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Isaac Chiu
Isaac Chiu
Associate Professor, Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Bacteria activate sensory neurons that modulate pain and inflammation
IM Chiu, BA Heesters, N Ghasemlou, CA Von Hehn, F Zhao, J Tran, ...
Nature 501 (7465), 52-57, 2013
6382013
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
IM Chiu, ETA Morimoto, H Goodarzi, JT Liao, S O’Keeffe, HP Phatnani, ...
Cell reports 4 (2), 385-401, 2013
5572013
Nociceptor sensory neuron–immune interactions in pain and inflammation
FA Pinho-Ribeiro, WA Verri Jr, IM Chiu
Trends in immunology 38 (1), 5-19, 2017
5552017
Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology
IM Chiu, CA Von Hehn, CJ Woolf
Nature neuroscience 15 (8), 1063-1067, 2012
5312012
The human natural killer cell immune synapse
DM Davis, I Chiu, M Fassett, GB Cohen, O Mandelboim, JL Strominger
Proceedings of the National Academy of Sciences 96 (26), 15062-15067, 1999
4801999
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation
A Wallrapp, SJ Riesenfeld, PR Burkett, REE Abdulnour, J Nyman, ...
Nature 549 (7672), 351-356, 2017
4382017
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
IM Chiu, A Chen, Y Zheng, B Kosaras, SA Tsiftsoglou, TK Vartanian, ...
Proceedings of the National Academy of Sciences 105 (46), 17913-17918, 2008
3602008
Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis
Y Ma, J Li, I Chiu, Y Wang, JA Sloane, J Lü, B Kosaras, RL Sidman, ...
The Journal of cell biology 175 (2), 209-215, 2006
2822006
Silencing nociceptor neurons reduces allergic airway inflammation
S Talbot, REE Abdulnour, PR Burkett, S Lee, SJF Cronin, MA Pascal, ...
Neuron 87 (2), 341-354, 2015
2662015
Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury
M Zhang, WG Austen Jr, I Chiu, EM Alicot, R Hung, M Ma, N Verna, M Xu, ...
Proceedings of the National Academy of Sciences 101 (11), 3886-3891, 2004
2582004
Identification of the target self-antigens in reperfusion injury
M Zhang, EM Alicot, I Chiu, J Li, N Verna, T Vorup-Jensen, B Kessler, ...
The Journal of experimental medicine 203 (1), 141-152, 2006
2502006
Blocking neuronal signaling to immune cells treats streptococcal invasive infection
FA Pinho-Ribeiro, B Baddal, R Haarsma, M O’Seaghdha, NJ Yang, ...
Cell 173 (5), 1083-1097. e22, 2018
2222018
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia
P Baral, BD Umans, L Li, A Wallrapp, M Bist, T Kirschbaum, Y Wei, Y Zhou, ...
Nature medicine 24 (4), 417-426, 2018
2182018
Pain and immunity: implications for host defence
P Baral, S Udit, IM Chiu
Nature Reviews Immunology 19 (7), 433-447, 2019
1972019
Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity
IM Chiu, LB Barrett, EK Williams, DE Strochlic, S Lee, AD Weyer, S Lou, ...
Elife 3, 2014
1972014
Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice
IM Chiu, H Phatnani, M Kuligowski, JC Tapia, MA Carrasco, M Zhang, ...
Proceedings of the National Academy of Sciences 106 (49), 20960-20965, 2009
1822009
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts
BJ Wainger, ED Buttermore, JT Oliveira, C Mellin, S Lee, WA Saber, ...
Nature neuroscience 18 (1), 17-24, 2015
1812015
An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk
N Yissachar, Y Zhou, L Ung, NY Lai, JF Mohan, A Ehrlicher, DA Weitz, ...
Cell 168 (6), 1135-1148. e12, 2017
1762017
Targeted delivery of siRNA to macrophages for anti-inflammatory treatment
SS Kim, C Ye, P Kumar, I Chiu, S Subramanya, H Wu, P Shankar, ...
Molecular therapy 18 (5), 993-1001, 2010
1742010
Gut-innervating nociceptor neurons regulate Peyer’s patch microfold cells and SFB levels to mediate Salmonella host defense
NY Lai, MA Musser, FA Pinho-Ribeiro, P Baral, A Jacobson, P Ma, ...
Cell 180 (1), 33-49. e22, 2020
1492020
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