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Christopher John Wilson
Christopher John Wilson
Stylus, Editas, Novartis, MIT, Arqule, Akceli
Verifisert e-postadresse på alum.mit.edu
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-307, 2012
76572012
Genome-wide location and function of DNA binding proteins
B Ren, F Robert, JJ Wyrick, O Aparicio, EG Jennings, I Simon, J Zeitlinger, ...
Science Signalling 290 (5500), 2306, 2000
27172000
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614-620, 2009
21672009
Bidirectional transport of amino acids regulates mTOR and autophagy
P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ...
Cell 136 (3), 521-534, 2009
19342009
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17112010
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
WE Dowdle, B Nyfeler, J Nagel, RA Elling, S Liu, E Triantafellow, ...
Nature cell biology 16 (11), 1069-1079, 2014
6422014
Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10
ML Maeder, M Stefanidakis, CJ Wilson, R Baral, LA Barrera, ...
Nature medicine 25 (2), 229-233, 2019
6082019
Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor
SM Maira, S Pecchi, A Huang, M Burger, M Knapp, D Sterker, C Schnell, ...
Molecular cancer therapeutics 11 (2), 317-328, 2012
5932012
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases
CJ Hengartner, VE Myer, SM Liao, CJ Wilson, SS Koh, RA Young
Molecular cell 2 (1), 43-54, 1998
5641998
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling.
CJ Wilson, DM Chao, AN Imbalzano, GR Schnitzler, RE Kingston, ...
Cell 84 (2), 235, 1996
5221996
Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials
C Fritsch, A Huang, C Chatenay-Rivauday, C Schnell, A Reddy, M Liu, ...
Molecular cancer therapeutics 13 (5), 1117-1129, 2014
4672014
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor
V Guagnano, A Kauffmann, S Wöhrle, C Stamm, M Ito, L Barys, A Pornon, ...
Cancer Discovery, 2012
3502012
Structure of the CAP-DNA complex at 2.5 Å resolution: a complete picture of the protein-DNA interface
G Parkinson, C Wilson, A Gunasekera, YW Ebright, RE Ebright, ...
Journal of molecular biology 260 (3), 395-408, 1996
3301996
Association of MTOR mutations with developmental brain disorders, including megalencephaly, focal cortical dysplasia, and pigmentary mosaicism
GM Mirzaa, CD Campbell, N Solovieff, CP Goold, LA Jansen, S Menon, ...
JAMA neurology 73 (7), 836-845, 2016
2582016
Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication
J Borawski, P Troke, X Puyang, V Gibaja, SC Zhao, C Mickanin, ...
Journal of virology 83 (19), 10058-10074, 2009
2102009
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling
X Cai, Y Xu, AK Cheung, RC Tomlinson, A Alcázar-Román, L Murphy, ...
Chemistry & biology 20 (7), 912-921, 2013
2002013
Lehá r, J., Kryukov, GV, Sonkin, D., et al.(2012)
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer …, 0
184
Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations
SM Brachmann, J Kleylein-Sohn, S Gaulis, A Kauffmann, MJJ Blommers, ...
Molecular cancer therapeutics 11 (8), 1747-1757, 2012
1422012
A strategy for rapid, high-confidence protein identification
J Qin, D Fenyö, Y Zhao, W William, DM Chao, CJ Wilson, RA Young, ...
Analytical chemistry 69 (19), 3995-4001, 1997
1401997
Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers
PD Garcia, JL Langowski, Y Wang, M Chen, J Castillo, C Fanton, M Ison, ...
Clinical cancer research 20 (7), 1834-1845, 2014
1332014
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Artikler 1–20