Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. SM Keyse, RM Tyrrell Proceedings of the National Academy of Sciences 86 (1), 99-103, 1989 | 1623 | 1989 |
Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene JB Li, JM Gerdes, CJ Haycraft, Y Fan, TM Teslovich, H May-Simera, H Li, ... Cell 117 (4), 541-552, 2004 | 1070* | 2004 |
Protein phosphatases and the regulation of mitogen-activated protein kinase signalling SM Keyse Current opinion in cell biology 12 (2), 186-192, 2000 | 1029 | 2000 |
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases DM Owens, SM Keyse Oncogene 26 (22), 3203-3213, 2007 | 995 | 2007 |
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase SM Keyse, EA Emslie Nature 359 (6396), 644-647, 1992 | 796 | 1992 |
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry A Brunet, D Roux, P Lenormand, S Dowd, S Keyse, J Pouysségur The EMBO journal 18 (3), 664-674, 1999 | 752 | 1999 |
Dual‐specificity MAP kinase phosphatases (MKPs) Shaping the outcome of MAP kinase signalling CJ Caunt, SM Keyse The FEBS journal 280 (2), 489-504, 2013 | 587 | 2013 |
Dual-specificity MAP kinase phosphatases (MKPs) and cancer SM Keyse Cancer and Metastasis Reviews 27, 253-261, 2008 | 571 | 2008 |
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual‐specificity phosphatase. LA Groom, AA Sneddon, DR Alessi, S Dowd, SM Keyse The EMBO journal 15 (14), 3621-3632, 1996 | 502 | 1996 |
Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines DR Alessi, N Gomez, G Moorhead, T Lewis, SM Keyse, P Cohen Current Biology 5 (3), 283-295, 1995 | 464 | 1995 |
Diverse physiological functions for dual-specificity MAP kinase phosphatases RJ Dickinson, SM Keyse Journal of cell science 119 (22), 4607-4615, 2006 | 422 | 2006 |
The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus … DR Alessi, C Smythe, SM Keyse ONCOGENE-BASINGSTOKE- 8, 2015-2015, 1993 | 418 | 1993 |
New trends in photobiology the interaction of UVA radiation with cultured cells RM Tyrrell, SM Keyse Journal of Photochemistry and Photobiology B: Biology 4 (4), 349-361, 1990 | 348 | 1990 |
An emerging family of dual specificity MAP kinase phosphatases SM Keyse Biochimica et Biophysica Acta-Molecular Cell Research 1265 (2), 152-160, 1995 | 341 | 1995 |
Distinct Binding Determinants for ERK2/p38α and JNK MAP Kinases Mediate Catalytic Activation and Substrate Selectivity of MAP Kinase Phosphatase-1* 210 DN Slack, OM Seternes, M Gabrielsen, SM Keyse Journal of Biological Chemistry 276 (19), 16491-16500, 2001 | 323 | 2001 |
Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32-kDa stress protein in normal human skin fibroblasts. SM Keyse, RM Tyrrell Journal of Biological Chemistry 262 (30), 14821-14825, 1987 | 286 | 1987 |
Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts SM Keyse, T Lee Ann Applegate, Y Tromvoukis, RM Tyrrell Molecular and cellular biology 10 (9), 4967-4969, 1990 | 261 | 1990 |
Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling A Glading, F Uberall, SM Keyse, DA Lauffenburger, A Wells Journal of Biological Chemistry 276 (26), 23341-23348, 2001 | 246 | 2001 |
The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs) AM Kidger, SM Keyse Seminars in cell & developmental biology 50, 125-132, 2016 | 232 | 2016 |
Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5 M Mandl, DN Slack, SM Keyse Molecular and cellular biology 25 (5), 1830-1845, 2005 | 229 | 2005 |