), 86-103, 1999
Beyond diversity: functional microbiomics of the human colon
M Egert, AA De Graaf, H Smidt, WM De Vos, K Venema
Trends in microbiology 14 (2), 86-91, 2006
In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum
M Möllney, W Wiechert, S Petersen, L Eggeling, H Sahm, AA de Graaf
Journal of Biological Chemistry 275 (46), 35932-35941, 2000
Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria
S Textor, VF Wendisch, AA De Graaf, U Müller, MI Linder, D Linder, ...
Archives of microbiology 168 (5), 428-436, 1997
Pathway analysis and metabolic engineering in Corynebacterium glutamicum
H Sahm, L Eggeling, AA de Graaf
Biological chemistry 381 (9-10), 899-910, 2000
Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum Quantification by 13C‐ and 1H‐NMR spectroscopy
European journal of biochemistry 213 (3), 1325-1331, 1993
Kinetic properties of the glucose‐6‐phosphate and 6 phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose …
B Moritz, K Striegel, AA de Graaf, H Sahm
European Journal of Biochemistry 267 (12), 3442-3452, 2000
Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA‐based stable isotope probing
P Kovatcheva‐Datchary, M Egert, A Maathuis, M Rajilić‐Stojanović, ...
Environmental microbiology 11 (4), 914-926, 2009
Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by 13C labeling and NMR spectroscopy
S Flores, G Gosset, N Flores, AA De Graaf, F Bolı́var
Metabolic engineering 4 (2), 124-137, 2002
QUALITY: quantification improvement by converting lineshapes to the Lorentzian type
AA De Graaf, JE Van Dijk, W BoéE
Magnetic resonance in medicine 13 (3), 343-357, 1990
Improved quantification of in vivo1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting
AA De Graaf, W Bovee
Magnetic Resonance in Medicine 15 (2), 305-319, 1990
Response of the central metabolism inCorynebacterium glutamicumto the use of an NADH-dependent glutamate dehydrogenase
A Marx, BJ Eikmanns, H Sahm, AA de Graaf, L Eggeling
Metabolic engineering 1 (1), 35-48, 1999
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