Hemoglobin variants: biochemical properties and clinical correlates CS Thom, CF Dickson, DA Gell, MJ Weiss Cold Spring Harbor perspectives in medicine 3 (3), a011858, 2013 | 311 | 2013 |
IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis DL Mallery, CL Marquez, WA McEwan, CF Dickson, DA Jacques, ... Elife 7, e35335, 2018 | 135 | 2018 |
Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21. AJ Fletcher, DL Mallery, RE Watkinson, CF Dickson, J Leo C. Proc. Natl. Acad. Sci. U.S.A. 112 (32), 10014-9, 2015 | 100 | 2015 |
IsdB-dependent Hemoglobin Binding Is Required for Acquisition of Heme by Staphylococcus aureus G Pishchany, JR Sheldon, CF Dickson, MT Alam, TD Read, DA Gell, ... The Journal of infectious diseases 209 (11), 1764-1772, 2014 | 83 | 2014 |
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH KK Kumar, DA Jacques, G Pishchany, T Caradoc-Davies, T Spirig, ... Journal of Biological Chemistry 286 (44), 38439-38447, 2011 | 72 | 2011 |
Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21 C Dickson, AJ Fletcher, M Vaysburd, JC Yang, DL Mallery, J Zeng, ... Elife 7, e32660, 2018 | 66 | 2018 |
Staphylococcus aureus uses a novel multidomain receptor to break apart human hemoglobin and steal its heme T Spirig, GR Malmirchegini, J Zhang, SA Robson, M Sjodt, M Liu, ... Journal of Biological Chemistry 288 (2), 1065-1078, 2013 | 60 | 2013 |
Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus*♦ CF Dickson, KK Kumar, DA Jacques, GR Malmirchegini, T Spirig, ... Journal of Biological Chemistry 289 (10), 6728-6738, 2014 | 47 | 2014 |
Target-induced clustering activates Trim-Away of pathogens and proteins J Zeng, AF Santos, AS Mukadam, M Osswald, DA Jacques, CF Dickson, ... Nature structural & molecular biology 28 (3), 278-289, 2021 | 34 | 2021 |
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases L Kiss, J Zeng, CF Dickson, DL Mallery, JC Yang, SH McLaughlin, ... Nature communications 10 (1), 4502, 2019 | 30 | 2019 |
The PRE-derived NMR model of the 38.8-kDa tri-domain IsdH protein from Staphylococcus aureus suggests that it adaptively recognizes human hemoglobin M Sjodt, R Macdonald, T Spirig, AH Chan, CF Dickson, M Fabian, ... Journal of molecular biology 428 (6), 1107-1129, 2016 | 24 | 2016 |
The Staphylococcus aureus protein IsdH inhibits host hemoglobin scavenging to promote heme acquisition by the pathogen KL Sæderup, K Stødkilde, JH Graversen, CF Dickson, A Etzerodt, ... Journal of Biological Chemistry 291 (46), 23989-23998, 2016 | 21 | 2016 |
The structure of haemoglobin bound to the haemoglobin receptor IsdH from Staphylococcus aureus shows disruption of the native α-globin haem pocket CF Dickson, DA Jacques, RT Clubb, JM Guss, DA Gell Acta Crystallographica Section D: Biological Crystallography 71 (6), 1295-1306, 2015 | 20 | 2015 |
AHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded state K Krishna Kumar, CF Dickson, MJ Weiss, JP Mackay, DA Gell Biochemical Journal 432 (2), 275-282, 2010 | 16 | 2010 |
α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond CF Dickson, AM Rich, WMH D'Avigdor, DAT Collins, JA Lowry, TL Mollan, ... Journal of Biological Chemistry 288 (27), 19986-20001, 2013 | 14 | 2013 |
Evasion of cGAS and TRIM5 defines pandemic HIV L Zuliani-Alvarez, ML Govasli, J Rasaiyaah, C Monit, SO Perry, ... Nature Microbiology 7 (11), 1762-1776, 2022 | 10 | 2022 |
Normal and abnormal hemoglobins CS Thom, CF Dickson, JS Olson, DA Gell, M Weiss Hematology and Oncology of Infancy and Childhood. 8th ed. Philadelphia …, 2015 | 10 | 2015 |
Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy D Lau, JC Walsh, CF Dickson, A Tuckwell, JH Stear, DJB Hunter, ... Analytical Chemistry 93 (8), 3786-3793, 2021 | 5 | 2021 |
Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV L Zuliani Alvarez, ML Govasli, J Rasaiyaah, C Monit, SO Perry, ... bioRxiv, 2022.01. 21.477263, 2022 | 1 | 2022 |
Substrate-induced clustering activates Trim-Away of pathogens and proteins J Zeng, AF Santos, A Mukadam, M Osswald, J Luptak, D Jacques, ... bioRxiv, 2020.07. 28.225359, 2020 | 1 | 2020 |