| cAMP analog mapping of Epac1 and cAMP kinase: discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension AE Christensen, F Selheim, J de Rooij, S Dremier, F Schwede, KK Dao, ... Journal of Biological Chemistry 278 (37), 35394-35402, 2003 | 455 | 2003 |
| cAMP effector mechanisms. Novel twists for an ‘old’signaling system R Kopperud, C Krakstad, F Selheim, SO Døskeland FEBS letters 546 (1), 121-126, 2003 | 270 | 2003 |
| The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling M Chekenya, C Krakstad, A Svendsen, IA Netland, V Staalesen, ... Oncogene 27 (39), 5182-5194, 2008 | 187 | 2008 |
| Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc−, leading to glutathione depletion L Sleire, BS Skeie, IA Netland, HE Førde, E Dodoo, F Selheim, L Leiss, ... Oncogene 34 (49), 5951-5959, 2015 | 155 | 2015 |
| A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes L Herfindal, L Oftedal, F Selheim, M Wahlsten, K Sivonen, SO Døskeland Toxicon 46 (3), 252-260, 2005 | 90 | 2005 |
| Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide BO Jensen, F Selheim, SO Døskeland, ARL Gear, H Holmsen Blood 104 (9), 2775-2782, 2004 | 80 | 2004 |
| Identification of functional VEGF receptors on human platelets F Selheim, H Holmsen, FS Vassbotn FEBS letters 512 (1-3), 107-110, 2002 | 78 | 2002 |
| Marine benthic cyanobacteria contain apoptosis-inducing activity synergizing with daunorubicin to kill leukemia cells, but not cardiomyocytes L Oftedal, F Selheim, M Wahlsten, K Sivonen, SO Døskeland, L Herfindal Marine drugs 8 (10), 2659-2672, 2010 | 63 | 2010 |
| Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients M Hernandez-Valladares, E Aasebø, O Mjaavatten, M Vaudel, Ø Bruserud, ... Biological procedures online 18, 1-10, 2016 | 61 | 2016 |
| A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins J Jokela, L Herfindal, M Wahlsten, P Permi, F Selheim, V Vasconçelos, ... ChemBioChem 11 (11), 1594-1599, 2010 | 56 | 2010 |
| Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells I Nepstad, KJ Hatfield, IS Grønningsæter, E Aasebø, ... Signal transduction and targeted therapy 4 (1), 20, 2019 | 51 | 2019 |
| Microcystin produces disparate effects on liver cells in a dose dependent manner. L Herfindal, F Selheim Mini Reviews in Medicinal Chemistry 6 (3), 279-285, 2006 | 51 | 2006 |
| Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and OATP1B1 L Herfindal, L Myhren, R Kleppe, C Krakstad, F Selheim, J Jokela, ... Molecular Pharmaceutics 8 (2), 360-367, 2011 | 41 | 2011 |
| Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival MA Rahman, A Gras Navarro, J Brekke, A Engelsen, C Bindesbøll, ... British journal of cancer 121 (7), 545-555, 2019 | 38 | 2019 |
| PI 3-kinase signalling in platelets: the significance of synergistic, autocrine stimulation F Selheim, Holm Holmsen, Flemming S. Vassbotn Platelets 11 (2), 69-82, 2000 | 38 | 2000 |
| The progression of acute myeloid leukemia from first diagnosis to chemoresistant relapse: A comparison of proteomic and phosphoproteomic profiles E Aasebø, FS Berven, R Hovland, SO Døskeland, Ø Bruserud, F Selheim, ... Cancers 12 (6), 1466, 2020 | 37 | 2020 |
| Increased microvascular permeability in mice lacking Epac1 (Rapgef3) RK Kopperud, CB Rygh, TV Karlsen, C Krakstad, R Kleppe, EA Hoivik, ... Acta physiologica 219 (2), 441-452, 2017 | 37 | 2017 |
| Performance of super‐SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines E Aasebø, M Vaudel, O Mjaavatten, G Gausdal, A Van der Burgh, ... Proteomics 14 (17-18), 1971-1976, 2014 | 36 | 2014 |
| Freezing effects on the acute myeloid leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows E Aasebø, O Mjaavatten, M Vaudel, Y Farag, F Selheim, F Berven, ... Journal of proteomics 145, 214-225, 2016 | 35 | 2016 |
| Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia E Aasebø, FS Berven, S Bartaula-Brevik, T Stokowy, R Hovland, ... Cancers 12 (3), 709, 2020 | 34 | 2020 |
Stein Ove DøskelandProfessor of Biomedicine, University of BergenVerified email at uib.no
