Yoku Hayakawa

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Kazuhiko KoikeThe University of Tokyo, Professor EmeritusVerifisert e-postadresse på umin.ac.jp
C. Benedikt WestphalenMedical Lead Precision OncologyVerifisert e-postadresse på med.lmu.de
Hayato NakagawaMie University Graduate School of Medicine, Department of Gastroenterology and HepatologyVerifisert e-postadresse på med.mie-u.ac.jp
Timothy C. WangColumbia UniversityVerifisert e-postadresse på columbia.edu
Samuel AsfahaUniversity of Western OntarioVerifisert e-postadresse på uwo.ca
Daniel WorthleyColonoscopy ClinicVerifisert e-postadresse på colonoscopyclinic.com.au
Priv.-Doz. Dr. med. Bernhard W. RenzKlinikum der Universität MünchenVerifisert e-postadresse på med.uni-muenchen.de
Yagnesh TailorColumbia University Medical CenterVerifisert e-postadresse på columbia.edu
Mitsuhiro FujishiroProfessor, Department of Gastroenterology and Clinical Oncology, The University of TokyoVerifisert e-postadresse på h.u-tokyo.ac.jp
Michael QuanteUniversity of FreiburgVerifisert e-postadresse på uniklinik-freiburg.de
Duan ChenProfessor of Medicine, Norwegian University of Science and TechnologyVerifisert e-postadresse på ntnu.no
keisuke tateishiThe University of Tokyo, Department of GastroenterologyVerifisert e-postadresse på umin.ac.jp
Helen RemottiColumbia UniversityVerifisert e-postadresse på columbia.edu
Zhengyu JiangColumbia University Medical centerVerifisert e-postadresse på cumc.columbia.edu
Karan NagarMemorial Sloan Kettering Cancer CenterVerifisert e-postadresse på mskcc.org
Wataru ShibataYokohama City UniversityVerifisert e-postadresse på umin.ac.jp
Satoki ShichijoOsaka International Cancer InstituteVerifisert e-postadresse på oici.jp
Henrik NienhüserWissenschaftlicher MitarbeiterVerifisert e-postadresse på med.uni-heidelberg.de
Antonia R SepulvedaProfessor, George Washigton UniversityVerifisert e-postadresse på mfa.gwu.edu
Adam BassNovartis Institutes of Biomedical ResearchVerifisert e-postadresse på novartis.com

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Yoku Hayakawa

The University of Tokyo

Verifisert e-postadresse på umin.ac.jp

Gastroenterology Stem cell Cancer Tumor microenvironment


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Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ... Cell 160 (1), 269-284, 2015	632	2015
Denervation suppresses gastric tumorigenesis CM Zhao, Y Hayakawa, Y Kodama, S Muthupalani, CB Westphalen, ... Science translational medicine 6 (250), 250ra115-250ra115, 2014	540	2014
Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling Y Hayakawa, K Sakitani, M Konishi, S Asfaha, R Niikura, H Tomita, ... Cancer cell 31 (1), 21-34, 2017	404	2017
Long-lived intestinal tuft cells serve as colon cancer–initiating cells CB Westphalen, S Asfaha, Y Hayakawa, Y Takemoto, DJ Lukin, AH Nuber, ... The Journal of clinical investigation 124 (3), 1283-1295, 2014	397	2014
β2 adrenergic-neurotrophin feedforward loop promotes pancreatic cancer BW Renz, R Takahashi, T Tanaka, M Macchini, Y Hayakawa, Z Dantes, ... Cancer cell 33 (1), 75-90. e7, 2018	373	2018
Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth K Sakamoto, S Maeda, Y Hikiba, H Nakagawa, Y Hayakawa, W Shibata, ... Clinical Cancer Research 15 (7), 2248-2258, 2009	299	2009
Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche Y Hayakawa, H Ariyama, J Stancikova, K Sakitani, S Asfaha, BW Renz, ... Cancer cell 28 (6), 800-814, 2015	285	2015
Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury S Saha, E Aranda, Y Hayakawa, P Bhanja, S Atay, NP Brodin, J Li, ... Nature communications 7 (1), 13096, 2016	248	2016
Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis CB Westphalen, Y Takemoto, T Tanaka, M Macchini, Z Jiang, BW Renz, ... Cell stem cell 18 (4), 441-455, 2016	221	2016
Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication S Shichijo, Y Hirata, R Niikura, Y Hayakawa, A Yamada, T Ushiku, ... Gastrointestinal endoscopy 84 (4), 618-624, 2016	212	2016
Krt19+/Lgr5− cells are radioresistant cancer-initiating stem cells in the colon and intestine S Asfaha, Y Hayakawa, A Muley, S Stokes, TA Graham, RE Ericksen, ... Cell stem cell 16 (6), 627-638, 2015	208	2015
Serum IL‐6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences H Nakagawa, S Maeda, H Yoshida, R Tateishi, R Masuzaki, T Ohki, ... International journal of cancer 125 (10), 2264-2269, 2009	200	2009
Cholinergic signaling via muscarinic receptors directly and indirectly suppresses pancreatic tumorigenesis and cancer stemness BW Renz, T Tanaka, M Sunagawa, R Takahashi, Z Jiang, M Macchini, ... Cancer discovery 8 (11), 1458-1473, 2018	196	2018
Tumor microenvironment in gastric cancers Y Oya, Y Hayakawa, K Koike Cancer science 111 (8), 2696-2707, 2020	190	2020
Oesophageal adenocarcinoma and gastric cancer: should we mind the gap? Y Hayakawa, N Sethi, AR Sepulveda, AJ Bass, TC Wang Nature Reviews Cancer 16 (5), 305-318, 2016	137	2016
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis H Nakagawa, Y Hikiba, Y Hirata, J Font-Burgada, K Sakamoto, ... Proceedings of the National Academy of Sciences 111 (3), 1090-1095, 2014	132	2014
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer Y Hayakawa, Y Hirata, H Nakagawa, K Sakamoto, Y Hikiba, H Kinoshita, ... Proceedings of the National Academy of Sciences 108 (2), 780-785, 2011	127	2011
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis E Del Poggetto, IL Ho, C Balestrieri, EY Yen, S Zhang, F Citron, R Shah, ... Science 373 (6561), eabj0486, 2021	119	2021
CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis Y Hayakawa, G Jin, H Wang, X Chen, CB Westphalen, S Asfaha, ... Gut 64 (4), 544-553, 2015	113	2015
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis TRM Lannagan, YK Lee, T Wang, J Roper, ML Bettington, L Fennell, ... Gut 68 (4), 684-692, 2019	105	2019

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