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Upul Deepthike Halambage (Halambage Upul Deepthike)
Upul Deepthike Halambage (Halambage Upul Deepthike)
Aprecia Pharmaceuticals, LLC
Verifisert e-postadresse på aprecia.com
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Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly
AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, ...
PLoS pathogens 10 (10), e1004459, 2014
2782014
Roles of capsid-interacting host factors in multimodal inhibition of HIV-1 by PF74
A Saito, D Ferhadian, GA Sowd, E Serrao, J Shi, UD Halambage, S Teng, ...
Journal of virology 90 (12), 5808-5823, 2016
912016
HIV-1 resistance to the capsid-targeting inhibitor PF74 results in altered dependence on host factors required for virus nuclear entry
J Zhou, AJ Price, UD Halambage, LC James, C Aiken
Journal of virology 89 (17), 9068-9079, 2015
662015
Unlike PAHs from Exxon Valdez crude oil, PAHs from Gulf of Alaska coals are not readily bioavailable
HU Deepthike, R Tecon, G Kooten, JR Meer, H Harms, M Wells, J Short
Environmental science & technology 43 (15), 5864-5870, 2009
482009
Compensatory substitutions in the HIV-1 capsid reduce the fitness cost associated with resistance to a capsid-targeting small-molecule inhibitor
J Shi, J Zhou, UD Halambage, VB Shah, MJ Burse, H Wu, WS Blair, ...
Journal of virology 89 (1), 208-219, 2015
372015
A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing
MA Siddiqui, A Saito, UD Halambage, D Ferhadian, DK Fischer, ...
Journal of virology 93 (16), 10.1128/jvi. 00706-19, 2019
342019
Inhibition of HIV-1 maturation via small-molecule targeting of the amino-terminal domain in the viral capsid protein
W Wang, J Zhou, UD Halambage, KA Jurado, AV Jamin, Y Wang, ...
Journal of virology 91 (9), 10.1128/jvi. 02155-16, 2017
302017
Comparison of naphthalene bioavailability determined by whole-cell biosensing and availability determined by extraction with Tenax
S Kohlmeier, M Mancuso, U Deepthike, R Tecon, JR van der Meer, ...
Environmental pollution 156 (3), 803-808, 2008
302008
Temperature-sensitive microcapsules with variable optical signatures based on incorporation of quantum dots into a highly biocompatible hydrogel
D Hardison, HU Deepthike, W Senevirathna, T Pathirathne, M Wells
Journal of Materials Chemistry 18 (44), 5368-5375, 2008
212008
Response to Comment on “Unlike PAHs from Exxon Valdez Crude Oil, PAHs from Gulf of Alaska Coals are not Readily Bioavailable”
HU Deepthike, R Tecon, GKV Kooten, JR Meer, H Harms, M Wells, ...
Environmental science & technology 44 (6), 2212-2213, 2010
122010
Microplate-based assay for identifying small molecules that bind a specific intersubunit interface within the assembled HIV-1 capsid
UD Halambage, JP Wong, BJ Melancon, CW Lindsley, C Aiken
Antimicrobial Agents and Chemotherapy 59 (9), 5190-5195, 2015
52015
696 James LC. 2014. Host cofactors and pharmacologic ligands share an essential interface in HIV-697 1 capsid that is lost upon disassembly
AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, ...
PLoS Pathog 10, e1004459, 0
3
Design, Synthesis, and Biological Activity of Novel Octahydro-1Hpyrrolo [3, 2-c] pyridine Derivatives as CC Chemokine Receptor Type 5 (CCR5) Antagonists
Y Wang, U Halambage, C Zeng, L Hu
Chinese Journal of Organic Chemistry 37 (9), 2385, 2017
2017
MS05. O05
A Price, D Jacques, S Essig, T Elliott, U Halambage, J Chin, C Aiken, ...
Acta Cryst 70, C120, 2014
2014
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