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Charles H. Li
Charles H. Li
Choate, Hall & Stewart LLP
Verifisert e-postadresse på choate.com
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Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
13582018
Transcription factors activate genes through the phase-separation capacity of their activation domains
A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ...
Cell 175 (7), 1842-1855. e16, 2018
9052018
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science 351 (6280), 1454-1458, 2016
8582016
Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
WK Cho, JH Spille, M Hecht, C Lee, C Li, V Grube, II Cisse
Science 361 (6400), 412-415, 2018
8112018
YY1 is a structural regulator of enhancer-promoter loops
AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ...
Cell 171 (7), 1573-1588. e28, 2017
6432017
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
3242018
Partitioning of cancer therapeutics in nuclear condensates
IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ...
Science 368 (6497), 1386-1392, 2020
1662020
Mediator condensates localize signaling factors to key cell identity genes
AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ...
Molecular Cell 76 (5), 753-766. e6, 2019
1272019
Engineering of a histone-recognition domain in Dnmt3a alters the epigenetic landscape and phenotypic features of mouse ESCs
KM Noh, H Wang, HR Kim, W Wenderski, F Fang, CH Li, S Dewell, ...
Molecular cell 59 (1), 89-103, 2015
782015
MeCP2 links heterochromatin condensates and neurodevelopmental disease
CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ...
Nature, 1-8, 2020
772020
Small genomic insertions form enhancers that misregulate oncogenes
BJ Abraham, D Hnisz, AS Weintraub, N Kwiatkowski, CH Li, Z Li, ...
Nature communications 8, 14385, 2017
692017
Chromatin kinases act on transcription factors and histone tails in regulation of inducible transcription
SZ Josefowicz, M Shimada, A Armache, CH Li, RM Miller, S Lin, A Yang, ...
Molecular cell 64 (2), 347-361, 2016
542016
Regulation and dysregulation of chromosome structure in cancer
D Hnisz, J Schuijers, CH Li, RA Young
Annual Review of Cancer Biology 2, 21-40, 2018
292018
Differential cofactor dependencies define distinct types of human enhancers
C Neumayr, V Haberle, L Serebreni, K Karner, O Hendy, A Boija, ...
Nature, 1-8, 2022
72022
Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription
S Pomplun, M Jbara, CK Schissel, S Wilson Hawken, A Boija, C Li, I Klein, ...
ACS Central Science, 2021
42021
Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops
RA Young, AS Weintraub, CH Li, AA Sigova
US Patent App. 16/476,868, 2019
22019
Three-dimensional gene regulatory landscapes in normal and cancer cells
BJ Abraham, YE Guo, D Hnisz, CH Li, AS Weintraub, DS Day, J Schuijers, ...
Cancer Research 78 (13 Supplement), 971-971, 2018
2018
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Artikler 1–17