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Martin J. Simard
Martin J. Simard
Professor, CHU de Québec-Université Laval Research Center
Verifisert e-postadresse på crhdq.ulaval.ca - Startside
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Argonaute proteins: key players in RNA silencing
G Hutvagner, MJ Simard
Nature reviews Molecular cell biology 9 (1), 22-32, 2008
17462008
Sequence-specific inhibition of small RNA function
G Hutvágner, MJ Simard, CC Mello, PD Zamore
PLoS biology 2 (4), e98, 2004
8522004
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi
E Yigit, PJ Batista, Y Bei, KM Pang, CCG Chen, NH Tolia, L Joshua-Tor, ...
Cell 127 (4), 747-757, 2006
7472006
Human let-7a miRNA blocks protein production on actively translating polyribosomes
S Nottrott, MJ Simard, JD Richter
Nature structural & molecular biology 13 (12), 1108-1114, 2006
6412006
Role for miR-204 in human pulmonary arterial hypertension
A Courboulin, R Paulin, NJ Giguère, N Saksouk, T Perreault, J Meloche, ...
Journal of Experimental Medicine 208 (3), 535-548, 2011
5952011
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
PD Zamore, G Hutvágner, D Schwarz, M Simard
US Patent 7,750,144, 2010
430*2010
Function, targets, and evolution of Caenorhabditis elegans piRNAs
MP Bagijn, LD Goldstein, A Sapetschnig, EM Weick, S Bouasker, ...
Science 337 (6094), 574-578, 2012
3932012
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
L Zhong, MJ Simard, J Huot
The FASEB Journal 32 (8), 4070-4084, 2018
1822018
A member of the polymerase β nucleotidyltransferase superfamily is required for RNA interference in C. elegans
CCG Chen, MJ Simard, H Tabara, DR Brownell, JA McCollough, ...
Current Biology 15 (4), 378-383, 2005
1292005
MicroRNA‐19a enhances proliferation of bronchial epithelial cells by targeting TGFβR2 gene in severe asthma
I Haj‐Salem, R Fakhfakh, JC Bérubé, E Jacques, S Plante, MJ Simard, ...
Allergy 70 (2), 212-219, 2015
1202015
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans
G Jannot, S Bajan, NJ Giguere, S Bouasker, IH Banville, S Piquet, ...
EMBO reports 12 (6), 581-586, 2011
1042011
SRp30c is a repressor of 3′ splice site utilization
MJ Simard, B Chabot
Molecular and cellular biology 22 (12), 4001-4010, 2002
972002
Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression
AL Pin, F Houle, P Fournier, M Guillonneau, ÉR Paquet, MJ Simard, ...
Journal of Biological Chemistry 287 (36), 30541-30551, 2012
942012
Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2
A Vasquez-Rifo, G Jannot, J Armisen, M Labouesse, SIA Bukhari, ...
PLoS One 7 (3), e33750, 2012
882012
Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA‐guided gene silencing in vivo
M Quévillon Huberdeau, DM Zeitler, J Hauptmann, A Bruckmann, ...
The EMBO journal 36 (14), 2088-2106, 2017
862017
The microRNA pathway controls germ cell proliferation and differentiation in C. elegans
SIA Bukhari, A Vasquez-Rifo, D Gagné, ER Paquet, M Zetka, C Robert, ...
Cell research 22 (6), 1034-1045, 2012
762012
The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans
GD Bossé, S Rüegger, MC Ow, A Vasquez-Rifo, EL Rondeau, VR Ambros, ...
Molecular cell 50 (2), 281-287, 2013
722013
miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF
AL Pin, F Houle, M Guillonneau, ER Paquet, MJ Simard, J Huot
Angiogenesis 15, 593-608, 2012
692012
Somatic and germline microRNAs form distinct silencing complexes to regulate their target mRNAs differently
A Dallaire, PM Frédérick, MJ Simard
Developmental cell 47 (2), 239-247. e4, 2018
602018
Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans
G Jannot, MEL Boisvert, IH Banville, MJ Simard
Rna 14 (5), 829-835, 2008
602008
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Artikler 1–20