| Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma N Auslander, G Zhang, JS Lee, DT Frederick, B Miao, T Moll, T Tian, ... Nature medicine 24 (10), 1545-1549, 2018 | 554 | 2018 |
| Room-temperature tunnel magnetoresistance and spin-polarized tunneling through an organic semiconductor barrier TS Santos, JS Lee, P Migdal, IC Lekshmi, B Satpati, JS Moodera Physical review letters 98 (1), 016601, 2007 | 478 | 2007 |
| UVB-induced tumor heterogeneity diminishes immune response in melanoma Y Wolf, O Bartok, S Patkar, GB Eli, S Cohen, K Litchfield, R Levy, ... Cell 179 (1), 219-235. e21, 2019 | 322 | 2019 |
| A platform of synthetic lethal gene interaction networks reveals that the GNAQ uveal melanoma oncogene controls the hippo pathway through FAK X Feng, N Arang, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, S Lubrano, ... Cancer cell 35 (3), 457-472. e5, 2019 | 211 | 2019 |
| Urea cycle dysregulation generates clinically relevant genomic and biochemical signatures JS Lee, L Adler, H Karathia, N Carmel, S Rabinovich, N Auslander, ... Cell 174 (6), 1559-1570. e22, 2018 | 209 | 2018 |
| Multiomics prediction of response rates to therapies to inhibit programmed cell death 1 and programmed cell death 1 ligand 1 JS Lee, E Ruppin JAMA oncology 5 (11), 1614-1618, 2019 | 200 | 2019 |
| Targeting the Warburg effect via LDHA inhibition engages ATF 4 signaling for cancer cell survival G Pathria, DA Scott, Y Feng, J Sang Lee, Y Fujita, G Zhang, AD Sahu, ... The EMBO journal 37 (20), e99735, 2018 | 118 | 2018 |
| Harnessing synthetic lethality to predict the response to cancer treatment JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ... Nature communications 9 (1), 2546, 2018 | 116 | 2018 |
| Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma MH Hung, JS Lee, C Ma, LP Diggs, S Heinrich, CW Chang, L Ma, ... Nature communications 12 (1), 1455, 2021 | 114 | 2021 |
| Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma S Kalaora, JS Lee, E Barnea, R Levy, P Greenberg, M Alon, G Yagel, ... Nature communications 11 (1), 896, 2020 | 110 | 2020 |
| Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer H Gibori, S Eliyahu, A Krivitsky, D Ben-Shushan, Y Epshtein, G Tiram, ... Nature communications 9 (1), 16, 2018 | 77 | 2018 |
| Synthetic lethality-mediated precision oncology via the tumor transcriptome JS Lee, NU Nair, G Dinstag, L Chapman, Y Chung, K Wang, S Sinha, ... Cell 184 (9), 2487-2502. e13, 2021 | 69 | 2021 |
| Translational reprogramming marks adaptation to asparagine restriction in cancer G Pathria, JS Lee, E Hasnis, K Tandoc, DA Scott, S Verma, Y Feng, ... Nature cell biology 21 (12), 1590-1603, 2019 | 69 | 2019 |
| Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors R Keshet, JS Lee, L Adler, M Iraqi, Y Ariav, LQJ Lim, S Lerner, ... Nature Cancer 1 (9), 894-908, 2020 | 49 | 2020 |
| Acid-induced downregulation of ASS1 contributes to the maintenance of intracellular pH in cancer A Silberman, O Goldman, O Boukobza Assayag, A Jacob, S Rabinovich, ... Cancer research 79 (3), 518-533, 2019 | 43 | 2019 |
| AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer A Noronha, N Belugali Nataraj, JS Lee, B Zhitomirsky, Y Oren, S Oster, ... Cancer discovery 12 (11), 2666-2683, 2022 | 41 | 2022 |
| A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature communications 12 (1), 6512, 2021 | 39 | 2021 |
| Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans S Sinha, KA Mitchell, A Zingone, E Bowman, N Sinha, AA Schäffer, ... Nature Cancer 1 (1), 112-121, 2020 | 39 | 2020 |
| Anti-tumor effects of anti-PD-1 antibody, pembrolizumab, in humanized NSG PDX mice xenografted with dedifferentiated liposarcoma B Choi, JS Lee, SJ Kim, D Hong, JB Park, KY Lee Cancer letters 478, 56-69, 2020 | 38 | 2020 |
| Beyond synthetic lethality: charting the landscape of pairwise gene expression states associated with survival in cancer A Magen, AD Sahu, JS Lee, M Sharmin, A Lugo, JS Gutkind, AA Schäffer, ... Cell reports 28 (4), 938-948. e6, 2019 | 36 | 2019 |
