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Sylvia Varland
Sylvia Varland
Senior Scientist, smartbax GmbH
Verified email at smartbax.de
Title
Cited by
Cited by
Year
Spotlight on protein N-terminal acetylation
R Ree, S Varland, T Arnesen
Experimental & molecular medicine 50 (7), 1-13, 2018
2852018
N‐terminal modifications of cellular proteins: the enzymes involved, their substrate specificities and biological effects
S Varland, C Osberg, T Arnesen
Proteomics 15 (14), 2385-2401, 2015
2062015
NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility
A Drazic, H Aksnes, M Marie, M Boczkowska, S Varland, E Timmerman, ...
Proceedings of the National Academy of Sciences 115 (17), 4399-4404, 2018
1722018
Actin post-translational modifications: the cinderella of cytoskeletal control
S Varland, J Vandekerckhove, A Drazic
Trends in biochemical sciences 44 (6), 502-516, 2019
1162019
Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80
M Goris, RS Magin, H Foyn, LM Myklebust, S Varland, R Ree, A Drazic, ...
Proceedings of the National Academy of Sciences 115 (17), 4405-4410, 2018
692018
Truncating variants in NAA15 are associated with variable levels of intellectual disability, autism spectrum disorder, and congenital anomalies
H Cheng, AV Dharmadhikari, S Varland, N Ma, D Domingo, R Kleyner, ...
The American Journal of Human Genetics 102 (5), 985-994, 2018
652018
Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency
T Ward, W Tai, S Morton, F Impens, P Van Damme, D Van Haver, ...
Circulation research 128 (8), 1156-1169, 2021
242021
N-terminal acetylation levels are maintained during acetyl-CoA deficiency in Saccharomyces cerevisiae
S Varland, H Aksnes, F Kryuchkov, F Impens, D Van Haver, V Jonckheere, ...
Molecular & Cellular Proteomics 17 (12), 2309-2323, 2018
242018
PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin
R Ree, L Kind, A Kaziales, S Varland, M Dai, K Richter, A Drazic, ...
Journal of Biological Chemistry 295 (49), 16713-16731, 2020
222020
The final maturation state of β-actin involves N-terminal acetylation by NAA80, not N-terminal arginylation by ATE1
A Drazic, E Timmerman, U Kajan, M Marie, S Varland, F Impens, ...
Journal of molecular biology 434 (2), 167397, 2022
152022
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
S Varland, RD Silva, I Kjosås, A Faustino, A Bogaert, M Billmann, ...
Nature communications 14 (1), 6774, 2023
142023
Identification of an alternatively spliced nuclear isoform of human N-terminal acetyltransferase Naa30
S Varland, LM Myklebust, SØ Goksøyr, N Glomnes, J Torsvik, JE Varhaug, ...
Gene 644, 27-37, 2018
142018
Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae
S Varland, T Arnesen
BMC Research Notes 11, 1-8, 2018
102018
Human NAA30 can rescue yeast mak3∆ mutant growth phenotypes
A Drazic, S Varland
Bioscience Reports 41 (3), BSR20202828, 2021
72021
A nonsense variant in the N‐terminal acetyltransferase NAA30 may be associated with global developmental delay and tracheal cleft
S Varland, KM Brønstad, SJ Skinner, T Arnesen
American Journal of Medical Genetics Part A 191 (9), 2402-2410, 2023
22023
N-terminal acetylation of actin by NAA80 impacts cell migration
H Aksnes, A Drazic, M Marie, S Varland, E Timmerman, H Foyn, ...
FEBS OPEN BIO 8, 396-396, 2018
2018
A yeast model for genetic variants in human NAA15 associated with autism spectrum disorder
S Varland, H Cheng, AVD Dharmadhikari, A Stray-Pedersen, GM Mancini, ...
FEBS OPEN BIO 8, 403-403, 2018
2018
Discovery of NAA80 as actin's N-terminal acetyltransferase-a novel regulator of cytoskeleton dynamics
A Drazic, H Aksnes, M Marie, M Boczkowska, S Varland, E Timmerman, ...
FEBS OPEN BIO 8, 409-409, 2018
2018
The N-terminal acetyltransferase NatC has a role in cellular stress response in yeast
S Varland, T Arnesen
YEAST 32, S130-S131, 2015
2015
Metabolic regulation of N-terminal acetylation in Saccharomyces cerevisiae
S Varland, P Van Damme, J Hollebeke, H Aksnes, K Gevaert, T Arnesen
27th International conference on Yeast Genetics and Molecular Biology …, 2015
2015
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