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Harvey W. Smith
Harvey W. Smith
Rosalind and Morris Goodman Cancer Institute, McGill University
Verifisert e-postadresse på mcgill.ca
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Regulation of cell signalling by uPAR
HW Smith, CJ Marshall
Nature reviews Molecular cell biology 11 (1), 23-36, 2010
10822010
Stimulation of the weak ATPase activity of human hsp90 by a client protein
SH McLaughlin, HW Smith, SE Jackson
Journal of molecular biology 315 (4), 787-798, 2002
3352002
uPAR promotes formation of the p130Cas–Crk complex to activate Rac through DOCK180
HW Smith, P Marra, CJ Marshall
The journal of cell biology 182 (4), 777-790, 2008
1352008
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer
G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ...
Nature communications 7 (1), 12156, 2016
1182016
Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program
A Hirukawa, HW Smith, D Zuo, CR Dufour, P Savage, N Bertos, ...
Nature communications 9 (1), 2547, 2018
792018
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
E Ngan, K Stoletov, HW Smith, J Common, WJ Muller, JD Lewis, ...
Nature communications 8 (1), 15059, 2017
732017
Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis
R Marcotte, HW Smith, V Sanguin-Gendreau, RV McDonough, WJ Muller
Proceedings of the National Academy of Sciences 109 (8), 2808-2813, 2012
572012
KIBRA (WWC1) Is a metastasis suppressor gene affected by chromosome 5q loss in triple-negative breast cancer
JF Knight, VYC Sung, E Kuzmin, AL Couzens, DA de Verteuil, ...
Cell reports 22 (12), 3191-3205, 2018
472018
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
A Hirukawa, S Singh, J Wang, JP Rennhack, M Swiatnicki, ...
Cell reports 29 (2), 249-257. e8, 2019
352019
Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in …
T Rao, JJ Ranger, HW Smith, SH Lam, L Chodosh, WJ Muller
Breast Cancer Research 16, 1-14, 2014
352014
Transgenic mouse models—A seminal breakthrough in oncogene research
HW Smith, WJ Muller
Cold Spring Harbor Protocols 2013 (12), pdb. top069765, 2013
292013
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis
HW Smith, A Hirukawa, V Sanguin-Gendreau, I Nandi, CR Dufour, D Zuo, ...
Nature Communications 10 (1), 2901, 2019
282019
An ErbB2 splice variant lacking exon 16 drives lung carcinoma
HW Smith, L Yang, C Ling, A Walsh, VD Martinez, J Boucher, D Zuo, ...
Proceedings of the National Academy of Sciences 117 (33), 20139-20148, 2020
152020
Integration of distinct ShcA signaling complexes promotes breast tumor growth and tyrosine kinase inhibitor resistance
JR Ha, R Ahn, HW Smith, V Sabourin, S Hébert, E Cepeda Cañedo, ...
Molecular Cancer Research 16 (5), 894-908, 2018
142018
Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
AH Mohammad, SH Kim, N Bertos, W El-Assaad, I Nandi, H Smith, J Yang, ...
Molecular Cancer Research 18 (10), 1477-1490, 2020
112020
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression
I Nandi, HW Smith, V Sanguin-Gendreau, L Ji, A Pacis, V Papavasiliou, ...
The Journal of Clinical Investigation 133 (7), 2023
72023
ARF6 controls RHOB targeting to endosomes regulating cancer cell invasion
K Zaoui, HW Smith, M Park, S Duhamel
Molecular & Cellular Oncology 7 (5), 1766932, 2020
22020
Abstract B007: c-Src and PRC2 activity in ErbB2-driven mammary tumorigenesis and acquired resistance to ErbB2-targeted therapy
HW Smith, A Hirukawa, V Sanguin-Gendreau, D Zuo, WJ Muller
Molecular Cancer Research 11 (10_Supplement), B007-B007, 2013
22013
Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
CR Dufour, H Xia, W B’chir, MC Perry, U Kuzmanov, A Gainullina, ...
Communications Biology 5 (1), 955, 2022
12022
Ezh2 promotes mammary tumor initiation through epigenetic regulation of the Wnt and mTORC1 signaling pathways
L Liu, B Xiao, A Hirukawa, HW Smith, D Zuo, V Sanguin-Gendreau, ...
Proceedings of the National Academy of Sciences 120 (33), e2303010120, 2023
2023
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