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Dean Clift
Dean Clift
MRC Laboratory of Molecular Biology
Verifisert e-postadresse på mrc-lmb.cam.ac.uk
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A method for the acute and rapid degradation of endogenous proteins
D Clift, WA McEwan, LI Labzin, V Konieczny, B Mogessie, LC James, ...
Cell 171 (7), 1692-1706. e18, 2017
4092017
Restarting life: fertilization and the transition from meiosis to mitosis
D Clift, M Schuh
Nature reviews Molecular cell biology 14 (9), 549-562, 2013
3392013
A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes
D Clift, M Schuh
Nature communications 6 (1), 7217, 2015
1662015
Anti-commensal IgG drives intestinal inflammation and type 17 immunity in ulcerative colitis
T Castro-Dopico, TW Dennison, JR Ferdinand, RJ Mathews, A Fleming, ...
Immunity 50 (4), 1099-1114. e10, 2019
1652019
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation
WA McEwan, B Falcon, M Vaysburd, D Clift, AL Oblak, B Ghetti, ...
Proceedings of the National Academy of Sciences 114 (3), 574-579, 2017
1522017
A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes
C So, KB Seres, AM Steyer, E Mönnich, D Clift, A Pejkovska, W Möbius, ...
Science 364 (6447), eaat9557, 2019
1372019
Acute and rapid degradation of endogenous proteins by Trim-Away
D Clift, C So, WA McEwan, LC James, M Schuh
Nature Protocols 13 (10), 2149-2175, 2018
1272018
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome
G Balmus, D Larrieu, AC Barros, C Collins, M Abrudan, M Demir, ...
Nature communications 9 (1), 1700, 2018
1192018
Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere
KF Verzijlbergen, OO Nerusheva, D Kelly, A Kerr, D Clift, F de Lima Alves, ...
Elife 3, e01374, 2014
952014
Shugoshin prevents cohesin cleavage by PP2ACdc55-dependent inhibition of separase
D Clift, F Bizzari, AL Marston
Genes & development 23 (6), 766-780, 2009
772009
The role of shugoshin in meiotic chromosome segregation
D Clift, AL Marston
Cytogenetic and genome research 133 (2-4), 234-242, 2011
732011
Complement C4 prevents viral infection through capsid inactivation
M Bottermann, S Foss, SL Caddy, D Clift, LM van Tienen, M Vaysburd, ...
Cell host & microbe 25 (4), 617-629. e7, 2019
572019
Target-induced clustering activates Trim-Away of pathogens and proteins
J Zeng, AF Santos, AS Mukadam, M Osswald, DA Jacques, CF Dickson, ...
Nature structural & molecular biology 28 (3), 278-289, 2021
492021
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
LI Labzin, M Bottermann, P Rodriguez‐Silvestre, S Foss, JT Andersen, ...
The EMBO Journal 38 (21), e101365, 2019
352019
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination
L Kiss, D Clift, N Renner, D Neuhaus, LC James
Nature Communications 12 (1), 1220, 2021
342021
A functional assay for serum detection of antibodies against SARS‐CoV‐2 nucleoprotein
A Albecka, D Clift, M Vaysburd, T Rhinesmith, SL Caddy, DM Favara, ...
The EMBO journal 40 (17), e108588, 2021
172021
SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase
XB Su, M Wang, C Schaffner, OO Nerusheva, D Clift, C Spanos, DA Kelly, ...
Journal of Cell Biology 220 (7), e202005130, 2021
102021
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates
L Kiss, T Rhinesmith, J Luptak, CF Dickson, J Weidenhausen, S Smyly, ...
Nature Communications 14 (1), 2160, 2023
42023
TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease processing
J Luptak, DL Mallery, AS Jahun, A Albecka, D Clift, O Ather, G Slodkowicz, ...
Viruses 14 (8), 1610, 2022
32022
Trim-Away degrades lysine-less substrates without requiring ligase autoubiquitination
L Kiss, T Rhinesmith, CF Dickson, J Weidenhausen, S Smyly, J Luptak, ...
bioRxiv, 2022.06. 29.498105, 2022
22022
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Artikler 1–20