Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ... Nature immunology 11 (1), 63-69, 2010 | 577 | 2010 |
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 M Rebsamen, L Pochini, T Stasyk, MEG de Araújo, M Galluccio, ... Nature 519 (7544), 477-481, 2015 | 571 | 2015 |
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ... ACS chemical biology 10 (7), 1604-1609, 2015 | 395 | 2015 |
TRADD protein is an essential component of the RIG-like helicase antiviral pathway MC Michallet, E Meylan, MA Ermolaeva, J Vazquez, M Rebsamen, ... Immunity 28 (5), 651-661, 2008 | 355 | 2008 |
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ... EMBO reports 10 (8), 916-922, 2009 | 304 | 2009 |
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells F Staehli, K Ludigs, LX Heinz, Q Seguín-Estévez, I Ferrero, M Braun, ... The Journal of Immunology 188 (8), 3820-3828, 2012 | 141 | 2012 |
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis GSF A Fauster, M Rebsamen, K V M Huber, J W Bigenzahn, A Stukalov, C-H ... Cell Death and Disease, 2015 | 137 | 2015 |
A reversible gene trap collection empowers haploid genetics in human cells T Bürckstümmer, C Banning, P Hainzl, R Schobesberger, C Kerzendorfer, ... Nature methods 10 (10), 965-971, 2013 | 100 | 2013 |
LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 95 | 2018 |
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases M Rebsamen, E Meylan, J Curran, J Tschopp Cell Death & Differentiation 15 (11), 1804-1811, 2008 | 82 | 2008 |
NLRX1/NOD5 deficiency does not affect MAVS signalling M Rebsamen, J Vazquez, A Tardivel, G Guarda, J Curran, J Tschopp Cell Death & Differentiation 18 (8), 1387-1387, 2011 | 79 | 2011 |
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning HLA Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen ... J Cell Biol, 2017 | 75 | 2017 |
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ... Cell reports 11 (12), 1919-1928, 2015 | 73 | 2015 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 61 | 2020 |
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 45 | 2018 |
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1 M Rebsamen, G Superti-Furga Autophagy 12 (6), 1061-1062, 2016 | 32 | 2016 |
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import E Girardi, G Agrimi, U Goldmann, G Fiume, S Lindinger, V Sedlyarov, ... Nature communications 11 (1), 1-9, 2020 | 31 | 2020 |
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an … JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ... Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016 | 27 | 2016 |
A time-resolved molecular map of the macrophage response to VSV infection Kandasamy RK, Vladimir GI, Snijder B, Müller AC, Rebsamen M, Bigenzahn JW ... npj Systems Biology and Applications, 2016 | 27 | 2016 |
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade LX Heinz, M Rebsamen, DC Rossi, F Staehli, K Schroder, M Quadroni, ... Cell Death & Differentiation 19 (4), 722-731, 2012 | 27 | 2012 |