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Michael Sanguinetti
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A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
MC Sanguinetti, C Jiang, ME Curran, MT Keating
Cell 81 (2), 299-307, 1995
27431995
Coassembly of KvLQT1 and minK (IsK) proteins to form cardiac IKs potassium channel
MC Sanguinetti, ME Curran, A Zou, J Shen, PS Spector, DL Atkinson, ...
Nature 384, 1996
20321996
Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.
MC Sanguinetti, NK Jurkiewicz
The Journal of general physiology 96 (1), 195-215, 1990
1912*1990
CaV1. 2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
I Splawski, KW Timothy, LM Sharpe, N Decher, P Kumar, R Bloise, ...
Cell 119 (1), 19-31, 2004
17082004
hERG potassium channels and cardiac arrhythmia
MC Sanguinetti, M Tristani-Firouzi
Nature 440 (7083), 463-469, 2006
16212006
Molecular and cellular mechanisms of cardiac arrhythmias
MT Keating, MC Sanguinetti
Cell 104 (4), 569-580, 2001
11972001
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
GA Gutman, KG Chandy, S Grissmer, M Lazdunski, D Mckinnon, ...
Pharmacological reviews 57 (4), 473-508, 2005
11352005
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death
C Antzelevitch, GD Pollevick, JM Cordeiro, O Casis, MC Sanguinetti, ...
Circulation 115 (4), 442-449, 2007
10992007
A structural basis for drug-induced long QT syndrome
JS Mitcheson, J Chen, M Lin, C Culberson, MC Sanguinetti
Proceedings of the National Academy of Sciences 97 (22), 12329-12333, 2000
10742000
Mutations in the hminK gene cause long QT syndrome and suppress lKs function
I Splawski, M Tristani-Firouzi, MH Lehmann, MC Sanguinetti, MT Keating
Nature genetics 17 (3), 338-340, 1997
9481997
Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations
I Splawski, KW Timothy, N Decher, P Kumar, FB Sachse, AH Beggs, ...
Proceedings of the National Academy of Sciences 102 (23), 8089-8096, 2005
6882005
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
MC Sanguinetti, RS Kass
Circulation Research 55 (3), 336-348, 1984
6561984
Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ …
NK Jurkiewicz, MC Sanguinetti
Circulation research 72 (1), 75-83, 1993
6291993
Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.
MC Sanguinetti, ME Curran, PS Spector, MT Keating
Proceedings of the National Academy of Sciences 93 (5), 2208-2212, 1996
5481996
Fast inactivation causes rectification of the IKr channel.
PS Spector, ME Curran, A Zou, MT Keating, MC Sanguinetti
The Journal of general physiology 107 (5), 611-619, 1996
5001996
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels
GA Gutman, KG Chandy, JP Adelman, J Aiyar, DA Bayliss, DE Clapham, ...
Pharmacological reviews 55 (4), 583-586, 2003
4392003
Genetically defined therapy of inherited long-QT syndrome: correction of abnormal repolarization by potassium
SJ Compton, RL Lux, MR Ramsey, KR Strelich, MC Sanguinetti, LS Green, ...
Circulation 94 (5), 1018-1022, 1996
4031996
Drug‐induced torsades de pointes and implications for drug development
RR Fenichel, M Malik, C Antzelevitch, M Sanguinetti, DM Roden, ...
Journal of cardiovascular electrophysiology 15 (4), 475-495, 2004
3922004
De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero
K Hong, DR Piper, A Diaz-Valdecantos, J Brugada, A Oliva, ...
Cardiovascular research 68 (3), 433-440, 2005
3632005
Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K+ Channel: Open-Channel Block by Methanesulfonanilides
PS Spector, ME Curran, MT Keating, MC Sanguinetti
Circulation research 78 (3), 499-503, 1996
3631996
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Articles 1–20