Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient … RJ Allaway, DA Fischer, FB de Abreu, TB Gardner, SR Gordon, RJ Barth, ... Oncotarget 7 (13), 17087-17102, 2016 | 49 | 2016 |
A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma GP Way, RJ Allaway, SJ Bouley, CE Fadul, Y Sanchez, CS Greene BMC genomics 18, 1-11, 2017 | 34 | 2017 |
Combined inhibition of both p110α and p110β isoforms of phosphatidylinositol 3-kinase is required for sustained therapeutic effect in PTEN-deficient, ER+ breast cancer SR Hosford, LM Dillon, SJ Bouley, R Rosati, W Yang, VS Chen, ... Clinical Cancer Research 23 (11), 2795-2805, 2017 | 31 | 2017 |
Host cell autophagy promotes BK virus infection SJ Bouley, MS Maginnis, A Derdowski, GV Gee, CD Nelson, AM Bara, ... Virology 456, 87-95, 2014 | 20 | 2014 |
Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells RJ Allaway, MD Wood, SL Downey, SJ Bouley, NA Traphagen, JD Wells, ... Oncotarget 9 (22), 15860, 2018 | 7 | 2018 |
PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing S Rajasekaran, E Khan, SR Ching, M Khan, JK Siddiqui, DF Gradia, C Lin, ... Nucleic acids research 50 (12), 7048-7066, 2022 | 6 | 2022 |
Composition and method for inhibiting borc complex to treat cancers with nf1 deficiency and dysregulated ras signaling Y Sanchez, SJ Bouley US Patent App. 17/641,877, 2022 | | 2022 |
Correcting Pathogenic Germline Mutations in Neurofibromatosis Type 1 (NF1) Using Novel Gene Therapies SJ Bouley, F Fernandez, EJM Scullion, BP Kleinstiver, JA Walker MOLECULAR THERAPY 30 (4), 489-489, 2022 | | 2022 |
Inhibition of autophagy as a novel therapy for the treatment of neurofibromatosis type 1 tumors M Stevens, Y Wang, S Bouley, T Mandigo, A Sharma, S Sengupta, ... | | 2021 |
Synthetic lethal screening identifies existing drugs with selective viability effects on Neurofibromatosis type-1 model systems Y Wang, M Stevens, TR Mandigo, SJ Bouley, A Sharma, S Sengupta, ... bioRxiv, 2021.12. 20.473481, 2021 | | 2021 |
Vinylogous thioester compounds and methods of use Y Sanchez, R Allaway, S Bouley, M Wood US Patent 9,873,705, 2018 | | 2018 |
PTEN status dictates the roles of PI3K isoforms p110 alpha and p110 beta in modulation of AKT/mTOR and response to growth factor signaling in ER plus breast cancer LM Dillon, SJ Bouley, TW Miller CANCER RESEARCH 75 (9), 2015 | | 2015 |
Abstract P5-20-02: PTEN status dictates the roles of PI3K isoforms p110α and p110β in modulation of AKT/mTOR and response to growth factor signaling in ER+ breast cancer LM Dillon, SJ Bouley, TW Miller Cancer Research 75 (9_Supplement), P5-20-02-P5-20-02, 2015 | | 2015 |
The p110β isoform of PI3K modulates response to growth factor receptor signaling in breast cancer cells irrespective of PTEN status SJ Bouley, LM Dillon, TW Miller Cancer Research 74 (19_Supplement), 3342-3342, 2014 | | 2014 |