Manuele Rebsamen
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Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ...
Nature immunology 11 (1), 63-69, 2010
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
M Rebsamen, L Pochini, T Stasyk, MEG de Araújo, M Galluccio, ...
Nature 519 (7544), 477-481, 2015
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ...
ACS chemical biology 10 (7), 1604-1609, 2015
TRADD protein is an essential component of the RIG-like helicase antiviral pathway
MC Michallet, E Meylan, MA Ermolaeva, J Vazquez, M Rebsamen, ...
Immunity 28 (5), 651-661, 2008
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB
M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ...
EMBO reports 10 (8), 916-922, 2009
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells
F Staehli, K Ludigs, LX Heinz, Q Seguín-Estévez, I Ferrero, M Braun, ...
The Journal of Immunology 188 (8), 3820-3828, 2012
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
GSF A Fauster, M Rebsamen, K V M Huber, J W Bigenzahn, A Stukalov, C-H ...
Cell Death and Disease, 2015
A reversible gene trap collection empowers haploid genetics in human cells
T Bürckstümmer, C Banning, P Hainzl, R Schobesberger, C Kerzendorfer, ...
Nature methods 10 (10), 965-971, 2013
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases
M Rebsamen, E Meylan, J Curran, J Tschopp
Cell Death & Differentiation 15 (11), 1804-1811, 2008
NLRX1/NOD5 deficiency does not affect MAVS signalling
M Rebsamen, J Vazquez, A Tardivel, G Guarda, J Curran, J Tschopp
Cell Death & Differentiation 18 (8), 1387-1387, 2011
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
HLA Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen ...
J Cell Biol, 2017
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity
LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ...
Cell reports 11 (12), 1919-1928, 2015
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ...
Nature 581 (7808), 316-322, 2020
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification
V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ...
Cell host & microbe 23 (6), 766-774. e5, 2018
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1
M Rebsamen, G Superti-Furga
Autophagy 12 (6), 1061-1062, 2016
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import
E Girardi, G Agrimi, U Goldmann, G Fiume, S Lindinger, V Sedlyarov, ...
Nature communications 11 (1), 1-9, 2020
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an …
JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ...
Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016
A time-resolved molecular map of the macrophage response to VSV infection
Kandasamy RK, Vladimir GI, Snijder B, Müller AC, Rebsamen M, Bigenzahn JW ...
npj Systems Biology and Applications, 2016
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade
LX Heinz, M Rebsamen, DC Rossi, F Staehli, K Schroder, M Quadroni, ...
Cell Death & Differentiation 19 (4), 722-731, 2012
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