High‐throughput screening and small animal models, where are we? J Giacomotto, L Ségalat British journal of pharmacology 160 (2), 204-216, 2010 | 371 | 2010 |
Metabotyping of Caenorhabditis elegans reveals latent phenotypes BJ Blaise, J Giacomotto, B Elena, ME Dumas, P Toulhoat, L Ségalat, ... Proceedings of the National Academy of Sciences 104 (50), 19808-19812, 2007 | 133 | 2007 |
Caveolae protect notochord cells against catastrophic mechanical failure during development YW Lim, HP Lo, C Ferguson, N Martel, J Giacomotto, GA Gomez, TE Hall, ... Current Biology 27 (13), 1968-1981. e7, 2017 | 84 | 2017 |
Neurexins in autism and schizophrenia—a review of patient mutations, mouse models and potential future directions A Tromp, B Mowry, J Giacomotto Molecular psychiatry 26 (3), 747-760, 2021 | 79 | 2021 |
Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study S Periyasamy, S John, R Padmavati, P Rajendren, P Thirunavukkarasu, ... JAMA psychiatry 76 (10), 1026-1034, 2019 | 68 | 2019 |
Metabolic Profiling Strategy of Caenorhabditis elegans by Whole-Organism Nuclear Magnetic Resonance BJ Blaise, J Giacomotto, MN Triba, P Toulhoat, M Piotto, L Emsley, ... Journal of proteome research 8 (5), 2542-2550, 2009 | 59 | 2009 |
Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy J Giacomotto, N Brouilly, L Walter, MC Mariol, J Berger, L Segalat, ... Human molecular genetics 22 (22), 4562-4578, 2013 | 58 | 2013 |
miR‐124 Contributes to the functional maturity of microglia AJ Svahn, J Giacomotto, MB Graeber, S Rinkwitz, TS Becker Developmental neurobiology 76 (5), 507-518, 2016 | 57 | 2016 |
Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish Z Butti, YE Pan, J Giacomotto, SA Patten Communications biology 4 (1), 792, 2021 | 53 | 2021 |
Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus SWA Himaya, AH Jin, S Dutertre, J Giacomotto, H Mohialdeen, I Vetter, ... Journal of Proteome Research 14 (10), 4372-4381, 2015 | 47 | 2015 |
Effective heritable gene knockdown in zebrafish using synthetic microRNAs J Giacomotto, S Rinkwitz, TS Becker Nature communications 6 (1), 7378, 2015 | 44 | 2015 |
Blocking of Striated Muscle Degeneration by Serotonin in C. elegans M Carre-Pierrat, MC Mariol, L Chambonnier, A Laugraud, F Heskia, ... Journal of Muscle Research & Cell Motility 27, 253-258, 2006 | 44 | 2006 |
Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages AS Laird, N Mackovski, S Rinkwitz, TS Becker, J Giacomotto Human Molecular Genetics 25 (9), 1728-1738, 2016 | 39 | 2016 |
Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression J Djiotsa, V Verbruggen, J Giacomotto, M Ishibashi, E Manning, ... BMC developmental biology 12, 1-16, 2012 | 39 | 2012 |
Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy J Giacomotto, C Pertl, C Borrel, MC Walter, S Bulst, B Johnsen, DL Baillie, ... Human molecular genetics 18 (21), 4089-4101, 2009 | 38 | 2009 |
Brain-wide visual habituation networks in wild type and fmr1 zebrafish E Marquez-Legorreta, L Constantin, M Piber, IA Favre-Bulle, MA Taylor, ... Nature Communications 13 (1), 895, 2022 | 37 | 2022 |
Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies RS Gormal, P Padmanabhan, R Kasula, AT Bademosi, S Coakley, ... Proceedings of the National Academy of Sciences 117 (48), 30476-30487, 2020 | 36 | 2020 |
Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish J Giacomotto, AP Carroll, S Rinkwitz, B Mowry, MJ Cairns, TS Becker Translational psychiatry 6 (5), e818-e818, 2016 | 25 | 2016 |
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle HP Lo, YW Lim, Z Xiong, N Martel, C Ferguson, N Ariotti, J Giacomotto, ... Journal of Cell Biology 220 (12), e201905065, 2021 | 23 | 2021 |
Caenorhabditis elegans as a chemical screening tool for the study of neuromuscular disorders. Manual and semi-automated methods J Giacomotto, L Ségalat, M Carre-Pierrat, K Gieseler Methods 56 (1), 103-113, 2012 | 23 | 2012 |