| Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability T Kleefstra, JM Kramer, K Neveling, MH Willemsen, TS Koemans, ... The American Journal of Human Genetics 91 (1), 73-82, 2012 | 293 | 2012 |
| Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a JM Kramer, K Kochinke, MAW Oortveld, H Marks, D Kramer, EK de Jong, ... PLoS biology 9 (1), e1000569, 2011 | 241 | 2011 |
| Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan T Roscioli, EJ Kamsteeg, K Buysse, I Maystadt, J van Reeuwijk, ... Nature genetics 44 (5), 581-585, 2012 | 232 | 2012 |
| p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling EM Memmi, AG Sanarico, A Giacobbe, A Peschiaroli, V Frezza, ... Proceedings of the National Academy of Sciences 112 (11), 3499-3504, 2015 | 185 | 2015 |
| De novo mutations in the genome organizer CTCF cause intellectual disability A Gregor, M Oti, EN Kouwenhoven, J Hoyer, H Sticht, AB Ekici, ... The American Journal of Human Genetics 93 (1), 124-131, 2013 | 182 | 2013 |
| Genome-wide profiling of p63 DNA–binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus EN Kouwenhoven, SJ van Heeringen, JJ Tena, M Oti, BE Dutilh, ... PLoS genetics 6 (8), e1001065, 2010 | 182 | 2010 |
| Master regulatory role of p63 in epidermal development and disease E Soares, H Zhou Cellular and Molecular Life Sciences 75 (7), 1179-1190, 2018 | 179 | 2018 |
| p63–microRNA feedback in keratinocyte senescence P Rivetti di Val Cervo, AM Lena, M Nicoloso, S Rossi, M Mancini, H Zhou, ... Proceedings of the National Academy of Sciences 109 (4), 1133-1138, 2012 | 175 | 2012 |
| Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice HA Thomason, H Zhou, EN Kouwenhoven, GP Dotto, G Restivo, ... The Journal of clinical investigation 120 (5), 1561-1569, 2010 | 158 | 2010 |
| Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation EN Kouwenhoven, M Oti, H Niehues, SJ van Heeringen, J Schalkwijk, ... EMBO reports 16 (7), 863-878, 2015 | 157 | 2015 |
| Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder TS Koemans, T Kleefstra, MC Chubak, MH Stone, MRF Reijnders, ... PLoS genetics 13 (10), e1006864, 2017 | 156 | 2017 |
| ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis R Shalom-Feuerstein, AM Lena, H Zhou, S De La Forest Divonne, ... Cell Death & Differentiation 18 (5), 887-896, 2011 | 155 | 2011 |
| Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ... Nature communications 10 (1), 4928, 2019 | 138 | 2019 |
| Choices for induction of pluripotency: recent developments in human induced pluripotent stem cell reprogramming strategies M Brouwer, H Zhou, N Nadif Kasri Stem Cell Reviews and Reports 12, 54-72, 2016 | 114 | 2016 |
| Mutations in the epithelial cadherin-p120-catenin complex cause mendelian non-syndromic cleft lip with or without cleft palate LL Cox, TC Cox, LMM Uribe, Y Zhu, CT Richter, N Nidey, JM Standley, ... The American Journal of Human Genetics 102 (6), 1143-1157, 2018 | 106 | 2018 |
| Histone methylation by the Kleefstra syndrome protein EHMT1 mediates homeostatic synaptic scaling M Benevento, G Iacono, M Selten, W Ba, A Oudakker, M Frega, J Keller, ... Neuron 91 (2), 341-355, 2016 | 93 | 2016 |
| p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome G Ferone, MR Mollo, HA Thomason, D Antonini, H Zhou, R Ambrosio, ... Human molecular genetics 22 (3), 531-543, 2013 | 87 | 2013 |
| Uncleaved TFIIA is a substrate for taspase 1 and active in transcription H Zhou, S Spicuglia, JJD Hsieh, DJ Mitsiou, T Høiby, GJC Veenstra, ... Molecular and cellular biology, 2006 | 86 | 2006 |
| Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome G Ferone, HA Thomason, D Antonini, L De Rosa, B Hu, M Gemei, H Zhou, ... EMBO molecular medicine 4 (3), 192-205, 2012 | 84 | 2012 |
| Tooth agenesis and orofacial clefting: genetic brothers in arms? M Phan, F Conte, KD Khandelwal, CW Ockeloen, T Bartzela, T Kleefstra, ... Human genetics 135, 1299-1327, 2016 | 81 | 2016 |
Hans van BokhovenHoogleraar RadboudumcVerified email at radboudumc.nl
