| Toward the semiquantitative estimation of binding constants. Guides for peptide-peptide binding in aqueous solution DH Williams, JPL Cox, AJ Doig, M Gardner, U Gerhard, PT Kaye, AR Lal, ... Journal of the American Chemical Society 113 (18), 7020-7030, 1991 | 268 | 1991 |
| Glycopeptide antibiotic activity and the possible role of dimerization: a model for biological signaling JP Mackay, U Gerhard, DA Beauregard, DH Williams, MS Westwell, ... Journal of the American Chemical Society 116 (11), 4581-4590, 1994 | 258 | 1994 |
| Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. DH Williams, MS Searle, JP Mackay, U Gerhard, RA Maplestone Proceedings of the National Academy of Sciences 90 (4), 1172-1178, 1993 | 233 | 1993 |
| Partitioning of free energy contributions in the estimation of binding constants: residual motions and consequences for amide-amide hydrogen bond strengths MS Searle, DH Williams, U Gerhard Journal of the American Chemical Society 114 (27), 10697-10704, 1992 | 228 | 1992 |
| The role of the sugar and chlorine substituents in the dimerization of vancomycin antibiotics U Gerhard, JP Mackay, RA Maplestone, DH Williams Journal of the American Chemical Society 115 (1), 232-237, 1993 | 226 | 1993 |
| Dissection of the contributions toward dimerization of glycopeptide antibiotics JP Mackay, U Gerhard, DA Beauregard, RA Maplestone, DH Williams Journal of the American Chemical Society 116 (11), 4573-4580, 1994 | 186 | 1994 |
| Aryl sulfones: a new class of γ-secretase inhibitors M Teall, P Oakley, T Harrison, D Shaw, E Kay, J Elliott, U Gerhard, ... Bioorganic & medicinal chemistry letters 15 (10), 2685-2688, 2005 | 101 | 2005 |
| Metabolite identification in drug discovery. AP Watt, RJ Mortishire-Smith, U Gerhard, SR Thomas Current opinion in drug discovery & development 6 (1), 57-65, 2003 | 94 | 2003 |
| Direct ionization of solid-phase microextraction fibers for quantitative drug bioanalysis: from peripheral circulation to mass spectrometry detection S Ahmad, M Tucker, N Spooner, D Murnane, U Gerhard Analytical chemistry 87 (1), 754-759, 2015 | 68 | 2015 |
| Two conformers of the glycopeptide antibiotic teicoplanin with distinct ligand binding sites MS Westwell, U Gerhard, DH Williams The Journal of Antibiotics 48 (11), 1292-1298, 1995 | 50 | 1995 |
| The free energy change of restricting a bond rotation in the binding of peptide analogues to vancomycin group antibiotics U Gerhard, MS Searle, DH Williams Bioorganic & Medicinal Chemistry Letters 3 (5), 803-808, 1993 | 44 | 1993 |
| Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring KR Gibson, L Hitzel, RJ Mortishire-Smith, U Gerhard, RA Jelley, AJ Reeve, ... The Journal of Organic Chemistry 67 (26), 9354-9360, 2002 | 43 | 2002 |
| Rational design and binding of modified cell-wall peptides to vancomycin-group antibiotics: Factorising free energy contributions to binding SE Holroyd, P Groves, MS Searle, U Gerhard, DH Williams Tetrahedron 49 (41), 9171-9182, 1993 | 43 | 1993 |
| Neighboring group participation of the indole nucleus: An unusual DAST-mediated rearrangement reaction DJ Hallett, U Gerhard, SC Goodacre, L Hitzel, TJ Sparey, S Thomas, ... The Journal of Organic Chemistry 65 (16), 4984-4993, 2000 | 38 | 2000 |
| Ligands which bind weakly to vancomycin: studies by 13C NMR spectroscopy CM Pearce, U Gerhard, DH Williams Journal of the Chemical Society, Perkin Transactions 2, 159-162, 1995 | 37 | 1995 |
| Accelerated metabolite identification by “Extraction-NMR” U Gerhard, S Thomas, R Mortishire-Smith Journal of pharmaceutical and biomedical analysis 32 (3), 531-538, 2003 | 28 | 2003 |
| A new pyridazine series of GABAA α5 ligands MB van Niel, K Wilson, CH Adkins, JR Atack, JL Castro, DE Clarke, ... Journal of medicinal chemistry 48 (19), 6004-6011, 2005 | 27 | 2005 |
| Towards a semi-quantitative description of a bimolecular association involving weak interactions in aqueous solution DH Williams, MP Searle, MS Westwell, U Gerhard, SE Holroyd Philosophical Transactions of the Royal Society of London. Series A …, 1993 | 25 | 1993 |
| Aromatic compounds from the liverwort Plagiochila spinulosa JD Connolly, DS Rycroft, DL Srivastava, WJ Cole, P Ifeadike, SF Kimbu, ... Phytochemistry 50 (7), 1159-1165, 1999 | 23 | 1999 |
| NK1 antagonists based on seven membered lactam scaffolds JM Elliott, EJ Carlson, GG Chicchi, O Dirat, M Dominguez, U Gerhard, ... Bioorganic & medicinal chemistry letters 16 (11), 2929-2932, 2006 | 20 | 2006 |
Neil SpoonerFounder and Director, Spooner Bioanalytical SolutionsVerifisert e-postadresse på spoonerbioanalytical.co.uk
