| The target landscape of clinical kinase drugs S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ... Science 358 (6367), eaan4368, 2017 | 736 | 2017 |
| Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia KH Metzeler, T Herold, M Rothenberg-Thurley, S Amler, MC Sauerland, ... Blood, The Journal of the American Society of Hematology 128 (5), 686-698, 2016 | 570 | 2016 |
| Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations M Neumann, S Heesch, C Schlee, S Schwartz, N Gökbuget, D Hoelzer, ... Blood, The Journal of the American Society of Hematology 121 (23), 4749-4752, 2013 | 309 | 2013 |
| Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, ... Leukemia 33 (1), 64-74, 2019 | 256 | 2019 |
| Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia T Herold, M Rothenberg-Thurley, VV Grunwald, H Janke, D Goerlich, ... Leukemia 34 (12), 3161-3172, 2020 | 190 | 2020 |
| GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia PA Greif, A Dufour, NP Konstandin, B Ksienzyk, E Zellmeier, B Tizazu, ... Blood, The Journal of the American Society of Hematology 120 (2), 395-403, 2012 | 180 | 2012 |
| Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis T Herold, S Schneider, KH Metzeler, M Neumann, L Hartmann, ... haematologica 102 (1), 130, 2017 | 171 | 2017 |
| CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes C Reindl, H Quentmeier, K Petropoulos, PA Greif, T Benthaus, ... Clinical Cancer Research 15 (7), 2238-2247, 2009 | 137 | 2009 |
| Mutational spectrum of adult T-ALL M Neumann, S Vosberg, C Schlee, S Heesch, S Schwartz, N Gökbuget, ... Oncotarget 6 (5), 2754, 2015 | 123 | 2015 |
| Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing PA Greif, SH Eck, NP Konstandin, A Benet-Pages, B Ksienzyk, A Dufour, ... Leukemia 25 (5), 821-827, 2011 | 121 | 2011 |
| RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes PA Greif, NP Konstandin, KH Metzeler, T Herold, Z Pasalic, B Ksienzyk, ... Haematologica 97 (12), 1909, 2012 | 119 | 2012 |
| Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients EK Von der Heide, M Neumann, S Vosberg, AR James, MP Schroeder, ... Leukemia 31 (5), 1069-1078, 2017 | 117 | 2017 |
| Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis T Herold, KH Metzeler, S Vosberg, L Hartmann, C Röllig, F Stölzel, ... Blood, The Journal of the American Society of Hematology 124 (8), 1304-1311, 2014 | 111 | 2014 |
| In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components C Woischke, CW Schaaf, HM Yang, M Vieth, L Veits, H Geddert, B Märkl, ... Modern Pathology 30 (1), 95-103, 2017 | 107 | 2017 |
| A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia T Herold, V Jurinovic, AMN Batcha, SA Bamopoulos, ... haematologica 103 (3), 456, 2018 | 102 | 2018 |
| Clonal evolution of acute myeloid leukemia from diagnosis to relapse S Vosberg, PA Greif Genes, chromosomes and cancer 58 (12), 839-849, 2019 | 95 | 2019 |
| Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: an exome sequencing study of 50 patients PA Greif, L Hartmann, S Vosberg, SM Stief, R Mattes, I Hellmann, ... Clinical cancer research 24 (7), 1716-1726, 2018 | 83 | 2018 |
| Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia K Reiter, H Polzer, C Krupka, A Maiser, B Vick, M Rothenberg-Thurley, ... Leukemia 32 (2), 313-322, 2018 | 78 | 2018 |
| Loss of KDM6A confers drug resistance in acute myeloid leukemia SM Stief, AL Hanneforth, S Weser, R Mattes, M Carlet, WH Liu, ... Leukemia 34 (1), 50-62, 2020 | 74 | 2020 |
| Epigenetic events, remodelling enzymes and their relationship to chromatin organization in prostatic intraepithelial neoplasia and prostatic adenocarcinoma MA Mohamed, PA Greif, J Diamond, O Sharaf, P Maxwell, R Montironi, ... BJU international 99 (4), 908-915, 2007 | 70 | 2007 |
