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VALENTINA PIROTA
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Year
More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand
M Zuffo, A Guédin, ED Leriche, F Doria, V Pirota, V Gabelica, JL Mergny, ...
Nucleic Acids Research 46 (19), e115-e115, 2018
752018
Naphthalene diimides as multimodal G-quadruplex-selective ligands
V Pirota, M Nadai, F Doria, SN Richter
Molecules 24 (3), 426, 2019
662019
Reactivity of copper–α-synuclein peptide complexes relevant to Parkinson’s disease
S Dell’Acqua, V Pirota, C Anzani, MM Rocco, S Nicolis, D Valensin, ...
Metallomics 7 (7), 1091-1102, 2015
532015
Multimeric G-quadruplexes: A review on their biological roles and targeting
I Frasson, V Pirota, SN Richter, F Doria
International Journal of Biological Macromolecules 204, 89-102, 2022
512022
A catalytic and selective scissoring molecular tool for quadruplex nucleic acids
M Nadai, F Doria, M Scalabrin, V Pirota, V Grande, G Bergamaschi, ...
Journal of the American Chemical Society 140 (44), 14528-14532, 2018
412018
Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model
M Tassinari, M Zuffo, M Nadai, V Pirota, AC Sevilla Montalvo, F Doria, ...
Nucleic Acids Research 48 (9), 4627-4642, 2020
372020
Groundbreaking anticancer activity of highly diversified oxadiazole scaffolds
A Benassi, F Doria, V Pirota
International journal of molecular sciences 21 (22), 8692, 2020
332020
Manipulating color emission in 2D hybrid perovskites by fine tuning halide segregation: a transparent green emitter
A Zanetta, Z Andaji‐Garmaroudi, V Pirota, G Pica, FU Kosasih, L Gouda, ...
Advanced Materials 34 (1), 2105942, 2022
302022
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model
V Pirota, C Platella, D Musumeci, A Benassi, J Amato, B Pagano, ...
International Journal of Biological Macromolecules 166, 1320-1334, 2021
302021
The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
S Lago, M Nadai, E Ruggiero, M Tassinari, M Marušič, B Tosoni, I Frasson, ...
Nucleic acids research 49 (2), 847-863, 2021
272021
Copper (I) forms a redox-stable 1: 2 complex with α-synuclein N-terminal peptide in a membrane-like environment
S Dell’Acqua, V Pirota, E Monzani, F Camponeschi, R De Ricco, ...
Inorganic Chemistry 55 (12), 6100-6106, 2016
242016
Trifunctionalized naphthalene diimides and dimeric analogues as G-quadruplex-targeting anticancer agents selected by affinity chromatography
C Platella, V Pirota, D Musumeci, F Rizzi, S Iachettini, P Zizza, A Biroccio, ...
International Journal of Molecular Sciences 21 (6), 1964, 2020
222020
Copper‐Aβ Peptides and Oxidation of Catecholic Substrates: Reactivity and Endogenous Peptide Damage
V Pirota, S Dell'Acqua, E Monzani, S Nicolis, L Casella
Chemistry–A European Journal 22 (47), 16964-16973, 2016
222016
G-Quadruplex DNA as a target in pathogenic bacteria: efficacy of an extended naphthalene diimide ligand and its mode of action
R Cebrian, E Belmonte-Reche, V Pirota, A de Jong, JC Morales, ...
Journal of Medicinal Chemistry 65 (6), 4752-4766, 2021
192021
Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis
N Dominik, S Magri, R Currò, E Abati, S Facchini, M Corbetta, ...
Brain 146 (12), 5060-5069, 2023
182023
Design of disruptors of the Hsp90–Cdc37 Interface
I D’Annessa, N Hurwitz, V Pirota, GL Beretta, S Tinelli, M Woodford, ...
Molecules 25 (2), 360, 2020
182020
Oxadiazole/pyridine-based ligands: A structural tuning for enhancing G-quadruplex binding
F Doria, V Pirota, M Petenzi, MP Teulade-Fichou, D Verga, M Freccero
Molecules 23 (9), 2162, 2018
182018
An overview of quadruplex ligands: Their common features and chemotype diversity
V Pirota, M Stasi, A Benassi, F Doria
Annual Reports in Medicinal Chemistry 54, 163-196, 2020
172020
A fragment-based approach for the development of G-quadruplex ligands: role of the amidoxime moiety
M Tassinari, A Lena, E Butovskaya, V Pirota, M Nadai, M Freccero, ...
Molecules 23 (8), 1874, 2018
172018
Dyads of G‐Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration
F Doria, E Salvati, L Pompili, V Pirota, C D'Angelo, F Manoli, M Nadai, ...
Chemistry–A European Journal 25 (47), 11085-11097, 2019
152019
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